Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
| Product Specifications | |
| Application | WB, ELISA |
| Reactivity | Human, Mouse, Rat |
| Clonality | Monoclonal (Clone No.: 5G11) |
| Documents & Links for Anti TINF2 mAb (Clone 5G11) | |
| Datasheet | Anti TINF2 mAb (Clone 5G11) Datasheet |
| Vendor Page | Anti TINF2 mAb (Clone 5G11) at CUSABIO |
| Documents & Links for Anti TINF2 mAb (Clone 5G11) | |
| Datasheet | Anti TINF2 mAb (Clone 5G11) Datasheet |
| Vendor Page | Anti TINF2 mAb (Clone 5G11) |