| Citations for CircuLex Human PCSK9 ELISA Kit – 47 Found |
| Noguchi, Tohru; Katsuda, Shoji; Kawashiri, Masa-Aki; Tada, Hayato; Nohara, Atsushi; Inazu, Akihiro; Yamagishi, Masakazu; Kobayashi, Junji; Mabuchi, Hiroshi. The E32K variant of PCSK9 exacerbates the phenotype of familial hypercholesterolaemia by increasing PCSK9 function and concentration in the circulation. Atherosclerosis. 2010;210(1):166-72. PubMed |
| Cariou, Bertrand; Le Bras, Maëlle; Langhi, Cédric; Le May, Cédric; Guyomarc'h-Delasalle, Béatrice; Krempf, Michel; Costet, Philippe. Association between plasma PCSK9 and gamma-glutamyl transferase levels in diabetic patients. Atherosclerosis. 2010;211(2):700-2. PubMed |
| Costet, P; Hoffmann, M M; Cariou, B; Guyomarc'h Delasalle, B; Konrad, T; Winkler, K. Plasma PCSK9 is increased by fenofibrate and atorvastatin in a non-additive fashion in diabetic patients. Atherosclerosis. 2010;212(1):246-51. PubMed |
| Noguchi, Tohru; Kobayashi, Junji; Yagi, Kunimasa; Nohara, Atsushi; Yamaaki, Naoto; Sugihara, Masako; Ito, Naoko; Oka, Rie; Kawashiri, Masa-Aki; Tada, Hayato; Takata, Mutsuko; Inazu, Akihiro; Yamagishi, Masakazu; Mabuchi, Hiroshi. Comparison of effects of bezafibrate and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 and adipocytokine levels in dyslipidemic subjects with impaired glucose tolerance or type 2 diabetes mellitus: results from a crossover study. Atherosclerosis. 2011;217(1):165-70. PubMed |
| Mayne, Janice; Dewpura, Thilina; Raymond, Angela; Bernier, Lise; Cousins, Marion; Ooi, Teik Chye; Davignon, Jean; Seidah, Nabil G; Mbikay, Majambu; Chrétien, Michel. Novel loss-of-function PCSK9 variant is associated with low plasma LDL cholesterol in a French-Canadian family and with impaired processing and secretion in cell culture. Clinical Chemistry. 2011;57(10):1415-23. PubMed |
| Vergès, Bruno; Duvillard, Laurence; Brindisi, Marie Claude; Gautier, Emmanuel; Krempf, Michel; Costet, Philippe; Cariou, Bertrand. Lack of association between plasma PCSK9 and LDL-apoB100 catabolism in patients with uncontrolled type 2 diabetes. Atherosclerosis. 2011;219(1):342-8. PubMed |
| Cariou, Bertrand; Le May, Cédric; Costet, Philippe. Clinical aspects of PCSK9. Atherosclerosis. 2011;216(2):258-65. PubMed |
| Persson, Lena; Henriksson, Peter; Westerlund, Eli; Hovatta, Outi; Angelin, Bo; Rudling, Mats. Endogenous estrogens lower plasma PCSK9 and LDL cholesterol but not Lp(a) or bile acid synthesis in women. Arteriosclerosis, Thrombosis, And Vascular Biology. 2012;32(3):810-4. PubMed |
| Kawashiri, Masa-Aki; Nohara, Atsushi; Noguchi, Tohru; Tada, Hayato; Nakanishi, Chiaki; Mori, Mika; Konno, Tetsuo; Hayashi, Kenshi; Fujino, Noboru; Inazu, Akihiro; Kobayashi, Junji; Mabuchi, Hiroshi; Yamagishi, Masakazu. Efficacy and safety of coadministration of rosuvastatin, ezetimibe, and colestimide in heterozygous familial hypercholesterolemia. The American Journal Of Cardiology. 2012;109(3):364-9. PubMed |
| Lindholm, Marie W; Elmén, Joacim; Fisker, Niels; Hansen, Henrik F; Persson, Robert; Møller, Marianne R; Rosenbohm, Christoph; Ørum, Henrik; Straarup, Ellen M; Koch, Troels. PCSK9 LNA antisense oligonucleotides induce sustained reduction of LDL cholesterol in nonhuman primates. Molecular Therapy : The Journal Of The American Society Of Gene Therapy. 2012;20(2):376-81. PubMed |
| Cameron, Jamie; Bogsrud, Martin P; Tveten, Kristian; Strøm, Thea Bismo; Holven, Kirsten; Berge, Knut Erik; Leren, Trond P. Serum levels of proprotein convertase subtilisin/kexin type 9 in subjects with familial hypercholesterolemia indicate that proprotein convertase subtilisin/kexin type 9 is cleared from plasma by low-density lipoprotein receptor-independent pathways. Translational Research : The Journal Of Laboratory And Clinical Medicine. 2012;160(2):125-30. PubMed |
| Huijgen, R; Fouchier, S W; Denoun, M; Hutten, B A; Vissers, M N; Lambert, G; Kastelein, J J P. Plasma levels of PCSK9 and phenotypic variability in familial hypercholesterolemia. Journal Of Lipid Research. 2012;53(5):979-983. PubMed |
| Cariou, Bertrand; Langhi, Cédric; Le Bras, Maëlle; Bortolotti, Murielle; Lê, Kim-Anne; Theytaz, Fanny; Le May, Cédric; Guyomarc'h-Delasalle, Béatrice; Zaïr, Yassine; Kreis, Roland; Boesch, Chris; Krempf, Michel; Tappy, Luc; Costet, Philippe. Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets. Nutrition & Metabolism. 2013;10(1):4. PubMed |
| Lee, Chan Joo; Lee, Yong-Ho; Park, Sahng Wook; Kim, Kwang Joon; Park, Sungha; Youn, Jong-Chan; Lee, Sang-Hak; Kang, Seok-Min; Jang, Yangsoo. Association of serum proprotein convertase subtilisin/kexin type 9 with carotid intima media thickness in hypertensive subjects. Metabolism: Clinical And Experimental. 2013;62(6):845-50. PubMed |
| Le Bras, Maëlle; Roquilly, Antoine; Deckert, Valérie; Langhi, Cédric; Feuillet, Fanny; Sébille, Véronique; Mahé, Pierre-Joachim; Bach, Kalyane; Masson, Damien; Lagrost, Laurent; Costet, Philippe; Asehnoune, Karim; Cariou, Bertrand. Plasma PCSK9 is a late biomarker of severity in patients with severe trauma injury. The Journal Of Clinical Endocrinology And Metabolism. 2013;98(4):E732-6. PubMed |
| Mayne, Janice; Ooi, Teik Chye; Raymond, Angela; Cousins, Marion; Bernier, Lise; Dewpura, Thilina; Sirois, Francine; Mbikay, Majambu; Davignon, Jean; Chrétien, Michel. Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations. Lipids In Health And Disease. 2013;12:70. PubMed |
| Peticca, Patricia; Raymond, Angela; Gruslin, Andrée; Cousins, Marion; Adetola, Ejibunmi; Abujrad, Hussein; Mayne, Janice; Ooi, Teik Chye. Human Serum PCSK9 Is Elevated at Parturition in Comparison to Nonpregnant Subjects While Serum PCSK9 from Umbilical Cord Blood is Lower Compared to Maternal Blood. Isrn Endocrinology. 2013:341632. PubMed |
| Tremblay, André J; Lamarche, Benoît; Guay, Valérie; Charest, Amélie; Lemelin, Valéry; Couture, Patrick. Short-term, high-fat diet increases the expression of key intestinal genes involved in lipoprotein metabolism in healthy men. The American Journal Of Clinical Nutrition. 2013;98(1):32-41. PubMed |
| Conway, V; Couture, P; Richard, C; Gauthier, S F; Pouliot, Y; Lamarche, B. Impact of buttermilk consumption on plasma lipids and surrogate markers of cholesterol homeostasis in men and women. Nutrition, Metabolism, And Cardiovascular Diseases : Nmcd. 2013;23(12):1255-62. PubMed |
| Lambert, Gilles; Petrides, Francine; Chatelais, Mathias; Blom, Dirk J; Choque, Benjamin; Tabet, Fatiha; Wong, Gida; Rye, Kerry-Anne; Hooper, Amanda J; Burnett, John R; Barter, Philip J; Marais, A David. Elevated plasma PCSK9 level is equally detrimental for patients with nonfamilial hypercholesterolemia and heterozygous familial hypercholesterolemia, irrespective of low-density lipoprotein receptor defects. Journal Of The American College Of Cardiology. 2014;63(22):2365-73. PubMed |
| Werner, Christian; Hoffmann, Michael M; Winkler, Karl; Böhm, Michael; Laufs, Ulrich. Risk prediction with proprotein convertase subtilisin/kexin type 9 (PCSK9) in patients with stable coronary disease on statin treatment. Vascular Pharmacology. 2014;62(2):94-102. PubMed |
| Abujrad, H; Mayne, J; Ruzicka, M; Cousins, M; Raymond, A; Cheesman, J; Taljaard, M; Sorisky, A; Burns, K; Ooi, T C. Chronic kidney disease on hemodialysis is associated with decreased serum PCSK9 levels. Atherosclerosis. 2014;233(1):123-9. PubMed |
| Jia, Yan-jun; Zhang, Yan; Liu, Jun; Guo, Yuan-lin; Xu, Rui-xia; Li, Jian-jun. Short- and long-term effects of xuezhikang, an extract of cholestin, on serum proprotein convertase subtilisin/kexin type 9 levels. Chinese Journal Of Integrative Medicine. 2016;22(2):96-100. PubMed |
| Bonde, Ylva; Breuer, Olof; Lütjohann, Dieter; Sjöberg, Stefan; Angelin, Bo; Rudling, Mats. Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans. Journal Of Lipid Research. 2014;55(11):2408-15. PubMed |
| Mbikay, Majambu; Sirois, Francine; Simoes, Sonia; Mayne, Janice; Chrétien, Michel. Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture. Febs Open Bio. 4:755-62. PubMed |
| Iggman, David; Rosqvist, Fredrik; Larsson, Anders; Arnlöv, Johan; Beckman, Lena; Rudling, Mats; Risérus, Ulf. Role of dietary fats in modulating cardiometabolic risk during moderate weight gain: a randomized double-blind overfeeding trial (LIPOGAIN study). Journal Of The American Heart Association. 2014;3(5):e001095. PubMed |
| Xu, Rui-Xia; Li, Sha; Zhang, Yan; Li, Xiao-Lin; Guo, Yuan-Lin; Zhu, Cheng-Gang; Li, Jian-Jun. Relation of plasma PCSK9 levels to lipoprotein subfractions in patients with stable coronary artery disease. Lipids In Health And Disease. 2014;13:188. PubMed |
| Ghosh, Moumita; Gälman, Cecilia; Rudling, Mats; Angelin, Bo. Influence of physiological changes in endogenous estrogen on circulating PCSK9 and LDL cholesterol. Journal Of Lipid Research. 2015;56(2):463-9. PubMed |
| Xu, Rui-Xia; Liu, Jun; Li, Xiao-Lin; Li, Sha; Zhang, Yan; Jia, Yan-Jun; Sun, Jing; Li, Jian-Jun. Impacts of ezetimibe on PCSK9 in rats: study on the expression in different organs and the potential mechanisms. Journal Of Translational Medicine. 2015;13:87. PubMed |
| Starr, Amanda E; Lemieux, Valérie; Noad, Jenny; Moore, Jasmine I; Dewpura, Thilina; Raymond, Angela; Chrétien, Michel; Figeys, Daniel; Mayne, Janice. β-Estradiol results in a proprotein convertase subtilisin/kexin type 9-dependent increase in low-density lipoprotein receptor levels in human hepatic HuH7 cells. The Febs Journal. 2015;282(14):2682-96. PubMed |
| Rosqvist, Fredrik; Smedman, Annika; Lindmark-Månsson, Helena; Paulsson, Marie; Petrus, Paul; Straniero, Sara; Rudling, Mats; Dahlman, Ingrid; Risérus, Ulf. Potential role of milk fat globule membrane in modulating plasma lipoproteins, gene expression, and cholesterol metabolism in humans: a randomized study. The American Journal Of Clinical Nutrition. 2015;102(1):20-30. PubMed |
| Butkinaree, Chutikarn; Canuel, Maryssa; Essalmani, Rachid; Poirier, Steve; Benjannet, Suzanne; Asselin, Marie-Claude; Roubtsova, Anna; Hamelin, Josée; Marcinkiewicz, Jadwiga; Chamberland, Ann; Guillemot, Johann; Mayer, Gaétan; Sisodia, Sangram S; Jacob, Yves; Prat, Annik; Seidah, Nabil G. Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other. The Journal Of Biological Chemistry. 2015;290(30):18609-20. PubMed |
| van Poelgeest, Eveline P; Hodges, Michael R; Moerland, Matthijs; Tessier, Yann; Levin, Arthur A; Persson, Robert; Lindholm, Marie W; Dumong Erichsen, Kamille; Ørum, Henrik; Cohen, Adam F; Burggraaf, Jacobus. Antisense-mediated reduction of proprotein convertase subtilisin/kexin type 9 (PCSK9): a first-in-human randomized, placebo-controlled trial. British Journal Of Clinical Pharmacology. 2015;80(6):1350-61. PubMed |
| Wassef, Hanny; Bissonnette, Simon; Saint-Pierre, Nathalie; Lamantia, Valérie; Cyr, Yannick; Chrétien, Michel; Faraj, May. The apoB-to-PCSK9 ratio: A new index for metabolic risk in humans. Journal Of Clinical Lipidology. 2015;9(5):664-75. PubMed |
| Si-Tayeb, Karim; Idriss, Salam; Champon, Benoite; Caillaud, Amandine; Pichelin, Matthieu; Arnaud, Lucie; Lemarchand, Patricia; Le May, Cédric; Zibara, Kazem; Cariou, Bertrand. Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia. Disease Models & Mechanisms. 2016;9(1):81-90. PubMed |
| Rogacev, Kyrill S; Heine, Gunnar H; Silbernagel, Günther; Kleber, Marcus E; Seiler, Sarah; Emrich, Insa; Lennartz, Simone; Werner, Christian; Zawada, Adam M; Fliser, Danilo; Böhm, Michael; März, Winfried; Scharnagl, Hubert; Laufs, Ulrich. PCSK9 Plasma Concentrations Are Independent of GFR and Do Not Predict Cardiovascular Events in Patients with Decreased GFR. Plos One. 11(1):e0146920. PubMed |
| Milasan, Andreea; Dallaire, François; Mayer, Gaétan; Martel, Catherine. Effects of LDL Receptor Modulation on Lymphatic Function. Scientific Reports. 2016;6:27862. PubMed |
| Vlachopoulos, Charalambos; Terentes-Printzios, Dimitrios; Georgiopoulos, Georgios; Skoumas, Ioannis; Koutagiar, Iosif; Ioakeimidis, Nikolaos; Stefanadis, Christodoulos; Tousoulis, Dimitrios. Prediction of cardiovascular events with levels of proprotein convertase subtilisin/kexin type 9: A systematic review and meta-analysis. Atherosclerosis. 2016;252:50-60. PubMed |
| Li, Sha; Zhao, Xi; Zhang, Yan; Zhu, Cheng-Gang; Guo, Yuan-Lin; Wu, Na-Qiong; Xu, Rui-Xia; Qing, Ping; Gao, Ying; Sun, Jing; Liu, Geng; Dong, Qian; Li, Jian-Jun. Novel circulating lipid measurements for current dyslipidemias in non-treated patients undergoing coronary angiography: PCSK9, apoC3 and sdLDL-C. Oncotarget. 2017;8(7):12333-12341. PubMed |
| Navarese, Eliano P; Kolodziejczak, Michalina; Winter, Max-Paul; Alimohammadi, Arman; Lang, Irene M; Buffon, Antonino; Lip, Gregory Yh; Siller-Matula, Jolanta M. Association of PCSK9 with platelet reactivity in patients with acute coronary syndrome treated with prasugrel or ticagrelor: The PCSK9-REACT study. International Journal Of Cardiology. 2017;227:644-649. PubMed |
| Suzuki, Yuta; Hyodo, Kenji; Suzuki, Takuya; Tanaka, Yohei; Kikuchi, Hiroshi; Ishihara, Hiroshi. Biodegradable lipid nanoparticles induce a prolonged RNA interference-mediated protein knockdown and show rapid hepatic clearance in mice and nonhuman primates. International Journal Of Pharmaceutics. 2017;519(1-2):34-43. PubMed |
| Li, Sha; Guo, Yuan-Lin; Zhao, Xi; Zhang, Yan; Zhu, Cheng-Gang; Wu, Na-Qiong; Xu, Rui-Xia; Qing, Ping; Gao, Ying; Li, Xiao-Lin; Sun, Jing; Liu, Geng; Dong, Qian; Li, Jian-Jun. Novel and traditional lipid-related biomarkers and their combinations in predicting coronary severity. Scientific Reports. 2017;7(1):360. PubMed |
| Hyrina, Anastasia; Olmstead, Andrea D; Steven, Paul; Krajden, Mel; Tam, Edward; Jean, François. Treatment-Induced Viral Cure of Hepatitis C Virus-Infected Patients Involves a Dynamic Interplay among three Important Molecular Players in Lipid Homeostasis: Circulating microRNA (miR)-24, miR-223, and Proprotein Convertase Subtilisin/Kexin Type 9. Ebiomedicine. 2017;23:68-78. PubMed |
| Blanchard, C; Moreau, F; Ayer, A; Toque, L; Garçon, D; Arnaud, L; Borel, F; Aguesse, A; Croyal, M; Krempf, M; Prieur, X; Neunlist, M; Cariou, B; Le May, C. Roux-en-Y gastric bypass reduces plasma cholesterol in diet-induced obese mice by affecting trans-intestinal cholesterol excretion and intestinal cholesterol absorption. International Journal Of Obesity (2005). 2018;42(3):552-560. PubMed |
| Iacocca, Michael A; Wang, Jian; Sarkar, Samantha; Dron, Jacqueline S; Lagace, Thomas; McIntyre, Adam D; Lau, Paulina; Robinson, John F; Yang, Ping; Knoll, Joan H; Cao, Henian; McPherson, Ruth; Hegele, Robert A. Whole-Gene Duplication of PCSK9 as a Novel Genetic Mechanism for Severe Familial Hypercholesterolemia. The Canadian Journal Of Cardiology. 2018;34(10):1316-1324. PubMed |
| Zhang, Zhong; Wei, Teng-Fei; Zhao, Bei; Yin, Zhao; Shi, Quan-Xing; Liu, Pei-Lin; Liu, Li-Feng; Liu, Li; Zhao, Jing-Tao; Mao, Shuai; Rao, Meng-Meng; Wang, Shou-Li; Chen, Yun-Dai. Sex Differences Associated With Circulating PCSK9 in Patients Presenting With Acute Myocardial Infarction. Scientific Reports. 2019;9(1):3113. PubMed |
| Merrelaar, Anne; Buchtele, Nina; Schriefl, Christoph; Clodi, Christian; Poppe, Michael; Ettl, Florian; Herkner, Harald; Jilma, Bernd; Schwameis, Michael; Schoergenhofer, Christian. Low PCSK-9 levels Are Associated with Favorable Neurologic Function after Resuscitation from out of Hospital Cardiac Arrest. Journal Of Clinical Medicine. 2020;9(8) PubMed |
