This kit is primarily designed for the semi-quantitative in vitro measurement of functionally active of PCSK9 in serum and plasma, which is capable of binding to LDL receptor (LDLR). This kit allows to measure active PCSK9 in a solid-phase assay system based on a conventional ELISA in a semi-quantitative manner.
| Product Specifications | |
| Application | ELISA |
| Sensitivity | 0.042 mAU/mL - |
| Citations for CircuLex Human PCSK9 Functional Assay Kit – 1 Found |
| Ben Djoudi Ouadda, Ali; Gauthier, Marie-Soleil; Susan-Resiga, Delia; Girard, Emmanuelle; Essalmani, Rachid; Black, Miles; Marcinkiewicz, Jadwiga; Forget, Diane; Hamelin, Josée; Evagelidis, Alexandra; Ly, Kevin; Day, Robert; Galarneau, Luc; Corbin, Francois; Coulombe, Benoit; Çaku, Artuela; Tagliabracci, Vincent S; Seidah, Nabil G. Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor). Arteriosclerosis, Thrombosis, And Vascular Biology. 2019;39(10):1996-2013. PubMed - Comments: Used in: Function |