Application: IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: ryanodine receptor 2 (cardiac)
Gene Name: RYR2
Alternative Gene Name: ARVC2, ARVD2, VTSIP
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000021313: 95%, ENSRNOG00000017060: 92%
Entrez Gene ID: 6262
Uniprot ID: Q92736
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: ryanodine receptor 2 (cardiac)
Gene Name: RYR2
Alternative Gene Name: ARVC2, ARVD2, VTSIP
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000021313: 95%, ENSRNOG00000017060: 92%
Entrez Gene ID: 6262
Uniprot ID: Q92736
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti RYR2 pAb (ATL-HPA020028 w/enhanced validation) | |
| Antigen | PrEST Antigen RYR2 (ATL-APrEST73317) |
| Documents & Links for Anti RYR2 pAb (ATL-HPA020028 w/enhanced validation) | |
| Datasheet | Anti RYR2 pAb (ATL-HPA020028 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti RYR2 pAb (ATL-HPA020028 w/enhanced validation) at Atlas |
| Documents & Links for Anti RYR2 pAb (ATL-HPA020028 w/enhanced validation) | |
| Datasheet | Anti RYR2 pAb (ATL-HPA020028 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti RYR2 pAb (ATL-HPA020028 w/enhanced validation) |
| Citations for Anti RYR2 pAb (ATL-HPA020028 w/enhanced validation) – 11 Found |
| Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation. Biomaterials. 2015 Aug;60:82-91. doi: 10.1016/j.biomaterials.2015.03.055. Epub 2015 May 15. PubMed |
| Loss of CASK Accelerates Heart Failure Development. Circ Res. 2021 Apr 16;128(8):1139-1155. doi: 10.1161/CIRCRESAHA.120.318170. Epub 2021 Feb 17. PubMed |
| Axial Tubule Junctions Activate Atrial Ca(2+) Release Across Species. Front Physiol. 2018 Oct 8;9:1227. doi: 10.3389/fphys.2018.01227. eCollection 2018. PubMed |
| Junctophilin-2 tethers T-tubules and recruits functional L-type calcium channels to lipid rafts in adult cardiomyocytes. Cardiovasc Res. 2021 Jan 1;117(1):149-161. doi: 10.1093/cvr/cvaa033. PubMed |
| IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency. Front Cell Dev Biol. 2020 Aug 12;8:772. doi: 10.3389/fcell.2020.00772. eCollection 2020. PubMed |
| Long-term effects of empagliflozin on excitation-contraction-coupling in human induced pluripotent stem cell cardiomyocytes. J Mol Med (Berl). 2020 Dec;98(12):1689-1700. doi: 10.1007/s00109-020-01989-6. Epub 2020 Oct 9. PubMed |
| Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes. STAR Protoc. 2020 Jun 3;1(1):100026. doi: 10.1016/j.xpro.2020.100026. eCollection 2020 Jun 19. PubMed |
| Human Atrial Fibrillation Is Not Associated With Remodeling of Ryanodine Receptor Clusters. Front Cell Dev Biol. 2021 Feb 25;9:633704. doi: 10.3389/fcell.2021.633704. eCollection 2021. PubMed |
| Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT(1)-fragment domains in cardiomyocytes. Sci Rep. 2022 Jun 20;12(1):10387. doi: 10.1038/s41598-022-14320-9. PubMed |
| Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function. Nat Commun. 2022 Nov 4;13(1):6663. doi: 10.1038/s41467-022-34366-7. PubMed |
| CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2. Circ Res. 2023 Feb 17;132(4):400-414. doi: 10.1161/CIRCRESAHA.122.322031. Epub 2023 Jan 30. PubMed |