Application: IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: solute carrier family 22 (organic cation transporter), member 2
Gene Name: SLC22A2
Alternative Gene Name: OCT2
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000040966: 84%, ENSRNOG00000016625: 77%
Entrez Gene ID: 6582
Uniprot ID: O15244
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: solute carrier family 22 (organic cation transporter), member 2
Gene Name: SLC22A2
Alternative Gene Name: OCT2
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000040966: 84%, ENSRNOG00000016625: 77%
Entrez Gene ID: 6582
Uniprot ID: O15244
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti SLC22A2 pAb (ATL-HPA008567 w/enhanced validation) | |
| Antibody | Anti SLC22A2 pAb (ATL-HPA008549 w/enhanced validation) |
| Antigen | PrEST Antigen SLC22A2 (ATL-APrEST86074) |
| Documents & Links for Anti SLC22A2 pAb (ATL-HPA008567 w/enhanced validation) | |
| Datasheet | Anti SLC22A2 pAb (ATL-HPA008567 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti SLC22A2 pAb (ATL-HPA008567 w/enhanced validation) at Atlas |
| Documents & Links for Anti SLC22A2 pAb (ATL-HPA008567 w/enhanced validation) | |
| Datasheet | Anti SLC22A2 pAb (ATL-HPA008567 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti SLC22A2 pAb (ATL-HPA008567 w/enhanced validation) |
| Citations for Anti SLC22A2 pAb (ATL-HPA008567 w/enhanced validation) – 7 Found |
| Metformin Accumulation Correlates with Organic Cation Transporter 2 Protein Expression and Predicts Mammary Tumor Regression In Vivo. Cancer Prev Res (Phila). 2017 Mar;10(3):198-207. doi: 10.1158/1940-6207.CAPR-16-0211-T. Epub 2017 Feb 2. PubMed |
| Direct effects of metformin in the endometrium: a hypothetical mechanism for the treatment of women with PCOS and endometrial carcinoma. J Exp Clin Cancer Res. 2014 May 11;33(1):41. doi: 10.1186/1756-9966-33-41. PubMed |
| Reversing the reduced level of endometrial GLUT4 expression in polycystic ovary syndrome: a mechanistic study of metformin action. Am J Transl Res. 2015 Mar 15;7(3):574-86. eCollection 2015. PubMed |
| Upregulation of miR-489-3p and miR-630 inhibits oxaliplatin uptake in renal cell carcinoma by targeting OCT2. Acta Pharm Sin B. 2019 Sep;9(5):1008-1020. doi: 10.1016/j.apsb.2019.01.002. Epub 2019 Jan 8. PubMed |
| The failure of DAC to induce OCT2 expression and its remission by hemoglobin-based nanocarriers under hypoxia in renal cell carcinoma. Theranostics. 2020 Feb 18;10(8):3562-3578. doi: 10.7150/thno.39944. eCollection 2020. PubMed |
| Farnesoid X Receptor Activation Stimulates Organic Cations Transport in Human Renal Proximal Tubular Cells. Int J Mol Sci. 2020 Aug 24;21(17):6078. doi: 10.3390/ijms21176078. PubMed |
| Exacerbation of Cisplatin Cellular Toxicity by Regulation of the Human Organic Cation Transporter 2 through Angiotensin II. Int J Mol Sci. 2022 Dec 14;23(24):15866. doi: 10.3390/ijms232415866. PubMed |