Monoclonal antibody Phospho-p62 (SQSTM1) (Ser403) of 100 µl targeting for IHC, WB.
| Product Specifications | |
| Application | WB, IHC |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal IgG2a ĸ |
| Host | Rat |
| Immunogen | synthetic peptide CKKKESLSQMLpSMGFSDEGKKK (corresponding to amino acid residues 396-410 of human p62 (SQSTM1)) |
| Gene ID - Human | |
| Formulation | PBS/50% glycerol, pH 7.2 |
| Citations for Anti-Phospho-p62 (SQSTM1) (Ser403) mAb (Clone: 4F6) – 5 Found |
| Matsumoto, Gen; Wada, Koji; Okuno, Misako; Kurosawa, Masaru; Nukina, Nobuyuki. Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins. Molecular Cell. 2011;44(2):279-89. PubMed - Comments: Used in: WB |
| Matsumoto, Gen; Wada, Koji; Okuno, Misako; Kurosawa, Masaru; Nukina, Nobuyuki. Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins. Molecular Cell. 2011;44(2):279-89. PubMed - Comments: Used in: IHC |
| Kurosawa, Masaru; Matsumoto, Gen; Kino, Yoshihiro; Okuno, Misako; Kurosawa-Yamada, Mizuki; Washizu, Chika; Taniguchi, Harumi; Nakaso, Kazuhiro; Yanagawa, Toru; Warabi, Eiji; Shimogori, Tomomi; Sakurai, Takashi; Hattori, Nobutaka; Nukina, Nobuyuki. Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice. Human Molecular Genetics. 2015;24(4):1092-105. PubMed - Comments: Used in: IHC |
| Yamada, Mami; Iwata, Masahiro; Warabi, Eiji; Oishi, Hisashi; Lira, Vitor A; Okutsu, Mitsuharu. p62/SQSTM1 and Nrf2 are essential for exercise-mediated enhancement of antioxidant protein expression in oxidative muscle. Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology. 2019;33(7):8022-8032. PubMed - Comments: Used in: WB |
| Kanai, Tomotake; Kondo, Naoki; Okada, Masayasu; Sano, Hiroshige; Okumura, Go; Kijima, Yasufumi; Ogose, Akira; Kawashima, Hiroyuki; Endo, Naoto. The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3. Journal Of Orthopaedic Surgery And Research. 2020;15(1):87. PubMed - Comments: Used in: WB |