CircuLex Mouse/Rat PCSK9 ELISA Kit

MBL Life Sciences

Catalog No: MBL-CY-8078

The CycLex Research Product CircuLex Mouse/Rat PCSK9 ELISA Kit is used for the quantitative measurement of Mouse and Rat PCSK9 in serum, plasma, cell culture medium and other biological media. It can be used for 96 Assays.

Product Specifications

• Application: ELISA
• Sensitivity: better than 38.1 pg/ml of sample.

Citations for CircuLex Mouse/Rat PCSK9 ELISA Kit – 22 Found

Chen, Xiao-Wei; Wang, He; Bajaj, Kanika; Zhang, Pengcheng; Meng, Zhuo-Xian; Ma, Danjun; Bai, Yongsheng; Liu, Hui-Hui; Adams, Elizabeth; Baines, Andrea; Yu, Genggeng; Sartor, Maureen A; Zhang, Bin; Yi, Zhengping; Lin, Jiandie; Young, Stephen G; Schekman, Randy; Ginsburg, David. SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. Elife. 2013;2:e00444. 

Carrier, Bradley; Wen, Shin; Zigouras, Sophia; Browne, Richard W; Li, Zhuyun; Patel, Mulchand S; Williamson, David L; Rideout, Todd C. Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats. Plos One. 9(3):e90863. 

Sasaki, Makoto; Terao, Yoshio; Ayaori, Makoto; Uto-Kondo, Harumi; Iizuka, Maki; Yogo, Makiko; Hagisawa, Kosuke; Takiguchi, Shunichi; Yakushiji, Emi; Nakaya, Kazuhiro; Ogura, Masatsune; Komatsu, Tomohiro; Ikewaki, Katsunori. Hepatic overexpression of idol increases circulating protein convertase subtilisin/kexin type 9 in mice and hamsters via dual mechanisms: sterol regulatory element-binding protein 2 and low-density lipoprotein receptor-dependent pathways. Arteriosclerosis, Thrombosis, And Vascular Biology. 2014;34(6):1171-8. 

Galabova, Gergana; Brunner, Sylvia; Winsauer, Gabriele; Juno, Claudia; Wanko, Bettina; Mairhofer, Andreas; Lührs, Petra; Schneeberger, Achim; von Bonin, Arne; Mattner, Frank; Schmidt, Walter; Staffler, Guenther. Peptide-based anti-PCSK9 vaccines - an approach for long-term LDLc management. Plos One. 9(12):e114469. 

Berger, Jean-Mathieu; Vaillant, Nathalie; Le May, Cédric; Calderon, Carolina; Brégeon, Jeremy; Prieur, Xavier; Hadchouel, Juliette; Loirand, Gervaise; Cariou, Bertrand. PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension. Atherosclerosis. 2015;239(1):252-9. 

Butkinaree, Chutikarn; Canuel, Maryssa; Essalmani, Rachid; Poirier, Steve; Benjannet, Suzanne; Asselin, Marie-Claude; Roubtsova, Anna; Hamelin, Josée; Marcinkiewicz, Jadwiga; Chamberland, Ann; Guillemot, Johann; Mayer, Gaétan; Sisodia, Sangram S; Jacob, Yves; Prat, Annik; Seidah, Nabil G. Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other. The Journal Of Biological Chemistry. 2015;290(30):18609-20. 

An, Dong; Wei, Xiaowei; Li, Hui; Gu, Hui; Huang, Tianchu; Zhao, Guifeng; Liu, Bo; Wang, Weilin; Chen, Lizhu; Ma, Wei; Zhang, Henan; Cao, Songying; Yuan, Zhengwei. Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics. Scientific Reports. 2015;5:17559. 

Haas, Mary E; Levenson, Amy E; Sun, Xiaowei; Liao, Wan-Hui; Rutkowski, Joseph M; de Ferranti, Sarah D; Schumacher, Valerie A; Scherer, Philipp E; Salant, David J; Biddinger, Sudha B. The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia. Circulation. 2016;134(1):61-72. 

Ngo Sock, Emilienne Tudor; Mayer, Gaétan; Lavoie, Jean-Marc. Combined Effects of Rosuvastatin and Exercise on Gene Expression of Key Molecules Involved in Cholesterol Metabolism in Ovariectomized Rats. Plos One. 11(7):e0159550. 

Lintner, Nathanael G; McClure, Kim F; Petersen, Donna; Londregan, Allyn T; Piotrowski, David W; Wei, Liuqing; Xiao, Jun; Bolt, Michael; Loria, Paula M; Maguire, Bruce; Geoghegan, Kieran F; Huang, Austin; Rolph, Tim; Liras, Spiros; Doudna, Jennifer A; Dullea, Robert G; Cate, Jamie H D. Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain. Plos Biology. 2017;15(3):e2001882. 

Xu, Yu-Xin; Redon, Valeska; Yu, Haojie; Querbes, William; Pirruccello, James; Liebow, Abigail; Deik, Amy; Trindade, Kevin; Wang, Xiao; Musunuru, Kiran; Clish, Clary B; Cowan, Chad; Fizgerald, Kevin; Rader, Daniel; Kathiresan, Sekar. Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. Atherosclerosis. 2018;268:196-206. 

Yang, Sheng-Hua; Xu, Rui-Xia; Cui, Chuan-Jue; Wang, Yin; Du, Ying; Chen, Zhi-Guo; Yao, Yu-Hong; Ma, Chun-Yan; Zhu, Cheng-Gang; Guo, Yuan-Lin; Wu, Na-Qiong; Sun, Jing; Chen, Bu-Xing; Li, Jian-Jun. Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism. Cardiovascular Diabetology. 2018;17(1):48. 

Ding, Zufeng; Wang, Xianwei; Liu, Shijie; Shahanawaz, Jiwani; Theus, Sue; Fan, Yubo; Deng, Xiaoyan; Zhou, Sichang; Mehta, Jawahar L. PCSK9 expression in the ischaemic heart and its relationship to infarct size, cardiac function, and development of autophagy. Cardiovascular Research. 2018;114(13):1738-1751. 

Liu, Yan; Wang, Xiaona; Han, Jie; Liu, Lu; Jin, Ying; Jin, Liyuan; Ye, Ping. PCSK9 positively correlates with plasma sdLDL in community-dwelling population but not in diabetic participants after confounder adjustment. Medicine. 2019;98(14):e15062. 

Momtazi-Borojeni, Amir Abbas; Nik, Maryam Ebrahimi; Jaafari, Mahmoud Reza; Banach, Maciej; Sahebkar, Amirhossein. Potential anti-tumor effect of a nanoliposomal antiPCSK9 vaccine in mice bearing colorectal cancer. Archives Of Medical Science : Ams. 2019;15(3):559-569. 

Momtazi-Borojeni, Amir Abbas; Nik, Maryam Ebrahimi; Jaafari, Mahmoud Reza; Banach, Maciej; Sahebkar, Amirhossein. Effects of immunization against PCSK9 in an experimental model of breast cancer. Archives Of Medical Science : Ams. 2019;15(3):570-579. 

Momtazi-Borojeni, Amir Abbas; Jaafari, Mahmoud Reza; Badiee, Ali; Banach, Maciej; Sahebkar, Amirhossein. Therapeutic effect of nanoliposomal PCSK9 vaccine in a mouse model of atherosclerosis. Bmc Medicine. 2019;17(1):223. 

Momtazi-Borojeni, Amir Abbas; Nik, Maryam Ebrahimi; Jaafari, Mahmoud Reza; Banach, Maciej; Sahebkar, Amirhossein. Effects of immunisation against PCSK9 in mice bearing melanoma. Archives Of Medical Science : Ams. 16(1):189-199. 

Low, Lauretta D; Lu, Liangjian; Chan, Chang-Yien; Chen, Jinmiao; Yang, Henry H; Yu, Hanry; Lee, Caroline G L; Ng, Kar-Hui; Yap, Hui-Kim. IL-13-driven alterations in hepatic cholesterol handling contributes to hypercholesterolemia in a rat model of minimal change disease. Clinical Science (London, England : 1979). 2020;134(2):225-237. 

Evison, Benny J; Palmer, James T; Lambert, Gilles; Treutlein, Herbert; Zeng, Jun; Nativel, Brice; Chemello, Kévin; Zhu, Qing; Wang, Jie; Teng, Yanfen; Tang, Wei; Xu, Yanfeng; Rathi, Anuj Kumar; Kumar, Sanjay; Suchowerska, Alexandra K; Parmar, Jasneet; Dixon, Ian; Kelly, Graham E; Bonnar, James. A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove. Bioorganic & Medicinal Chemistry. 2020;28(6):115344. 

St-Amand, Roxane; Ngo Sock, Émilienne T; Quinn, Samantha; Lavoie, Jean-Marc; St-Pierre, David H. Two weeks of western diet disrupts liver molecular markers of cholesterol metabolism in rats. Lipids In Health And Disease. 2020;19(1):192. 

Ding, Zufeng; Wang, Xianwei; Liu, Shijie; Zhou, Sichang; Kore, Rajshekhar A; Mu, Shengyu; Deng, Xiaoyan; Fan, Yubo; Mehta, Jawahar L. NLRP3 inflammasome via IL-1β regulates PCSK9 secretion. Theranostics. 10(16):7100-7110.