Application: WB, IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
| Documents & Links for Anti Phospho-FOXO3 (S253) mAb (Clone 1E1) | |
| Datasheet | Anti Phospho-FOXO3 (S253) mAb (Clone 1E1) Datasheet |
| Vendor Page | Anti Phospho-FOXO3 (S253) mAb (Clone 1E1) at CUSABIO |
| Documents & Links for Anti Phospho-FOXO3 (S253) mAb (Clone 1E1) | |
| Datasheet | Anti Phospho-FOXO3 (S253) mAb (Clone 1E1) Datasheet |
| Vendor Page | Anti Phospho-FOXO3 (S253) mAb (Clone 1E1) |