Anti VDAC1 mAb (Clone 3A1)

Catalog No:
CSB-RA025821A0HU-50
$210.00
Application: WB, IHC, ELISA 
Clonality: Monoclonal 
Purification: Purified - Affinity 
Reactivity: Human, Mouse, Rat 
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed:11845315, PubMed:18755977, PubMed:20230784, PubMed:8420959). May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (PubMed:15033708, PubMed:25296756).
Documents & Links for Anti VDAC1 mAb (Clone 3A1)
DatasheetAnti VDAC1 mAb (Clone 3A1) Datasheet
Vendor PageAnti VDAC1 mAb (Clone 3A1) at CUSABIO

Documents & Links for Anti VDAC1 mAb (Clone 3A1)
DatasheetAnti VDAC1 mAb (Clone 3A1) Datasheet
Vendor PageAnti VDAC1 mAb (Clone 3A1)