Application: WB, IHC, IF, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity).
| Documents & Links for Anti SIN3A mAb (Clone 10G3) | |
| Datasheet | Anti SIN3A mAb (Clone 10G3) Datasheet |
| Vendor Page | Anti SIN3A mAb (Clone 10G3) at CUSABIO |
| Documents & Links for Anti SIN3A mAb (Clone 10G3) | |
| Datasheet | Anti SIN3A mAb (Clone 10G3) Datasheet |
| Vendor Page | Anti SIN3A mAb (Clone 10G3) |
