Application: IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Protein Description: Purkinje cell protein 4
Gene Name: PCP4
Alternative Gene Name: PEP-19
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000000159: 96%, ENSRNOG00000001628: 96%
Entrez Gene ID: 5121
Uniprot ID: P48539
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Protein Description: Purkinje cell protein 4
Gene Name: PCP4
Alternative Gene Name: PEP-19
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000000159: 96%, ENSRNOG00000001628: 96%
Entrez Gene ID: 5121
Uniprot ID: P48539
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti PCP4 pAb (ATL-HPA005792 w/enhanced validation) | |
| Antigen | PrEST Antigen PCP4 (ATL-APrEST70287) |
| Documents & Links for Anti PCP4 pAb (ATL-HPA005792 w/enhanced validation) | |
| Datasheet | Anti PCP4 pAb (ATL-HPA005792 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti PCP4 pAb (ATL-HPA005792 w/enhanced validation) at Atlas |
| Documents & Links for Anti PCP4 pAb (ATL-HPA005792 w/enhanced validation) | |
| Datasheet | Anti PCP4 pAb (ATL-HPA005792 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti PCP4 pAb (ATL-HPA005792 w/enhanced validation) |
| Citations for Anti PCP4 pAb (ATL-HPA005792 w/enhanced validation) – 33 Found |
| Structural development and dorsoventral maturation of the medial entorhinal cortex. Elife. 2016 Apr 2;5:e13343. doi: 10.7554/eLife.13343. PubMed |
| The Dendrites of CA2 and CA1 Pyramidal Neurons Differentially Regulate Information Flow in the Cortico-Hippocampal Circuit. J Neurosci. 2017 Mar 22;37(12):3276-3293. doi: 10.1523/JNEUROSCI.2219-16.2017. Epub 2017 Feb 17. PubMed |
| Entorhinal-CA3 Dual-Input Control of Spike Timing in the Hippocampus by Theta-Gamma Coupling. Neuron. 2017 Mar 8;93(5):1213-1226.e5. doi: 10.1016/j.neuron.2017.02.017. PubMed |
| Complementary Modular Microcircuits of the Rat Medial Entorhinal Cortex. Front Syst Neurosci. 2017 Apr 10;11:20. doi: 10.3389/fnsys.2017.00020. eCollection 2017. PubMed |
| A circuit from hippocampal CA2 to lateral septum disinhibits social aggression. Nature. 2018 Dec;564(7735):213-218. doi: 10.1038/s41586-018-0772-0. Epub 2018 Dec 5. PubMed |
| Proximodistal Organization of the CA2 Hippocampal Area. Cell Rep. 2019 Feb 12;26(7):1734-1746.e6. doi: 10.1016/j.celrep.2019.01.060. PubMed |
| Complement-associated loss of CA2 inhibitory synapses in the demyelinated hippocampus impairs memory. Acta Neuropathol. 2021 Oct;142(4):643-667. doi: 10.1007/s00401-021-02338-8. Epub 2021 Jun 25. PubMed |
| Combinatorial actions of glucocorticoid and mineralocorticoid stress hormone receptors are required for preventing neurodegeneration of the mouse hippocampus. Neurobiol Stress. 2021 Jul 21;15:100369. doi: 10.1016/j.ynstr.2021.100369. eCollection 2021 Nov. PubMed |
| Anterograde transneuronal tracing and genetic control with engineered yellow fever vaccine YFV-17D. Nat Methods. 2021 Dec;18(12):1542-1551. doi: 10.1038/s41592-021-01319-9. Epub 2021 Nov 25. PubMed |
| Laminar Organization of the Entorhinal Cortex in Macaque Monkeys Based on Cell-Type-Specific Markers and Connectivity. Front Neural Circuits. 2021 Dec 7;15:790116. doi: 10.3389/fncir.2021.790116. eCollection 2021. PubMed |
| Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits. Nat Neurosci. 2014 Feb;17(2):269-79. doi: 10.1038/nn.3614. Epub 2013 Dec 15. PubMed |
| The hippocampal CA2 region is essential for social memory. Nature. 2014 Apr 3;508(7494):88-92. doi: 10.1038/nature13028. Epub 2014 Feb 23. PubMed |
| Distribution of interneurons in the CA2 region of the rat hippocampus. Front Neuroanat. 2014 Sep 26;8:104. doi: 10.3389/fnana.2014.00104. eCollection 2014. PubMed |
| DACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretion. Hypertension. 2015 May;65(5):1103-10. doi: 10.1161/HYP.0000000000000025. Epub 2015 Mar 16. PubMed |
| Determinants of different deep and superficial CA1 pyramidal cell dynamics during sharp-wave ripples. Nat Neurosci. 2015 Sep;18(9):1281-1290. doi: 10.1038/nn.4074. Epub 2015 Jul 27. PubMed |
| Altered Oscillatory Dynamics of CA1 Parvalbumin Basket Cells during Theta-Gamma Rhythmopathies of Temporal Lobe Epilepsy. eNeuro. 2016 Nov 18;3(6):ENEURO.0284-16.2016. doi: 10.1523/ENEURO.0284-16.2016. eCollection 2016 Nov-Dec. PubMed |
| Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory. Neuron. 2017 Aug 30;95(5):1089-1102.e5. doi: 10.1016/j.neuron.2017.07.036. Epub 2017 Aug 17. PubMed |
| The subiculum is a patchwork of discrete subregions. Elife. 2018 Oct 30;7:e37701. doi: 10.7554/eLife.37701. PubMed |
| Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription. Cell. 2019 Aug 22;178(5):1159-1175.e17. doi: 10.1016/j.cell.2019.07.043. PubMed |
| Upregulation of PCP4 in human aldosterone-producing adenomas fosters human adrenocortical tumor cell growth via AKT and AMPK pathway. Int J Clin Exp Pathol. 2018 Mar 1;11(3):1197-1207. eCollection 2018. PubMed |
| Structural Correlates of CA2 and CA3 Pyramidal Cell Activity in Freely-Moving Mice. J Neurosci. 2020 Jul 22;40(30):5797-5806. doi: 10.1523/JNEUROSCI.0099-20.2020. Epub 2020 Jun 18. PubMed |
| Hippocampal CA2 sharp-wave ripples reactivate and promote social memory. Nature. 2020 Nov;587(7833):264-269. doi: 10.1038/s41586-020-2758-y. Epub 2020 Sep 23. PubMed |
| Species-specific differences in synaptic transmission and plasticity. Sci Rep. 2020 Oct 6;10(1):16557. doi: 10.1038/s41598-020-73547-6. PubMed |
| Newborn mice form lasting CA2-dependent memories of their mothers. Cell Rep. 2021 Jan 26;34(4):108668. doi: 10.1016/j.celrep.2020.108668. PubMed |
| Postnatal Developmental Expression Profile Classifies the Indusium Griseum as a Distinct Subfield of the Hippocampal Formation. Front Cell Dev Biol. 2021 Jan 12;8:615571. doi: 10.3389/fcell.2020.615571. eCollection 2020. PubMed |
| Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex. Elife. 2021 Mar 26;10:e67262. doi: 10.7554/eLife.67262. PubMed |
| An update to Hippocampome.org by integrating single-cell phenotypes with circuit function in vivo. PLoS Biol. 2021 May 6;19(5):e3001213. doi: 10.1371/journal.pbio.3001213. eCollection 2021 May. PubMed |
| Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory. Mol Psychiatry. 2022 Jun;27(6):2879-2900. doi: 10.1038/s41380-021-01124-y. Epub 2021 May 14. PubMed |
| Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1. Elife. 2021 May 18;10:e63352. doi: 10.7554/eLife.63352. PubMed |
| Optical Fiber-Based Recording of Climbing Fiber Ca(2+) Signals in Freely Behaving Mice. Biology (Basel). 2022 Jun 13;11(6):907. doi: 10.3390/biology11060907. PubMed |
| A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. Cell. 2022 Sep 1;185(18):3390-3407.e18. doi: 10.1016/j.cell.2022.07.026. PubMed |
| Robust information routing by dorsal subiculum neurons. Sci Adv. 2021 Mar 10;7(11):eabf1913. doi: 10.1126/sciadv.abf1913. Print 2021 Mar. PubMed |
| Organization of hippocampal CA3 into correlated cell assemblies supports a stable spatial code. Cell Rep. 2023 Feb 28;42(2):112119. doi: 10.1016/j.celrep.2023.112119. Epub 2023 Feb 17. PubMed |