Application: WB, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: POU class 2 homeobox 3
Gene Name: POU2F3
Alternative Gene Name: Epoc-1, OCT11, PLA-1, Skn-1a
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000032015: 86%, ENSRNOG00000009118: 84%
Entrez Gene ID: 25833
Uniprot ID: Q9UKI9
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: POU class 2 homeobox 3
Gene Name: POU2F3
Alternative Gene Name: Epoc-1, OCT11, PLA-1, Skn-1a
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000032015: 86%, ENSRNOG00000009118: 84%
Entrez Gene ID: 25833
Uniprot ID: Q9UKI9
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti POU2F3 pAb (ATL-HPA019652 w/enhanced validation) | |
| Antigen | PrEST Antigen POU2F3 (ATL-APrEST86702) |
| Documents & Links for Anti POU2F3 pAb (ATL-HPA019652 w/enhanced validation) | |
| Datasheet | Anti POU2F3 pAb (ATL-HPA019652 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti POU2F3 pAb (ATL-HPA019652 w/enhanced validation) at Atlas |
| Documents & Links for Anti POU2F3 pAb (ATL-HPA019652 w/enhanced validation) | |
| Datasheet | Anti POU2F3 pAb (ATL-HPA019652 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti POU2F3 pAb (ATL-HPA019652 w/enhanced validation) |
| Citations for Anti POU2F3 pAb (ATL-HPA019652 w/enhanced validation) – 7 Found |
| MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate. Cancer Cell. 2020 Jul 13;38(1):60-78.e12. doi: 10.1016/j.ccell.2020.05.001. Epub 2020 May 30. PubMed |
| ASCL1 represses a SOX9(+) neural crest stem-like state in small cell lung cancer. Genes Dev. 2021 Jun;35(11-12):847-869. doi: 10.1101/gad.348295.121. Epub 2021 May 20. PubMed |
| POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. Genes Dev. 2018 Jul 1;32(13-14):915-928. doi: 10.1101/gad.314815.118. Epub 2018 Jun 26. PubMed |
| An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. Elife. 2021 Apr 6;10:e66788. doi: 10.7554/eLife.66788. PubMed |
| OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature. 2022 Jul;607(7917):169-175. doi: 10.1038/s41586-022-04842-7. Epub 2022 May 16. PubMed |
| Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair. Elife. 2022 Sep 8;11:e78074. doi: 10.7554/eLife.78074. PubMed |
| Contribution of Trp63(CreERT2)-labeled cells to alveolar regeneration is independent of tuft cells. Elife. 2022 Sep 21;11:e78217. doi: 10.7554/eLife.78217. PubMed |