Application: WB, ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: poly (ADP-ribose) polymerase 1
Gene Name: PARP1
Alternative Gene Name: ADPRT, PARP, PPOL
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000026496: 95%, ENSRNOG00000003084: 94%
Entrez Gene ID: 142
Uniprot ID: P09874
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: poly (ADP-ribose) polymerase 1
Gene Name: PARP1
Alternative Gene Name: ADPRT, PARP, PPOL
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000026496: 95%, ENSRNOG00000003084: 94%
Entrez Gene ID: 142
Uniprot ID: P09874
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti PARP1 pAb (ATL-HPA045168 w/enhanced validation) | |
| Antigen | PrEST Antigen PARP1 (ATL-APrEST71075) |
| Documents & Links for Anti PARP1 pAb (ATL-HPA045168 w/enhanced validation) | |
| Datasheet | Anti PARP1 pAb (ATL-HPA045168 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti PARP1 pAb (ATL-HPA045168 w/enhanced validation) at Atlas |
| Documents & Links for Anti PARP1 pAb (ATL-HPA045168 w/enhanced validation) | |
| Datasheet | Anti PARP1 pAb (ATL-HPA045168 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti PARP1 pAb (ATL-HPA045168 w/enhanced validation) |
| Citations for Anti PARP1 pAb (ATL-HPA045168 w/enhanced validation) – 7 Found |
| Poly (ADP-Ribose) Polymerase 1 Mediated Arginase II Activation Is Responsible for Oxidized LDL-Induced Endothelial Dysfunction. Front Pharmacol. 2018 Aug 15;9:882. doi: 10.3389/fphar.2018.00882. eCollection 2018. PubMed |
| YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo-/radio-resistance by suppressing caspase-mediated apoptosis. J Pathol. 2019 Aug;248(4):476-487. doi: 10.1002/path.5274. Epub 2019 Apr 29. PubMed |
| [(18)F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging. Mol Imaging Biol. 2020 Oct;22(5):1226-1234. doi: 10.1007/s11307-020-01497-6. PubMed |
| NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers. Sci Adv. 2021 Sep 17;7(38):eabc8145. doi: 10.1126/sciadv.abc8145. Epub 2021 Sep 15. PubMed |
| Correlation between molar activity, injection mass and uptake of the PARP targeting radiotracer [(18)F]olaparib in mouse models of glioma. EJNMMI Res. 2022 Oct 9;12(1):67. doi: 10.1186/s13550-022-00940-9. PubMed |
| Poly ADP-ribosylation of SET8 leads to aberrant H4K20 methylation in mammalian nuclear genome. Commun Biol. 2022 Nov 25;5(1):1292. doi: 10.1038/s42003-022-04241-8. PubMed |
| Depletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies. Nucleic Acids Res. 2023 Feb 22;51(3):1297-1316. doi: 10.1093/nar/gkac1237. PubMed |