Anti-SynCAM (TSLC1/CADM1) (Human) mAb (Clone: 3E1)

Catalog No:
MBL-CM004-3

Availability: 12PM PT on Dec. 3, 2024

Monoclonal antibody of 100 μg targeting SynCAM/TSLC1 for FCM, ICC, IHC, IPP, WB.

Product Specifications
Application FC, ICC, IP, WB, IHC
Reactivity Human, Mouse, Rat, Porcine, Equine
Clonality Monoclonal IgY
Host Chicken
Immunogen Recombinant fusion protein Fc-SynCAM
Gene ID - Human

23705

Gene ID - Mouse

54725

Formulation 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.

Citations for Anti-SynCAM (TSLC1/CADM1) (Human) mAb (Clone: 3E1) – 28 Found
Yang, Weidong; Kaur, Davinder; Okayama, Yoshimichi; Ito, Akihiko; Wardlaw, Andrew J; Brightling, Christopher E; Bradding, Peter. Human lung mast cells adhere to human airway smooth muscle, in part, via tumor suppressor in lung cancer-1. Journal Of Immunology (Baltimore, Md. : 1950). 2006;176(2):1238-43.  PubMed
Comments: Used in: FCM
Yang, Weidong; Kaur, Davinder; Okayama, Yoshimichi; Ito, Akihiko; Wardlaw, Andrew J; Brightling, Christopher E; Bradding, Peter. Human lung mast cells adhere to human airway smooth muscle, in part, via tumor suppressor in lung cancer-1. Journal Of Immunology (Baltimore, Md. : 1950). 2006;176(2):1238-43.  PubMed
Comments: Used in: ICC
Wakayama, Tomohiko; Sai, Yoshimichi; Ito, Akihiko; Kato, Yukio; Kurobo, Miho; Murakami, Yoshinori; Nakashima, Emi; Tsuji, Akira; Kitamura, Yukihiko; Iseki, Shoichi. Heterophilic binding of the adhesion molecules poliovirus receptor and immunoglobulin superfamily 4A in the interaction between mouse spermatogenic and Sertoli cells. Biology Of Reproduction. 2007;76(6):1081-90.  PubMed
Comments: Used in: ICC
Fogel, Adam I; Akins, Michael R; Krupp, Alexander J; Stagi, Massimiliano; Stein, Valentin; Biederer, Thomas. SynCAMs organize synapses through heterophilic adhesion. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 2007;27(46):12516-30.  PubMed
Comments: Used in: WB
Fogel, Adam I; Akins, Michael R; Krupp, Alexander J; Stagi, Massimiliano; Stein, Valentin; Biederer, Thomas. SynCAMs organize synapses through heterophilic adhesion. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 2007;27(46):12516-30.  PubMed
Comments: Used in: IP
Fujita, Eriko; Tanabe, Yuko; Hirose, Tomonori; Aurrand-Lions, Michel; Kasahara, Tadashi; Imhof, Beat A; Ohno, Shigeo; Momoi, Takashi. Loss of partitioning-defective-3/isotype-specific interacting protein (par-3/ASIP) in the elongating spermatid of RA175 (IGSF4A/SynCAM)-deficient mice. The American Journal Of Pathology. 2007;171(6):1800-10.  PubMed
Comments: Used in: IHC
Hollins, Fay; Kaur, Davinder; Yang, Weidong; Cruse, Glenn; Saunders, Ruth; Sutcliffe, Amanda; Berger, Patrick; Ito, Akihiko; Brightling, Christopher E; Bradding, Peter. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. Journal Of Immunology (Baltimore, Md. : 1950). 2008;181(4):2772-80.  PubMed
Comments: Used in: IP
Hollins, Fay; Kaur, Davinder; Yang, Weidong; Cruse, Glenn; Saunders, Ruth; Sutcliffe, Amanda; Berger, Patrick; Ito, Akihiko; Brightling, Christopher E; Bradding, Peter. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. Journal Of Immunology (Baltimore, Md. : 1950). 2008;181(4):2772-80.  PubMed
Comments: Used in: ICC
Hagiyama, Man; Ichiyanagi, Naoki; Kimura, Keiko B; Murakami, Yoshinori; Ito, Akihiko. Expression of a soluble isoform of cell adhesion molecule 1 in the brain and its involvement in directional neurite outgrowth. The American Journal Of Pathology. 2009;174(6):2278-89.  PubMed
Comments: Used in: WB
Hagiyama, Man; Ichiyanagi, Naoki; Kimura, Keiko B; Murakami, Yoshinori; Ito, Akihiko. Expression of a soluble isoform of cell adhesion molecule 1 in the brain and its involvement in directional neurite outgrowth. The American Journal Of Pathology. 2009;174(6):2278-89.  PubMed
Comments: Used in: IP
Hasstedt, Sandra J; Bezemer, Irene D; Callas, Peter W; Vossen, Carla Y; Trotman, Winifred; Hebbel, Robert P; Demers, Christine; Rosendaal, Frits R; Bovill, Edwin G. Cell adhesion molecule 1: a novel risk factor for venous thrombosis. Blood. 2009;114(14):3084-91.  PubMed
Comments: Used in: IHC
Gao, Ying; Lui, Wing-Yee. Transforming growth factor-β1 (TGF-β1) regulates cell junction restructuring via Smad-mediated repression and clathrin-mediated endocytosis of nectin-like molecule 2 (Necl-2). Plos One. 8(5):e64316.  PubMed
Comments: Used in: WB
Ribic, Adema; Liu, Xinran; Crair, Michael C; Biederer, Thomas. Structural organization and function of mouse photoreceptor ribbon synapses involve the immunoglobulin protein synaptic cell adhesion molecule 1. The Journal Of Comparative Neurology. 2014;522(4):900-20.  PubMed
Comments: Used in: WB
Ribic, Adema; Liu, Xinran; Crair, Michael C; Biederer, Thomas. Structural organization and function of mouse photoreceptor ribbon synapses involve the immunoglobulin protein synaptic cell adhesion molecule 1. The Journal Of Comparative Neurology. 2014;522(4):900-20.  PubMed
Comments: Used in: IHC
Nikitczuk, Jessica S; Patil, Shekhar B; Matikainen-Ankney, Bridget A; Scarpa, Joseph; Shapiro, Matthew L; Benson, Deanna L; Huntley, George W. N-cadherin regulates molecular organization of excitatory and inhibitory synaptic circuits in adult hippocampus in vivo. Hippocampus. 2014;24(8):943-962.  PubMed
Comments: Used in: WB
Cheadle, Lucas; Biederer, Thomas. Activity-dependent regulation of dendritic complexity by semaphorin 3A through Farp1. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 2014;34(23):7999-8009.  PubMed
Comments: Used in: WB
Zhang, Charles; Caldwell, Thomas A; Mirbolooki, M Reza; Duong, Diana; Park, Eun Jee; Chi, Nai-Wen; Chessler, Steven D. Extracellular CADM1 interactions influence insulin secretion by rat and human islet β-cells and promote clustering of syntaxin-1. American Journal Of Physiology. Endocrinology And Metabolism. 2016;310(11):E874-85.  PubMed
Comments: Used in: FCM
Park, Kellie A; Ribic, Adema; Laage Gaupp, Fabian M; Coman, Daniel; Huang, Yuegao; Dulla, Chris G; Hyder, Fahmeed; Biederer, Thomas. Excitatory Synaptic Drive and Feedforward Inhibition in the Hippocampal CA3 Circuit Are Regulated by SynCAM 1. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 2016;36(28):7464-75.  PubMed
Comments: Used in: IHC
Ziegler, Anja; Marti, Eliane; Summerfield, Artur; Baumann, Arnaud. Identification and characterization of equine blood plasmacytoid dendritic cells. Developmental And Comparative Immunology. 2016;65:352-357.  PubMed
Comments: Used in: FCM
Rademacher, Nils; Schmerl, Bettina; Lardong, Jennifer A; Wahl, Markus C; Shoichet, Sarah A. MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density. Scientific Reports. 2016;6:35283.  PubMed
Comments: Used in: ICC
Rathjen, Thomas; Yan, Xin; Kononenko, Natalia L; Ku, Min-Chi; Song, Kun; Ferrarese, Leiron; Tarallo, Valentina; Puchkov, Dmytro; Kochlamazashvili, Gaga; Brachs, Sebastian; Varela, Luis; Szigeti-Buck, Klara; Yi, Chun-Xia; Schriever, Sonja C; Tattikota, Sudhir Gopal; Carlo, Anne Sophie; Moroni, Mirko; Siemens, Jan; Heuser, Arnd; van der Weyden, Louise; Birkenfeld, Andreas L; Niendorf, Thoralf; Poulet, James F A; Horvath, Tamas L; Tschöp, Matthias H; Heinig, Matthias; Trajkovski, Mirko; Haucke, Volker; Poy, Matthew N. Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nature Neuroscience. 2017;20(8):1096-1103.  PubMed
Comments: Used in: WB
Rathjen, Thomas; Yan, Xin; Kononenko, Natalia L; Ku, Min-Chi; Song, Kun; Ferrarese, Leiron; Tarallo, Valentina; Puchkov, Dmytro; Kochlamazashvili, Gaga; Brachs, Sebastian; Varela, Luis; Szigeti-Buck, Klara; Yi, Chun-Xia; Schriever, Sonja C; Tattikota, Sudhir Gopal; Carlo, Anne Sophie; Moroni, Mirko; Siemens, Jan; Heuser, Arnd; van der Weyden, Louise; Birkenfeld, Andreas L; Niendorf, Thoralf; Poulet, James F A; Horvath, Tamas L; Tschöp, Matthias H; Heinig, Matthias; Trajkovski, Mirko; Haucke, Volker; Poy, Matthew N. Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nature Neuroscience. 2017;20(8):1096-1103.  PubMed
Comments: Used in: IHC
Braun, Roman Othmar; Python, Sylvie; Summerfield, Artur. Porcine B Cell Subset Responses to Toll-like Receptor Ligands. Frontiers In Immunology. 8:1044.  PubMed
Comments: Used in: FCM
Balan, Sreekumar; Arnold-Schrauf, Catharina; Abbas, Abdenour; Couespel, Norbert; Savoret, Juliette; Imperatore, Francesco; Villani, Alexandra-Chloé; Vu Manh, Thien-Phong; Bhardwaj, Nina; Dalod, Marc. Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity. Cell Reports. 2018;24(7):1902-1915.e6.  PubMed
Comments: Used in: FCM
Oka, Takashi; Mizuno, Hajime; Sakata, Masumi; Fujita, Hirofumi; Yoshino, Tadashi; Yamano, Yoshihisa; Utsumi, Kozo; Masujima, Tsutomu; Utsunomiya, Atae. Metabolic abnormalities in adult T-cell leukemia/lymphoma and induction of specific leukemic cell death using photodynamic therapy. Scientific Reports. 2018;8(1):14979.  PubMed
Comments: Used in: FCM
Parra-Sánchez, Héctor; Bustamante-Córdova, Lorena; Reséndiz, Mónica; Mata-Haro, Verónica; Pinelli-Saavedra, Araceli; Hernández, Jesús. Analysis of Swine Conventional Dendritic Cells, DEC205(+)CD172a(+/-)CADM1(+), from Blood and Spleen in Response to PRRSV and PEDV. Viruses. 2019;11(11)  PubMed
Comments: Used in: FCM
Nakahata, Shingo; Syahrul, Chilmi; Nakatake, Ayako; Sakamoto, Kuniyo; Yoshihama, Maki; Nishikata, Ichiro; Ukai, Yoshinori; Matsuura, Tadashi; Kameda, Takuro; Shide, Kotaro; Kubuki, Yoko; Hidaka, Tomonori; Kitanaka, Akira; Ito, Akihiko; Takemoto, Shigeki; Nakano, Nobuaki; Saito, Masumichi; Iwanaga, Masako; Sagara, Yasuko; Mochida, Kosuke; Amano, Masahiro; Maeda, Kouichi; Sueoka, Eisaburo; Okayama, Akihiko; Utsunomiya, Atae; Shimoda, Kazuya; Watanabe, Toshiki; Morishita, Kazuhiro. Clinical significance of soluble CADM1 as a novel marker for adult T-cell leukemia/lymphoma. Haematologica. 2021;106(2):532-542.  PubMed
Comments: Used in: ELISA
Bustamante-Córdova, Lorena; Melgoza-González, Edgar Alonso; Parra-Sánchez, Héctor; Reséndiz-Sandoval, Mónica; Burgara-Estrella, Alexel Jesús; Hernández, Jesús. Production of a full chimeric mouse x pig anti-porcine DEC205 receptor recombinant antibody. Journal Of Immunological Methods. 2021;489:112911.  PubMed
Comments: Used in: FCM