Application: WB, IF, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation (PubMed:9637683, PubMed:11175748, PubMed:12637535). The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis (PubMed:24508390).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation (PubMed:9637683, PubMed:11175748, PubMed:12637535). The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis (PubMed:24508390).
| Documents & Links for Anti Phospho-ERN1 (S724) mAb (Clone 1F12) | |
| Datasheet | Anti Phospho-ERN1 (S724) mAb (Clone 1F12) Datasheet |
| Vendor Page | Anti Phospho-ERN1 (S724) mAb (Clone 1F12) at CUSABIO |
| Documents & Links for Anti Phospho-ERN1 (S724) mAb (Clone 1F12) | |
| Datasheet | Anti Phospho-ERN1 (S724) mAb (Clone 1F12) Datasheet |
| Vendor Page | Anti Phospho-ERN1 (S724) mAb (Clone 1F12) |