Application: WB, ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Protein Description: single-stranded DNA binding protein 1, mitochondrial
Gene Name: SSBP1
Alternative Gene Name: mtSSB, SSBP
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000029911: 92%, ENSRNOG00000012100: 89%
Entrez Gene ID: 6742
Uniprot ID: Q04837
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Protein Description: single-stranded DNA binding protein 1, mitochondrial
Gene Name: SSBP1
Alternative Gene Name: mtSSB, SSBP
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000029911: 92%, ENSRNOG00000012100: 89%
Entrez Gene ID: 6742
Uniprot ID: Q04837
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti SSBP1 pAb (ATL-HPA002866 w/enhanced validation) | |
| Antigen | PrEST Antigen SSBP1 (ATL-APrEST86624) |
| Documents & Links for Anti SSBP1 pAb (ATL-HPA002866 w/enhanced validation) | |
| Datasheet | Anti SSBP1 pAb (ATL-HPA002866 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti SSBP1 pAb (ATL-HPA002866 w/enhanced validation) at Atlas |
| Documents & Links for Anti SSBP1 pAb (ATL-HPA002866 w/enhanced validation) | |
| Datasheet | Anti SSBP1 pAb (ATL-HPA002866 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti SSBP1 pAb (ATL-HPA002866 w/enhanced validation) |
| Citations for Anti SSBP1 pAb (ATL-HPA002866 w/enhanced validation) – 11 Found |
| The mitochondrial outer-membrane location of the EXD2 exonuclease contradicts its direct role in nuclear DNA repair. Sci Rep. 2018 Mar 29;8(1):5368. doi: 10.1038/s41598-018-23690-y. PubMed |
| Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res. 2018 Jul 27;46(13):6642-6669. doi: 10.1093/nar/gky456. PubMed |
| Impaired Mitochondrial Fatty Acid Synthesis Leads to Neurodegeneration in Mice. J Neurosci. 2018 Nov 7;38(45):9781-9800. doi: 10.1523/JNEUROSCI.3514-17.2018. Epub 2018 Sep 28. PubMed |
| Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer. Neoplasia. 2019 Apr;21(4):353-362. doi: 10.1016/j.neo.2019.01.002. Epub 2019 Mar 8. PubMed |
| Mitochondrial fusion is required for regulation of mitochondrial DNA replication. PLoS Genet. 2019 Jun 6;15(6):e1008085. doi: 10.1371/journal.pgen.1008085. eCollection 2019 Jun. PubMed |
| Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis. Nat Commun. 2022 Apr 29;13(1):2340. doi: 10.1038/s41467-022-29945-7. PubMed |
| Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments. J Virol. 2010 Sep;84(17):8871-87. doi: 10.1128/JVI.00725-10. Epub 2010 Jun 23. PubMed |
| Whole cell formaldehyde cross-linking simplifies purification of mitochondrial nucleoids and associated proteins involved in mitochondrial gene expression. PLoS One. 2015 Feb 19;10(2):e0116726. doi: 10.1371/journal.pone.0116726. eCollection 2015. PubMed |
| Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB. Nucleic Acids Res. 2019 Apr 23;47(7):3680-3698. doi: 10.1093/nar/gkz047. PubMed |
| Dominant mutations in mtDNA maintenance gene SSBP1 cause optic atrophy and foveopathy. J Clin Invest. 2020 Jan 2;130(1):143-156. doi: 10.1172/JCI128513. PubMed |
| Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells. Cell Metab. 2019 Feb 5;29(2):399-416.e10. doi: 10.1016/j.cmet.2018.10.014. Epub 2018 Nov 15. PubMed |