Application: WB, IHC, IF, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
| Documents & Links for Anti Phospho-EIF2S1 (S51) mAb (Clone 1C6) | |
| Datasheet | Anti Phospho-EIF2S1 (S51) mAb (Clone 1C6) Datasheet |
| Vendor Page | Anti Phospho-EIF2S1 (S51) mAb (Clone 1C6) at CUSABIO |
| Documents & Links for Anti Phospho-EIF2S1 (S51) mAb (Clone 1C6) | |
| Datasheet | Anti Phospho-EIF2S1 (S51) mAb (Clone 1C6) Datasheet |
| Vendor Page | Anti Phospho-EIF2S1 (S51) mAb (Clone 1C6) |