Microtubules are one of the components of the cytoskeleton, which performs essential and diverse functions within eukaryotic cells. Microtubules are composed of a heterodimer of alpha and beta tubulins. Tubulin is a GTP-binding protein, and extension and shortening of the microtubules are regulated by binding/hydrolysis of GTP.
Polyclonal Antibody of 100 µl targeting α-Tubulin for ICC, IP, WB.
| Product Specifications | |
| Application | ICC, IP, WB |
| Reactivity | Human, Mouse, Rat, Hamster, Chicken, Fruit fly |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Synthetic peptide N-terminal α-Tubulin |
| Gene ID - Human | |
| Gene ID - Mouse | |
| Formulation | 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Citations for Anti-α-Tubulin pAb – 29 Found |
| Geng, Yunyun; Monajembashi, Shamci; Shao, Anwen; Cui, Di; He, Weiyong; Chen, Zhongzhou; Hemmerich, Peter; Tang, Jun. Contribution of the C-terminal regions of promyelocytic leukemia protein (PML) isoforms II and V to PML nuclear body formation. The Journal Of Biological Chemistry. 2012;287(36):30729-42. PubMed - Comments: Used in: WB |
| Cao, J-X; Lu, Y; Qi, J-J; An, G-S; Mao, Z-B; Jia, H-T; Li, S-Y; Ni, J-H. MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells. Cell Death & Disease. 2014;5(9):e1426. PubMed - Comments: Used in: WB |
| Taniuchi, Keisuke; Furihata, Mutsuo; Saibara, Toshiji. KIF20A-mediated RNA granule transport system promotes the invasiveness of pancreatic cancer cells. Neoplasia (New York, N.y.). 2014;16(12):1082-93. PubMed - Comments: Used in: ICC |
| Horii, Takuro; Yamamoto, Masamichi; Morita, Sumiyo; Kimura, Mika; Nagao, Yasumitsu; Hatada, Izuho. p53 suppresses tetraploid development in mice. Scientific Reports. 2015;5:8907. PubMed - Comments: Used in: WB |
| Xu, Daichao; Zhang, Tao; Xiao, Juan; Zhu, Kezhou; Wei, Ran; Wu, Zheming; Meng, Huyan; Li, Ying; Yuan, Junying. Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon. Autophagy. 2015;11(4):617-28. PubMed - Comments: Used in: WB |
| Chinen, Takumi; Liu, Peng; Shioda, Shuya; Pagel, Judith; Cerikan, Berati; Lin, Tien-Chen; Gruss, Oliver; Hayashi, Yoshiki; Takeno, Haruka; Shima, Tomohiro; Okada, Yasushi; Hayakawa, Ichiro; Hayashi, Yoshio; Kigoshi, Hideo; Usui, Takeo; Schiebel, Elmar. The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle. Nature Communications. 2015;6:8722. PubMed - Comments: Used in: ICC |
| Xu, Daichao; Shan, Bing; Lee, Byung-Hoon; Zhu, Kezhou; Zhang, Tao; Sun, Huawang; Liu, Min; Shi, Linyu; Liang, Wei; Qian, Lihui; Xiao, Juan; Wang, Lili; Pan, Lifeng; Finley, Daniel; Yuan, Junying. Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system. Elife. 2015;4:e10510. PubMed - Comments: Used in: WB |
| Wang, Hui; Ma, Zaijun; Niu, Kongyan; Xiao, Yi; Wu, Xiaofen; Pan, Chenyu; Zhao, Yun; Wang, Kai; Zhang, Yaoyang; Liu, Nan. Antagonistic roles of Nibbler and Hen1 in modulating piRNA 3' ends in Drosophila. Development (Cambridge, England). 2016;143(3):530-9. PubMed - Comments: Used in: WB |
| Li, Hongmei; Hu, Chuansheng; Bai, Ling; Li, Hua; Li, Mingfa; Zhao, Xiaodong; Czajkowsky, Daniel M; Shao, Zhifeng. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Dna Research : An International Journal For Rapid Publication Of Reports On Genes And Genomes. 2016;23(6):571-580. PubMed - Comments: Used in: WB |
| Ma, Ke; Fu, Wan; Tang, Ming; Zhang, Chaohua; Hou, Tianyun; Li, Ran; Lu, Xiaopeng; Wang, Yanan; Zhou, Jingyi; Li, Xue; Zhang, Luyao; Wang, Lina; Zhao, Ying; Zhu, Wei-Guo. PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment. Autophagy. 2017;13(3):579-591. PubMed - Comments: Used in: ICC |
| Xu, Daichao; Liu, Jianping; Fu, Tao; Shan, Bing; Qian, Lihui; Pan, Lifeng; Yuan, Junying. USP25 regulates Wnt signaling by controlling the stability of tankyrases. Genes & Development. 2017;31(10):1024-1035. PubMed - Comments: Used in: WB |
| Shibutani, Mihiro; Horii, Takuro; Shoji, Hirotaka; Morita, Sumiyo; Kimura, Mika; Terawaki, Naomi; Miyakawa, Tsuyoshi; Hatada, Izuho. Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression and Autism-Related Behaviors in Mice. International Journal Of Molecular Sciences. 2017;18(9) PubMed - Comments: Used in: WB |
| Murakami, Akira; Nagao, Kohjiro; Juni, Naoto; Hara, Yuji; Umeda, Masato. An N-terminal di-proline motif is essential for fatty acid-dependent degradation of Δ9-desaturase in Drosophila. The Journal Of Biological Chemistry. 2017;292(49):19976-19986. PubMed - Comments: Used in: WB |
| Fu, Wan; Li, Xue; Lu, Xiaopeng; Zhang, Luyao; Li, Ran; Zhang, Nan; Liu, Shan; Yang, Xin; Wang, Yue; Zhao, Ying; Meng, Xiangbao; Zhu, Wei-Guo. A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells. Cell Death & Disease. 2017;8(10):e3086. PubMed - Comments: Used in: WB |
| Zhu, Kezhou; Liang, Wei; Ma, Zaijun; Xu, Daichao; Cao, Shuangyi; Lu, Xiaojuan; Liu, Nan; Shan, Bing; Qian, Lihui; Yuan, Junying. Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression. Cell Death & Disease. 2018;9(5):500. PubMed - Comments: Used in: WB |
| Makise, Masaki; Nakamura, Hideaki; Kuniyasu, Akihiko. The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype. Bmc Cancer. 2018;18(1):519. PubMed - Comments: Used in: WB |
| Sakane, Hiroshi; Akasaki, Kenji. The Major Lysosomal Membrane Proteins LAMP-1 and LAMP-2 Participate in Differentiation of C2C12 Myoblasts. Biological & Pharmaceutical Bulletin. 41(8):1186-1193. PubMed - Comments: Used in: WB |
| Ikawa, Keisuke; Sugimura, Kaoru. AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement. Nature Communications. 2018;9(1):3295. PubMed - Comments: Used in: WB |
| Sun, Xing; Duan, Yongjia; Qin, Caixia; Li, Jian-Chiuan; Duan, Gang; Deng, Xue; Ni, Jiangxia; Cao, Xu; Xiang, Ke; Tian, Kuili; Chen, Chun-Hong; Li, Ang; Fang, Yanshan. Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy. Cell Death & Disease. 2018;9(10):953. PubMed - Comments: Used in: WB |
| Cao, Ji-Xiang; Lu, Yao. Targeting CDC7 improves sensitivity to chemotherapy of esophageal squamous cell carcinoma. Oncotargets And Therapy. 12:63-74. PubMed - Comments: Used in: WB |
| Aoki, Tomoaki; Nishita, Michiru; Sonoda, Junya; Ikeda, Taro; Kakeji, Yoshihiro; Minami, Yasuhiro. Intraflagellar transport 20 promotes collective cancer cell invasion by regulating polarized organization of Golgi-associated microtubules. Cancer Science. 2019;110(4):1306-1316. PubMed - Comments: Used in: WB |
| Aoki, Tomoaki; Nishita, Michiru; Sonoda, Junya; Ikeda, Taro; Kakeji, Yoshihiro; Minami, Yasuhiro. Intraflagellar transport 20 promotes collective cancer cell invasion by regulating polarized organization of Golgi-associated microtubules. Cancer Science. 2019;110(4):1306-1316. PubMed - Comments: Used in: ICC |
| Yamada, Seiya; Sakakibara, Shin-Ichi. Expression profile of the STAND protein Nwd1 in the developing and mature mouse central nervous system. The Journal Of Comparative Neurology. 2018;526(13):2099-2114. PubMed - Comments: Used in: WB |
| Kanazawa, Takumi. Effect of Ovariectomy and Ovarian Hormone Administration on Hepatic Autophagy in Female Rats. Journal Of Nutritional Science And Vitaminology. 65(4):357-361. PubMed - Comments: Used in: WB |
| Kato, Hirofumi; Takayama-Ito, Mutsuyo; Iizuka-Shiota, Itoe; Fukushi, Shuetsu; Posadas-Herrera, Guillermo; Horiya, Madoka; Satoh, Masaaki; Yoshikawa, Tomoki; Yamada, Souichi; Harada, Shizuko; Fujii, Hikaru; Shibamura, Miho; Inagaki, Takuya; Morimoto, Kinjiro; Saijo, Masayuki; Lim, Chang-Kweng. Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in mice. Plos One. 14(10):e0223684. PubMed - Comments: Used in: WB |
| Tsuru, Emi; Oryu, Kohei; Sawada, Ken; Nishihara, Makoto; Tsuda, Masayuki. Complexin 2 regulates secretion of immunoglobulin in antibody-secreting cells. Immunity, Inflammation And Disease. 2019;7(4):318-325. PubMed - Comments: Used in: WB |
| Kamohara, Asana; Hirata, Hirohito; Xu, Xianghe; Shiraki, Makoto; Yamada, Sakuo; Zhang, Jing-Qi; Kukita, Toshio; Toyonaga, Kenji; Hara, Hiromitsu; Urano, Yasuteru; Yamashita, Yoshio; Miyamoto, Hiroshi; Kukita, Akiko. IgG immune complexes with Staphylococcus aureus protein A enhance osteoclast differentiation and bone resorption by stimulating Fc receptors and TLR2. International Immunology. 2020;32(2):89-104. PubMed - Comments: Used in: WB |
| Yamamoto, Yo-Hei; Kasai, Ayano; Omori, Hiroko; Takino, Tomoe; Sugihara, Munechika; Umemoto, Tetsuo; Hamasaki, Maho; Hatta, Tomohisa; Natsume, Tohru; Morimoto, Richard I; Arai, Ritsuko; Waguri, Satoshi; Sato, Miyuki; Sato, Ken; Bar-Nun, Shoshana; Yoshimori, Tamotsu; Noda, Takeshi; Nagata, Kazuhiro. ERdj8 governs the size of autophagosomes during the formation process. The Journal Of Cell Biology. 2020;219(8) PubMed - Comments: Used in: WB |
| Miki, Hirohito; Okito, Asuka; Akiyama, Masako; Ono, Takashi; Tachikawa, Noriko; Nakahama, Ken-Ichi. Genetic and epigenetic regulation of osteopontin by cyclic adenosine 3' 5'-monophosphate in osteoblasts. Gene. 2020;763:145059. PubMed - Comments: Used in: WB |