Application: WB, IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921).
| Documents & Links for Anti WT1 mAb (Clone 5F2) | |
| Datasheet | Anti WT1 mAb (Clone 5F2) Datasheet |
| Vendor Page | Anti WT1 mAb (Clone 5F2) at CUSABIO |
| Documents & Links for Anti WT1 mAb (Clone 5F2) | |
| Datasheet | Anti WT1 mAb (Clone 5F2) Datasheet |
| Vendor Page | Anti WT1 mAb (Clone 5F2) |
