Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
| Product Specifications | |
| Application | IHC, ELISA |
| Reactivity | Human |
| Clonality | Monoclonal (Clone No.: 4A6) |
| Documents & Links for Anti Phospho-MLKL (S358) mAb (Clone 4A6) | |
| Datasheet | Anti Phospho-MLKL (S358) mAb (Clone 4A6) Datasheet |
| Vendor Page | Anti Phospho-MLKL (S358) mAb (Clone 4A6) at CUSABIO |
| Documents & Links for Anti Phospho-MLKL (S358) mAb (Clone 4A6) | |
| Datasheet | Anti Phospho-MLKL (S358) mAb (Clone 4A6) Datasheet |
| Vendor Page | Anti Phospho-MLKL (S358) mAb (Clone 4A6) |