Application: WB
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: RanBP-type and C3HC4-type zinc finger containing 1
Gene Name: RBCK1
Alternative Gene Name: C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000027466: 87%, ENSRNOG00000006695: 88%
Entrez Gene ID: 10616
Uniprot ID: Q9BYM8
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: RanBP-type and C3HC4-type zinc finger containing 1
Gene Name: RBCK1
Alternative Gene Name: C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000027466: 87%, ENSRNOG00000006695: 88%
Entrez Gene ID: 10616
Uniprot ID: Q9BYM8
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti RBCK1 pAb (ATL-HPA024185 w/enhanced validation) | |
| Antigen | PrEST Antigen RBCK1 (ATL-APrEST86460) |
| Documents & Links for Anti RBCK1 pAb (ATL-HPA024185 w/enhanced validation) | |
| Datasheet | Anti RBCK1 pAb (ATL-HPA024185 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti RBCK1 pAb (ATL-HPA024185 w/enhanced validation) at Atlas |
| Documents & Links for Anti RBCK1 pAb (ATL-HPA024185 w/enhanced validation) | |
| Datasheet | Anti RBCK1 pAb (ATL-HPA024185 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti RBCK1 pAb (ATL-HPA024185 w/enhanced validation) |
| Citations for Anti RBCK1 pAb (ATL-HPA024185 w/enhanced validation) – 6 Found |
| Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3481-E3489. doi: 10.1073/pnas.1702367114. Epub 2017 Apr 12. PubMed |
| HOIL-1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation. EMBO J. 2022 Apr 19;41(8):e109700. doi: 10.15252/embj.2021109700. Epub 2022 Mar 11. PubMed |
| UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases. Am J Hum Genet. 2015 Feb 5;96(2):221-34. doi: 10.1016/j.ajhg.2014.12.024. Epub 2015 Jan 29. PubMed |
| The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nat Commun. 2015 Nov 3;6:8777. doi: 10.1038/ncomms9777. PubMed |
| Shigella flexneri suppresses NF-κB activation by inhibiting linear ubiquitin chain ligation. Nat Microbiol. 2016 May 27;1(7):16084. doi: 10.1038/nmicrobiol.2016.84. PubMed |
| Targeting BCL10 by small peptides for the treatment of B cell lymphoma. Theranostics. 2020 Sep 19;10(25):11622-11636. doi: 10.7150/thno.47533. eCollection 2020. PubMed |