Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]

Catalog No:
CAC-TIP-PTD-P07
$679.00

Format: Ammonium sulfate precipitated serum (Ig fraction) in 50% glycerol with azide preservative. Prepared from fresh rabbits immunized with a peptide identical to the very popular, but sold out, CAC-TIP-PTD-PO1 that was sold as diluted serum.

Catalog numbers beginning with "CAC" are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.

TDP-43, a heterogeneous nuclear ribonucleoprotein, was identified as a component of ubiquitin-positive and tau-negative inclusions observed in cases of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). Immunochemical analyses using antibodies generated against phospho- and non-phosphopeptides of human TDP-43 revealed that abnormally phosphorylated full-length TDP-43 (45 kDa), C-terminal fragments (~25 kDa) and smearing substances are deposited as intracellular inclusions in affected regions of FTLD-U and ALS cases.

These antibodies are powerful tools for biochemical and immunohistochemical analyses of neurodegenerative diseases and for evaluation of cellular or animal models of TDP-43 proteinopathy.



Product Specifications
Application WB, IHC, ELISA
Reactivity Human
Clonality Polyclonal
Host Rabbit

Documents & Links for Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]
Datasheet Anti phospho TDP-43 (pS409/410) pAb Datasheet
Vendor Page Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01] at Cosmo Bio LTD

Documents & Links for Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]
Datasheet Anti phospho TDP-43 (pS409/410) pAb Datasheet
Vendor Page Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]