This antibody is validated for multiple applications (WB, IHC, ICC and IP) and is widely cited, including in research papers with more than 200 citations (Waguri S, Komatsu M. Biochemical and morphological detection of inclusion bodies in autophagy-deficient mice. Methods Enzymol. 453, 181-96 (2009)). This is a polyclonal antibody of 100 μl that is raised in rabbit and is reactive with human, hamster, mouse, rat.
| Product Specifications | |
| Application | ICC, IP, WB, IHC |
| Reactivity | Human, Mouse, Rat, Hamster, Zebrafish, Bovine |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant human p62 (120-440 a.a.) |
| Gene ID - Human | |
| Gene ID - Mouse | |
| Gene ID - Rat | |
| Formulation | 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Citations for Anti-p62 (SQSTM1) (Human) pAb – 138 Found |
| Waguri, Satoshi; Komatsu, Masaaki. Biochemical and morphological detection of inclusion bodies in autophagy-deficient mice. Methods In Enzymology. 453:181-96. PubMed - Comments: Used in: WB |
| Waguri, Satoshi; Komatsu, Masaaki. Biochemical and morphological detection of inclusion bodies in autophagy-deficient mice. Methods In Enzymology. 453:181-96. PubMed - Comments: Used in: IHC |
| Otomo, Takanobu; Higaki, Katsumi; Nanba, Eiji; Ozono, Keiichi; Sakai, Norio. Inhibition of autophagosome formation restores mitochondrial function in mucolipidosis II and III skin fibroblasts. Molecular Genetics And Metabolism. 2009;98(4):393-9. PubMed - Comments: Used in: WB |
| Dupont, Nicolas; Lacas-Gervais, Sandra; Bertout, Julie; Paz, Irit; Freche, Barbara; Van Nhieu, Guy Tran; van der Goot, F Gisou; Sansonetti, Philippe J; Lafont, Frank. Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy. Cell Host & Microbe. 2009;6(2):137-49. PubMed - Comments: Used in: ICC |
| Ogata, Tomonori; Oishi, Yasuharu; Higuchi, Mitsuru; Muraoka, Isao. Fasting-related autophagic response in slow- and fast-twitch skeletal muscle. Biochemical And Biophysical Research Communications. 2010;394(1):136-40. PubMed - Comments: Used in: WB |
| Urbanczyk, Andreas; Jünemann, Anselm; Enz, Ralf. PKCζ-interacting protein ZIP3 is generated by intronic polyadenylation, and is expressed in the brain and retina of the rat. The Biochemical Journal. 2011;433(1):43-50. PubMed - Comments: Used in: IHC |
| Itakura, Eisuke; Mizushima, Noboru. p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. The Journal Of Cell Biology. 2011;192(1):17-27. PubMed - Comments: Used in: WB |
| Itakura, Eisuke; Mizushima, Noboru. p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. The Journal Of Cell Biology. 2011;192(1):17-27. PubMed - Comments: Used in: ICC |
| Lee, Eun-Ju; Tournier, Cathy. The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy. Autophagy. 2011;7(7):689-95. PubMed - Comments: Used in: WB |
| Higaki, Katsumi; Li, Linjing; Bahrudin, Udin; Okuzawa, Soichiro; Takamuram, Ayumi; Yamamoto, Koichi; Adachi, Kaori; Paraguison, Rubigilda C; Takai, Tomoko; Ikehata, Hiroki; Tominaga, Lika; Hisatome, Ichiro; Iida, Masami; Ogawa, Seiichiro; Matsuda, Junichiro; Ninomiya, Haruaki; Sakakibara, Yasubumi; Ohno, Kousaku; Suzuki, Yoshiyuki; Nanba, Eiji. Chemical chaperone therapy: chaperone effect on mutant enzyme and cellular pathophysiology in β-galactosidase deficiency. Human Mutation. 2011;32(7):843-52. PubMed - Comments: Used in: WB |
| Higaki, Katsumi; Li, Linjing; Bahrudin, Udin; Okuzawa, Soichiro; Takamuram, Ayumi; Yamamoto, Koichi; Adachi, Kaori; Paraguison, Rubigilda C; Takai, Tomoko; Ikehata, Hiroki; Tominaga, Lika; Hisatome, Ichiro; Iida, Masami; Ogawa, Seiichiro; Matsuda, Junichiro; Ninomiya, Haruaki; Sakakibara, Yasubumi; Ohno, Kousaku; Suzuki, Yoshiyuki; Nanba, Eiji. Chemical chaperone therapy: chaperone effect on mutant enzyme and cellular pathophysiology in β-galactosidase deficiency. Human Mutation. 2011;32(7):843-52. PubMed - Comments: Used in: ICC |
| Myeku, Natura; Figueiredo-Pereira, Maria E. Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. The Journal Of Biological Chemistry. 2011;286(25):22426-40. PubMed - Comments: Used in: WB |
| Myeku, Natura; Figueiredo-Pereira, Maria E. Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. The Journal Of Biological Chemistry. 2011;286(25):22426-40. PubMed - Comments: Used in: ICC |
| Takamura, Ayumi; Higaki, Katsumi; Ninomiya, Haruaki; Takai, Tomoko; Matsuda, Junichiro; Iida, Masami; Ohno, Kousaku; Suzuki, Yoshiyuki; Nanba, Eiji. Lysosomal accumulation of Trk protein in brain of GMâ -gangliosidosis mouse and its restoration by chemical chaperone. Journal Of Neurochemistry. 2011;118(3):399-406. PubMed - Comments: Used in: WB |
| Huang, Ying; Hou, Jia-Kai; Chen, Ting-Ting; Zhao, Xu-Yun; Yan, Zhao-Wen; Zhang, Jing; Yang, Jie; Kogan, Scott C; Chen, Guo-Qiang. PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway. Autophagy. 2011;7(10):1132-44. PubMed - Comments: Used in: WB |
| Huang, Chengqun; Andres, Allen M; Ratliff, Eric P; Hernandez, Genaro; Lee, Pamela; Gottlieb, Roberta A. Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1. Plos One. 6(6):e20975. PubMed - Comments: Used in: ICC |
| Osawa, Yosuke; Kanamori, Hiromitsu; Seki, Ekihiro; Hoshi, Masato; Ohtaki, Hirofumi; Yasuda, Yoichi; Ito, Hiroyasu; Suetsugu, Atsushi; Nagaki, Masahito; Moriwaki, Hisataka; Saito, Kuniaki; Seishima, Mitsuru. L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin. The Journal Of Biological Chemistry. 2011;286(40):34800-8. PubMed - Comments: Used in: WB |
| Frankel, Lisa B; Wen, Jiayu; Lees, Michael; Høyer-Hansen, Maria; Farkas, Thomas; Krogh, Anders; Jäättelä, Marja; Lund, Anders H. microRNA-101 is a potent inhibitor of autophagy. The Embo Journal. 2011;30(22):4628-41. PubMed - Comments: Used in: WB |
| Takaesu, Giichi; Kobayashi, Takashi; Yoshimura, Akihiko. TGFβ-activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy. Journal Of Biochemistry. 2012;151(2):157-66. PubMed - Comments: Used in: WB |
| Matsumoto, Gen; Wada, Koji; Okuno, Misako; Kurosawa, Masaru; Nukina, Nobuyuki. Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins. Molecular Cell. 2011;44(2):279-89. PubMed - Comments: Used in: WB |
| Berliocchi, Laura; Russo, Rossella; Maiarù, Maria; Levato, Alessandra; Bagetta, Giacinto; Corasaniti, Maria Tiziana. Autophagy impairment in a mouse model of neuropathic pain. Molecular Pain. 2011;7:83. PubMed - Comments: Used in: WB |
| Rovetta, Francesca; Stacchiotti, Alessandra; Consiglio, Antonella; Cadei, Moris; Grigolato, Pier Giovanni; Lavazza, Antonio; Rezzani, Rita; Aleo, Maria Francesca. ER signaling regulation drives the switch between autophagy and apoptosis in NRK-52E cells exposed to cisplatin. Experimental Cell Research. 2012;318(3):238-50. PubMed - Comments: Used in: WB |
| Wu, Shan-Ying; Lan, Sheng-Hui; Cheng, Da-En; Chen, Wei-Kai; Shen, Cheng-Huang; Lee, Ying-Ray; Zuchini, Roberto; Liu, Hsiao-Sheng. Ras-related tumorigenesis is suppressed by BNIP3-mediated autophagy through inhibition of cell proliferation. Neoplasia (New York, N.y.). 2011;13(12):1171-82. PubMed - Comments: Used in: WB |
| Seto, Shintaro; Tsujimura, Kunio; Koide, Yukio. Coronin-1a inhibits autophagosome formation around Mycobacterium tuberculosis-containing phagosomes and assists mycobacterial survival in macrophages. Cellular Microbiology. 2012;14(5):710-27. PubMed - Comments: Used in: ICC |
| Takasaka, Naoki; Araya, Jun; Hara, Hiromichi; Ito, Saburo; Kobayashi, Kenji; Kurita, Yusuke; Wakui, Hiroshi; Yoshii, Yutaka; Yumino, Yoko; Fujii, Satoko; Minagawa, Shunsuke; Tsurushige, Chikako; Kojima, Jun; Numata, Takanori; Shimizu, Kenichiro; Kawaishi, Makoto; Kaneko, Yumi; Kamiya, Noriki; Hirano, Jun; Odaka, Makoto; Morikawa, Toshiaki; Nishimura, Stephen L; Nakayama, Katsutoshi; Kuwano, Kazuyoshi. Autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in the regulation of human bronchial epithelial cell senescence. Journal Of Immunology (Baltimore, Md. : 1950). 2014;192(3):958-68. PubMed - Comments: Used in: WB |
| Chen, Hsiuchen; Ren, Shuxun; Clish, Clary; Jain, Mohit; Mootha, Vamsi; McCaffery, J Michael; Chan, David C. Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy. The Journal Of Cell Biology. 2015;211(4):795-805. PubMed - Comments: Used in: IHC |
| Sano, Osamu; Kazetani, Kenichi; Funata, Masaaki; Fukuda, Yasunori; Matsui, Junji; Iwata, Hidehisa. Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition. Febs Letters. 2016;590(11):1576-85. PubMed - Comments: Used in: ICC |
| Hasegawa, Junya; Iwamoto, Ryo; Otomo, Takanobu; Nezu, Akiko; Hamasaki, Maho; Yoshimori, Tamotsu. Autophagosome-lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome. The Embo Journal. 2016;35(17):1853-67. PubMed - Comments: Used in: WB |
| Cao, Qing-Hua; Liu, Fang; Yang, Zu-Li; Fu, Xin-Hui; Yang, Zi-Huan; Liu, Quentin; Wang, Lei; Wan, Xiang-Bo; Fan, Xin-Juan. Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer. American Journal Of Translational Research. 8(9):3831-3847. PubMed - Comments: Used in: WB |
| Cao, Qing-Hua; Liu, Fang; Yang, Zu-Li; Fu, Xin-Hui; Yang, Zi-Huan; Liu, Quentin; Wang, Lei; Wan, Xiang-Bo; Fan, Xin-Juan. Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer. American Journal Of Translational Research. 8(9):3831-3847. PubMed - Comments: Used in: IHC |
| Watanabe, Yuichiro; Honda, Shinya; Konishi, Akimitsu; Arakawa, Satoko; Murohashi, Michiko; Yamaguchi, Hirofumi; Torii, Satoru; Tanabe, Minoru; Tanaka, Shinji; Warabi, Eiji; Shimizu, Shigeomi. Autophagy controls centrosome number by degrading Cep63. Nature Communications. 2016;7:13508. PubMed - Comments: Used in: WB |
| Watanabe, Yuichiro; Honda, Shinya; Konishi, Akimitsu; Arakawa, Satoko; Murohashi, Michiko; Yamaguchi, Hirofumi; Torii, Satoru; Tanabe, Minoru; Tanaka, Shinji; Warabi, Eiji; Shimizu, Shigeomi. Autophagy controls centrosome number by degrading Cep63. Nature Communications. 2016;7:13508. PubMed - Comments: Used in: IP |
| Wakatsuki, Shuji; Tokunaga, Shinji; Shibata, Megumi; Araki, Toshiyuki. GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration. The Journal Of Cell Biology. 2017;216(2):477-493. PubMed - Comments: Used in: WB |
| Maueröder, Christian; Schall, Nicolas; Meyer, Frédéric; Mahajan, Aparna; Garnier, Benjamin; Hahn, Jonas; Kienhöfer, Deborah; Hoffmann, Markus H; Muller, Sylviane. Capability of Neutrophils to Form NETs Is Not Directly Influenced by a CMA-Targeting Peptide. Frontiers In Immunology. 8:16. PubMed - Comments: Used in: WB |
| Takayama, Kaori; Matsuura, Akira; Itakura, Eisuke. Dissection of ubiquitinated protein degradation by basal autophagy. Febs Letters. 2017;591(9):1199-1211. PubMed - Comments: Used in: WB |
| Takayama, Kaori; Matsuura, Akira; Itakura, Eisuke. Dissection of ubiquitinated protein degradation by basal autophagy. Febs Letters. 2017;591(9):1199-1211. PubMed - Comments: Used in: ICC |
| Zhao, Zhiwei; Li, Xiaoling; Li, Qing. Curcumin accelerates the repair of sciatic nerve injury in rats through reducing Schwann cells apoptosis and promoting myelinization. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 2017;92:1103-1110. PubMed - Comments: Used in: WB |
| Lee, Jaeyong; Homma, Takujiro; Fujii, Junichi. Mice in the early stage of liver steatosis caused by a high fat diet are resistant to thioacetamide-induced hepatotoxicity and oxidative stress. Toxicology Letters. 2017;277:92-103. PubMed - Comments: Used in: WB |
| Kobayashi, Sho; Lee, Jaeyong; Takao, Toshifumi; Fujii, Junichi. Increased ophthalmic acid production is supported by amino acid catabolism under fasting conditions in mice. Biochemical And Biophysical Research Communications. 2017;491(3):649-655. PubMed - Comments: Used in: WB |
| Liu, Wei Jing; Li, Zhi-Hang; Chen, Xiao-Cui; Zhao, Xiao-Lu; Zhong, Zhen; Yang, Chen; Wu, Hong-Luan; An, Ning; Li, Wei-Yan; Liu, Hua-Feng. Blockage of the lysosome-dependent autophagic pathway contributes to complement membrane attack complex-induced podocyte injury in idiopathic membranous nephropathy. Scientific Reports. 2017;7(1):8643. PubMed - Comments: Used in: IHC |
| Zhao, Qiong; Hu, Zhan-Ying; Zhang, Jing-Pu; Jiang, Jian-Dong; Ma, Yuan-Yuan; Li, Jian-Rui; Peng, Zong-Gen; Chen, Jin-Hua. Dual Roles of Two Isoforms of Autophagy-related Gene ATG10 in HCV-Subgenomic replicon Mediated Autophagy Flux and Innate Immunity. Scientific Reports. 2017;7(1):11250. PubMed - Comments: Used in: WB |
| Zhao, Qiong; Hu, Zhan-Ying; Zhang, Jing-Pu; Jiang, Jian-Dong; Ma, Yuan-Yuan; Li, Jian-Rui; Peng, Zong-Gen; Chen, Jin-Hua. Dual Roles of Two Isoforms of Autophagy-related Gene ATG10 in HCV-Subgenomic replicon Mediated Autophagy Flux and Innate Immunity. Scientific Reports. 2017;7(1):11250. PubMed - Comments: Used in: IP |
| Meng, Xiang-Hui; Chen, Bo; Zhang, Jing-Pu. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. International Journal Of Biological Sciences. 13(8):985-995. PubMed - Comments: Used in: WB |
| Tsuiji, Hitomi; Inoue, Ikuyo; Takeuchi, Mari; Furuya, Asako; Yamakage, Yuko; Watanabe, Seiji; Koike, Masato; Hattori, Mitsuharu; Yamanaka, Koji. TDP-43 accelerates age-dependent degeneration of interneurons. Scientific Reports. 2017;7(1):14972. PubMed - Comments: Used in: IHC |
| Necchi, Vittorio; Sommi, Patrizia; Vanoli, Alessandro; Fiocca, Roberto; Ricci, Vittorio; Solcia, Enrico. Natural history of Helicobacter pylori VacA toxin in human gastric epithelium in vivo: vacuoles and beyond. Scientific Reports. 2017;7(1):14526. PubMed |
| Tamura, Norito; Nishimura, Taki; Sakamaki, Yuriko; Koyama-Honda, Ikuko; Yamamoto, Hayashi; Mizushima, Noboru. Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets. Febs Letters. 2017;591(23):3819-3830. PubMed - Comments: Used in: WB |
| Sato, Yusuke; Ohtsubo, Hideaki; Nihei, Naohiro; Kaneko, Takane; Sato, Yoriko; Adachi, Shin-Ichi; Kondo, Shinji; Nakamura, Mako; Mizunoya, Wataru; Iida, Hiroshi; Tatsumi, Ryuichi; Rada, Cristina; Yoshizawa, Fumiaki. Apobec2 deficiency causes mitochondrial defects and mitophagy in skeletal muscle. Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology. 2018;32(3):1428-1439. PubMed - Comments: Used in: WB |
| Mizunoe, Yuhei; Kobayashi, Masaki; Sudo, Yuka; Watanabe, Shukoh; Yasukawa, Hiromine; Natori, Daiki; Hoshino, Ayana; Negishi, Arisa; Okita, Naoyuki; Komatsu, Masaaki; Higami, Yoshikazu. Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways. Redox Biology. 2018;15:115-124. PubMed - Comments: Used in: WB |
| Swinnen, Bart; Bento-Abreu, Andre; Gendron, Tania F; Boeynaems, Steven; Bogaert, Elke; Nuyts, Rik; Timmers, Mieke; Scheveneels, Wendy; Hersmus, Nicole; Wang, Jiou; Mizielinska, Sarah; Isaacs, Adrian M; Petrucelli, Leonard; Lemmens, Robin; Van Damme, Philip; Van Den Bosch, Ludo; Robberecht, Wim. A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism. Acta Neuropathologica. 2018;135(3):427-443. PubMed - Comments: Used in: WB |
| Festa, Beatrice Paola; Chen, Zhiyong; Berquez, Marine; Debaix, Huguette; Tokonami, Natsuko; Prange, Jenny Ann; Hoek, Glenn van de; Alessio, Cremonesi; Raimondi, Andrea; Nevo, Nathalie; Giles, Rachel H; Devuyst, Olivier; Luciani, Alessandro. Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney. Nature Communications. 2018;9(1):161. PubMed - Comments: Used in: WB |
| Gatta, Lucia; Vitiello, Laura; Gorini, Stefania; Chiandotto, Sergio; Costelli, Paola; Giammarioli, Anna Maria; Malorni, Walter; Rosano, Giuseppe; Ferraro, Elisabetta. Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice. Oncotarget. 2017;8(69):113938-113956. PubMed - Comments: Used in: WB |
| Ebner, Petra; Poetsch, Isabella; Deszcz, Luiza; Hoffmann, Thomas; Zuber, Johannes; Ikeda, Fumiyo. The IAP family member BRUCE regulates autophagosome-lysosome fusion. Nature Communications. 2018;9(1):599. PubMed - Comments: Used in: WB |
| Yamaguchi, Tomokazu; Suzuki, Takashi; Sato, Teruki; Takahashi, Akinori; Watanabe, Hiroyuki; Kadowaki, Ayumi; Natsui, Miyuki; Inagaki, Hideaki; Arakawa, Satoko; Nakaoka, Shinji; Koizumi, Yukio; Seki, Shinsuke; Adachi, Shungo; Fukao, Akira; Fujiwara, Toshinobu; Natsume, Tohru; Kimura, Akinori; Komatsu, Masaaki; Shimizu, Shigeomi; Ito, Hiroshi; Suzuki, Yutaka; Penninger, Josef M; Yamamoto, Tadashi; Imai, Yumiko; Kuba, Keiji. The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function. Science Signaling. 2018;11(516) PubMed - Comments: Used in: WB |
| Yamaguchi, Tomokazu; Suzuki, Takashi; Sato, Teruki; Takahashi, Akinori; Watanabe, Hiroyuki; Kadowaki, Ayumi; Natsui, Miyuki; Inagaki, Hideaki; Arakawa, Satoko; Nakaoka, Shinji; Koizumi, Yukio; Seki, Shinsuke; Adachi, Shungo; Fukao, Akira; Fujiwara, Toshinobu; Natsume, Tohru; Kimura, Akinori; Komatsu, Masaaki; Shimizu, Shigeomi; Ito, Hiroshi; Suzuki, Yutaka; Penninger, Josef M; Yamamoto, Tadashi; Imai, Yumiko; Kuba, Keiji. The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function. Science Signaling. 2018;11(516) PubMed - Comments: Used in: ICC |
| Piacentini, Mauro; Baiocchini, Andrea; Del Nonno, Franca; Melino, Gerry; Barlev, Nickolai A; Rossin, Federica; D'Eletto, Manuela; Falasca, Laura. Non-alcoholic fatty liver disease severity is modulated by transglutaminase type 2. Cell Death & Disease. 2018;9(3):257. PubMed - Comments: Used in: WB |
| Sukseree, Supawadee; László, Lajos; Gruber, Florian; Bergmann, Sophie; Narzt, Marie Sophie; Nagelreiter, Ionela Mariana; Höftberger, Romana; Molnár, Kinga; Rauter, Günther; Birngruber, Thomas; Larue, Lionel; Kovacs, Gabor G; Tschachler, Erwin; Eckhart, Leopold. Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7. Molecular Neurobiology. 2018;55(11):8425-8437. PubMed - Comments: Used in: IHC |
| Sukseree, Supawadee; László, Lajos; Gruber, Florian; Bergmann, Sophie; Narzt, Marie Sophie; Nagelreiter, Ionela Mariana; Höftberger, Romana; Molnár, Kinga; Rauter, Günther; Birngruber, Thomas; Larue, Lionel; Kovacs, Gabor G; Tschachler, Erwin; Eckhart, Leopold. Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7. Molecular Neurobiology. 2018;55(11):8425-8437. PubMed |
| Uemura, Norihito; Yagi, Hisashi; Uemura, Maiko T; Hatanaka, Yusuke; Yamakado, Hodaka; Takahashi, Ryosuke. Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Molecular Neurodegeneration. 2018;13(1):21. PubMed - Comments: Used in: IHC |
| Ito, Tomohisa; Ando, Takashi; Suzuki-Karasaki, Miki; Tokunaga, Tomohiko; Yoshida, Yukihiro; Ochiai, Toyoko; Tokuhashi, Yasuaki; Suzuki-Karasaki, Yoshihiro. Cold PSM, but not TRAIL, triggers autophagic cell death: A therapeutic advantage of PSM over TRAIL. International Journal Of Oncology. 2018;53(2):503-514. PubMed - Comments: Used in: WB |
| Zhan, Rui; Zhao, Mingming; Zhou, Ting; Chen, Yue; Yu, Weiwei; Zhao, Lei; Zhang, Tao; Wang, Hecheng; Yang, Huan; Jin, Yinglan; He, Qihua; Yang, Xiaoda; Guo, Xiangyang; Willard, Belinda; Pan, Bing; Huang, Yining; Chen, Yingyu; Chui, Dehua; Zheng, Lemin. Dapsone protects brain microvascular integrity from high-fat diet induced LDL oxidation. Cell Death & Disease. 2018;9(6):683. PubMed - Comments: Used in: WB |
| Zhan, Rui; Zhao, Mingming; Zhou, Ting; Chen, Yue; Yu, Weiwei; Zhao, Lei; Zhang, Tao; Wang, Hecheng; Yang, Huan; Jin, Yinglan; He, Qihua; Yang, Xiaoda; Guo, Xiangyang; Willard, Belinda; Pan, Bing; Huang, Yining; Chen, Yingyu; Chui, Dehua; Zheng, Lemin. Dapsone protects brain microvascular integrity from high-fat diet induced LDL oxidation. Cell Death & Disease. 2018;9(6):683. PubMed - Comments: Used in: FCM |
| Adams, Olivia; Janser, Félice A; Dislich, Bastian; Berezowska, Sabina; Humbert, Magali; Seiler, Christian A; Kroell, Dino; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Tschan, Mario P; Langer, Rupert. A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. Plos One. 13(6):e0197610. PubMed - Comments: Used in: IHC |
| Matsumoto, Gen; Inobe, Tomonao; Amano, Takanori; Murai, Kiyohito; Nukina, Nobuyuki; Mori, Nozomu. N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression. Scientific Reports. 2018;8(1):9585. PubMed - Comments: Used in: WB |
| Lin, Xin; Cui, Ming; Xu, Dong; Hong, Dubeiqi; Xia, Yan; Xu, Chentong; Li, Riyong; Zhang, Xuan; Lou, Yaxin; He, Qihua; Lv, Ping; Chen, Yingyu. Liver-specific deletion of Eva1a/Tmem166 aggravates acute liver injury by impairing autophagy. Cell Death & Disease. 2018;9(7):768. PubMed - Comments: Used in: WB |
| Chen, Bo; Zheng, Yang-Min; Zhang, Jing-Pu. Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish. Frontiers In Endocrinology. 9:366. PubMed - Comments: Used in: WB |
| Bak, Dong-Ho; Na, Jungtae; Choi, Mi Ji; Lee, Byung Chul; Oh, Chang Taek; Kim, Jeom-Yong; Han, Hae Jung; Kim, Moo Joong; Kim, Tae Ho; Kim, Beom Joon. Antiâapoptotic effects of human placental hydrolysate against hepatocyte toxicity in vivo and in vitro. International Journal Of Molecular Medicine. 2018;42(5):2569-2583. PubMed - Comments: Used in: WB |
| Sil, Susmita; Niu, Fang; Tom, Eric; Liao, Ke; Periyasamy, Palsamy; Buch, Shilpa. Cocaine Mediated Neuroinflammation: Role of Dysregulated Autophagy in Pericytes. Molecular Neurobiology. 2019;56(5):3576-3590. PubMed - Comments: Used in: WB |
| Liu, Xiaofeng; Cai, Shiying; Zhang, Chunfeng; Liu, Zhenzhen; Luo, Jianyuan; Xing, Baocai; Du, Xiaojuan. Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress. Nucleic Acids Research. 2018;46(18):9601-9616. PubMed - Comments: Used in: WB |
| Götzl, Julia K; Colombo, Alessio-Vittorio; Fellerer, Katrin; Reifschneider, Anika; Werner, Georg; Tahirovic, Sabina; Haass, Christian; Capell, Anja. Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice. Molecular Neurodegeneration. 2018;13(1):48. PubMed - Comments: Used in: WB |
| Jin, Gui-Lin; Yue, Rong-Cai; He, Sai-di; Hong, Li-Mian; Xu, Ying; Yu, Chang-Xi. Koumine Decreases Astrocyte-Mediated Neuroinflammation and Enhances Autophagy, Contributing to Neuropathic Pain From Chronic Constriction Injury in Rats. Frontiers In Pharmacology. 9:989. PubMed - Comments: Used in: WB |
| Osaki, Yosuke; Saito, Atsushi; Kanemoto, Soshi; Kaneko, Masayuki; Matsuhisa, Koji; Asada, Rie; Masaki, Takao; Orii, Kenji; Fukao, Toshiyuki; Tomatsu, Shunji; Imaizumi, Kazunori. Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II. Cell Death & Disease. 2018;9(8):808. PubMed - Comments: Used in: WB |
| Qiu, Jingping; Li, Xiaoting; He, Yingjian; Sun, Dan; Li, Wenhui; Xin, Yan. Distinct subgroup of the Ras family member 3 (DIRAS3) expression impairs metastasis and induces autophagy of gastric cancer cells in mice. Journal Of Cancer Research And Clinical Oncology. 2018;144(10):1869-1886. PubMed - Comments: Used in: IHC |
| Sun, Yameng; Zhang, Ting; Zhang, Yan; Li, Jinfeng; Jin, Lei; Sun, Yinyi; Shi, Nan; Liu, Kangyong; Sun, Xiaojiang. Ischemic Postconditioning Alleviates Cerebral Ischemia-Reperfusion Injury Through Activating Autophagy During Early Reperfusion in Rats. Neurochemical Research. 2018;43(9):1826-1840. PubMed - Comments: Used in: WB |
| Gkirtzimanaki, Katerina; Kabrani, Eleni; Nikoleri, Dimitra; Polyzos, Alexander; Blanas, Athanasios; Sidiropoulos, Prodromos; Makrigiannakis, Antonis; Bertsias, George; Boumpas, Dimitrios T; Verginis, Panayotis. IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion. Cell Reports. 2018;25(4):921-933.e5. PubMed - Comments: Used in: WB |
| Gkirtzimanaki, Katerina; Kabrani, Eleni; Nikoleri, Dimitra; Polyzos, Alexander; Blanas, Athanasios; Sidiropoulos, Prodromos; Makrigiannakis, Antonis; Bertsias, George; Boumpas, Dimitrios T; Verginis, Panayotis. IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion. Cell Reports. 2018;25(4):921-933.e5. PubMed - Comments: Used in: ICC |
| Chou, Li-Fang; Cheng, Ya-Lien; Hsieh, Chun-Yih; Lin, Chan-Yu; Yang, Huang-Yu; Chen, Yung-Chang; Hung, Cheng-Chieh; Tian, Ya-Chung; Yang, Chih-Wei; Chang, Ming-Yang. Effect of Trehalose Supplementation on Autophagy and Cystogenesis in a Mouse Model of Polycystic Kidney Disease. Nutrients. 2018;11(1) PubMed - Comments: Used in: WB |
| Chou, Li-Fang; Cheng, Ya-Lien; Hsieh, Chun-Yih; Lin, Chan-Yu; Yang, Huang-Yu; Chen, Yung-Chang; Hung, Cheng-Chieh; Tian, Ya-Chung; Yang, Chih-Wei; Chang, Ming-Yang. Effect of Trehalose Supplementation on Autophagy and Cystogenesis in a Mouse Model of Polycystic Kidney Disease. Nutrients. 2018;11(1) PubMed - Comments: Used in: IHC |
| Benkafadar, Nesrine; François, Florence; Affortit, Corentin; Casas, François; Ceccato, Jean-Charles; Menardo, Julien; Venail, Frederic; Malfroy-Camine, Bernard; Puel, Jean-Luc; Wang, Jing. ROS-Induced Activation of DNA Damage Responses Drives Senescence-Like State in Postmitotic Cochlear Cells: Implication for Hearing Preservation. Molecular Neurobiology. 2019;56(8):5950-5969. PubMed - Comments: Used in: WB |
| Aki, Toshihiko; Unuma, Kana; Noritake, Kanako; Hirayama, Naho; Funakoshi, Takeshi; Uemura, Koichi. Formation of high molecular weight p62 by CORM-3. Plos One. 14(1):e0210474. PubMed - Comments: Used in: WB |
| Aki, Toshihiko; Unuma, Kana; Noritake, Kanako; Hirayama, Naho; Funakoshi, Takeshi; Uemura, Koichi. Formation of high molecular weight p62 by CORM-3. Plos One. 14(1):e0210474. PubMed - Comments: Used in: ICC |
| Lu, Shen-Zhao; Guo, Yong-Shun; Liang, Pei-Zhou; Zhang, Shu-Zhen; Yin, Shu; Yin, Yan-Qing; Wang, Xiao-Min; Ding, Fei; Gu, Xiao-Song; Zhou, Jia-Wei. Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation. Translational Neurodegeneration. 8:3. PubMed - Comments: Used in: WB |
| Lu, Shen-Zhao; Guo, Yong-Shun; Liang, Pei-Zhou; Zhang, Shu-Zhen; Yin, Shu; Yin, Yan-Qing; Wang, Xiao-Min; Ding, Fei; Gu, Xiao-Song; Zhou, Jia-Wei. Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation. Translational Neurodegeneration. 8:3. PubMed - Comments: Used in: IHC |
| Hoffmann, Anna-Carin; Minakaki, Georgia; Menges, Stefanie; Salvi, Rachele; Savitskiy, Sergey; Kazman, Aida; Vicente Miranda, Hugo; Mielenz, Dirk; Klucken, Jochen; Winkler, Jürgen; Xiang, Wei. Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose. Scientific Reports. 2019;9(1):544. PubMed - Comments: Used in: WB |
| Ohashi, Tomohiko; Nakade, Yukiomi; Ibusuki, Mayu; Kitano, Rena; Yamauchi, Taeko; Kimoto, Satoshi; Inoue, Tadahisa; Kobayashi, Yuji; Sumida, Yoshio; Ito, Kiyoaki; Nakao, Haruhisa; Umezawa, Kazuo; Yoneda, Masashi. Conophylline inhibits high fat diet-induced non-alcoholic fatty liver disease in mice. Plos One. 14(1):e0210068. PubMed - Comments: Used in: WB |
| Ohashi, Tomohiko; Nakade, Yukiomi; Ibusuki, Mayu; Kitano, Rena; Yamauchi, Taeko; Kimoto, Satoshi; Inoue, Tadahisa; Kobayashi, Yuji; Sumida, Yoshio; Ito, Kiyoaki; Nakao, Haruhisa; Umezawa, Kazuo; Yoneda, Masashi. Conophylline inhibits high fat diet-induced non-alcoholic fatty liver disease in mice. Plos One. 14(1):e0210068. PubMed - Comments: Used in: IHC |
| Scrivo, Aurora; Codogno, Patrice; Bomont, Pascale. Gigaxonin E3 ligase governs ATG16L1 turnover to control autophagosome production. Nature Communications. 2019;10(1):780. PubMed - Comments: Used in: WB |
| Nakamura, Shuhei; Oba, Masaki; Suzuki, Mari; Takahashi, Atsushi; Yamamuro, Tadashi; Fujiwara, Mari; Ikenaka, Kensuke; Minami, Satoshi; Tabata, Namine; Yamamoto, Kenichi; Kubo, Sayaka; Tokumura, Ayaka; Akamatsu, Kanako; Miyazaki, Yumi; Kawabata, Tsuyoshi; Hamasaki, Maho; Fukui, Koji; Sango, Kazunori; Watanabe, Yoshihisa; Takabatake, Yoshitsugu; Kitajima, Tomoya S; Okada, Yukinori; Mochizuki, Hideki; Isaka, Yoshitaka; Antebi, Adam; Yoshimori, Tamotsu. Suppression of autophagic activity by Rubicon is a signature of aging. Nature Communications. 2019;10(1):847. PubMed - Comments: Used in: WB |
| Hsu, Yung-Ho; Chuang, Hsiao-Chi; Lee, Yu-Hsuan; Lin, Yuh-Feng; Chen, Yi-Jie; Hsiao, Ta-Chih; Wu, Mei-Yi; Chiu, Hui-Wen. Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo. Free Radical Biology & Medicine. 2019;135:235-244. PubMed - Comments: Used in: WB |
| Nakajima, Shinsuke; Nishimoto, Yuki; Tateya, Sanshiro; Iwahashi, Yasuyuki; Okamatsu-Ogura, Yuko; Saito, Masayuki; Ogawa, Wataru; Tamori, Yoshikazu. Fat-specific protein 27α inhibits autophagy-dependent lipid droplet breakdown in white adipocytes. Journal Of Diabetes Investigation. 2019;10(6):1419-1429. PubMed - Comments: Used in: WB |
| Ding, Xianming; Jiang, Xiao; Tian, Rui; Zhao, Pengwei; Li, Lin; Wang, Xinyi; Chen, She; Zhu, Yushan; Mei, Mei; Bao, Shilai; Liu, Wei; Tang, Zaiming; Sun, Qiming. RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells. Autophagy. 2019;15(10):1774-1786. PubMed - Comments: Used in: ICC |
| Slowicka, Karolina; Serramito-Gómez, Inmaculada; Boada-Romero, Emilio; Martens, Arne; Sze, Mozes; Petta, Ioanna; Vikkula, Hanna K; De Rycke, Riet; Parthoens, Eef; Lippens, Saskia; Savvides, Savvas N; Wullaert, Andy; Vereecke, Lars; Pimentel-Muiños, Felipe X; van Loo, Geert. Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis. Nature Communications. 2019;10(1):1834. PubMed - Comments: Used in: WB |
| Wang, Yan; Zhao, Hailing; Li, Xin; Li, Nan; Wang, Qian; Liu, Yanzhen; Liang, Qionglin; Shao, Zixing; Zhang, Nannan; Zhao, Tingting; Peng, Liang; Li, Ping. Tangshen Formula Alleviates Hepatic Steatosis by Inducing Autophagy Through the AMPK/SIRT1 Pathway. Frontiers In Physiology. 10:494. PubMed - Comments: Used in: WB |
| Zhu, Liyuan; Zhu, Yiran; Han, Shuting; Chen, Miaoqin; Song, Ping; Dai, Dongjun; Xu, Wenxia; Jiang, Tingting; Feng, Lifeng; Shin, Vivian Y; Wang, Xian; Jin, Hongchuan. Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer. Cell Death & Disease. 2019;10(6):383. PubMed - Comments: Used in: WB |
| Homma, Takujiro; Fujii, Junichi. An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage in mice. Biochimica Et Biophysica Acta. General Subjects. 2019;1863(6):1108-1115. PubMed - Comments: Used in: WB |
| Homma, Takujiro; Fujii, Junichi. An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage in mice. Biochimica Et Biophysica Acta. General Subjects. 2019;1863(6):1108-1115. PubMed - Comments: Used in: IHC |
| Liu, Na; Luo, Jing; Kuang, Dong; Xu, Sanpeng; Duan, Yaqi; Xia, Yu; Wei, Zhengping; Xie, Xiuxiu; Yin, Bingjiao; Chen, Fang; Luo, Shunqun; Liu, Huicheng; Wang, Jing; Jiang, Kan; Gong, Feili; Tang, Zhao-Hui; Cheng, Xiang; Li, Huabin; Li, Zhuoya; Laurence, Arian; Wang, Guoping; Yang, Xiang-Ping. Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression. The Journal Of Clinical Investigation. 2019;129(2):631-646. PubMed - Comments: Used in: WB |
| Wei, Ran; Enaka, Mayu; Muragaki, Yasuteru. Activation of KEAP1/NRF2/P62 signaling alleviates high phosphate-induced calcification of vascular smooth muscle cells by suppressing reactive oxygen species production. Scientific Reports. 2019;9(1):10366. PubMed - Comments: Used in: WB |
| Puri, Rajat; Cheng, Xiu-Tang; Lin, Mei-Yao; Huang, Ning; Sheng, Zu-Hang. Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts. Nature Communications. 2019;10(1):3645. PubMed - Comments: Used in: ICC |
| Yang, Yi; Willis, Thea L; Button, Robert W; Strang, Conor J; Fu, Yuhua; Wen, Xue; Grayson, Portia R C; Evans, Tracey; Sipthorpe, Rebecca J; Roberts, Sheridan L; Hu, Bing; Zhang, Jianke; Lu, Boxun; Luo, Shouqing. Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response. Nature Communications. 2019;10(1):3759. PubMed - Comments: Used in: WB |
| Kanazawa, Takumi. Effect of Ovariectomy and Ovarian Hormone Administration on Hepatic Autophagy in Female Rats. Journal Of Nutritional Science And Vitaminology. 65(4):357-361. PubMed - Comments: Used in: WB |
| Tripathi, Ashutosh; Thangaraj, Annadurai; Chivero, Ernest T; Periyasamy, Palsamy; Callen, Shannon; Burkovetskaya, Maria E; Guo, Ming-Lei; Buch, Shilpa. Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction. Cells. 2019;8(10) PubMed - Comments: Used in: WB |
| Holdgaard, Søs Grønbæk; Cianfanelli, Valentina; Pupo, Emanuela; Lambrughi, Matteo; Lubas, Michal; Nielsen, Julie C; Eibes, Susana; Maiani, Emiliano; Harder, Lea M; Wesch, Nicole; Foged, Mads Møller; Maeda, Kenji; Nazio, Francesca; de la Ballina, Laura R; Dötsch, Volker; Brech, Andreas; Frankel, Lisa B; Jäättelä, Marja; Locatelli, Franco; Barisic, Marin; Andersen, Jens S; Bekker-Jensen, Simon; Lund, Anders H; Rogov, Vladimir V; Papaleo, Elena; Lanzetti, Letizia; De Zio, Daniela; Cecconi, Francesco. Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. Nature Communications. 2019;10(1):4176. PubMed - Comments: Used in: WB |
| Morishita, Hideaki; Zhao, Yan G; Tamura, Norito; Nishimura, Taki; Kanda, Yuki; Sakamaki, Yuriko; Okazaki, Mitsuyo; Li, Dongfang; Mizushima, Noboru. A critical role of VMP1 in lipoprotein secretion. Elife. 2019;8 PubMed - Comments: Used in: IHC |
| Makanae, Yuhei; Ato, Satoru; Kido, Kohei; Fujita, Satoshi. Dietary Aronia melanocarpa extract enhances mTORC1 signaling, but has no effect on protein synthesis and protein breakdown-related signaling, in response to resistance exercise in rat skeletal muscle. Journal Of The International Society Of Sports Nutrition. 2019;16(1):60. PubMed - Comments: Used in: WB |
| Goulielmaki, Evi; Ioannidou, Anna; Tsekrekou, Maria; Stratigi, Kalliopi; Poutakidou, Ioanna K; Gkirtzimanaki, Katerina; Aivaliotis, Michalis; Evangelou, Konstantinos; Topalis, Pantelis; Altmüller, Janine; Gorgoulis, Vassilis G; Chatzinikolaou, Georgia; Garinis, George A. Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage. Nature Communications. 2020;11(1):42. PubMed - Comments: Used in: WB |
| Goulielmaki, Evi; Ioannidou, Anna; Tsekrekou, Maria; Stratigi, Kalliopi; Poutakidou, Ioanna K; Gkirtzimanaki, Katerina; Aivaliotis, Michalis; Evangelou, Konstantinos; Topalis, Pantelis; Altmüller, Janine; Gorgoulis, Vassilis G; Chatzinikolaou, Georgia; Garinis, George A. Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage. Nature Communications. 2020;11(1):42. PubMed - Comments: Used in: IF |
| Omi, Jumpei; Watanabe-Takahashi, Miho; Igai, Katsura; Shimizu, Eiko; Tseng, Ching-Yi; Miyasaka, Tomohiro; Waku, Tsuyoshi; Hama, Shinichiro; Nakanishi, Rieka; Goto, Yuki; Nishino, Yuri; Miyazawa, Atsuo; Natori, Yasuhiro; Yamashita, Makoto; Nishikawa, Kiyotaka. The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection. Nature Communications. 2020;11(1):162. PubMed - Comments: Used in: ICC |
| Kobayashi, Shintaro; Yoshii, Kentaro; Phongphaew, Wallaya; Muto, Memi; Hirano, Minato; Orba, Yasuko; Sawa, Hirofumi; Kariwa, Hiroaki. West Nile virus capsid protein inhibits autophagy by AMP-activated protein kinase degradation in neurological disease development. Plos Pathogens. 2020;16(1):e1008238. PubMed - Comments: Used in: WB |
| Jakobi, Arjen J; Huber, Stefan T; Mortensen, Simon A; Schultz, Sebastian W; Palara, Anthimi; Kuhm, Tanja; Shrestha, Birendra Kumar; Lamark, Trond; Hagen, Wim J H; Wilmanns, Matthias; Johansen, Terje; Brech, Andreas; Sachse, Carsten. Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake. Nature Communications. 2020;11(1):440. PubMed |
| Liu, Beibei; Deng, Xiaoling; Jiang, Qianqian; Li, Guixin; Zhang, Junli; Zhang, Ning; Xin, Shengliang; Xu, Keshu. Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 2020;125:109895. PubMed - Comments: Used in: WB |
| Yoshikawa, Nobuhisa; Liu, Wenting; Nakamura, Kae; Yoshida, Kosuke; Ikeda, Yoshiki; Tanaka, Hiromasa; Mizuno, Masaaki; Toyokuni, Shinya; Hori, Masaru; Kikkawa, Fumitaka; Kajiyama, Hiroaki. Plasma-activated medium promotes autophagic cell death along with alteration of the mTOR pathway. Scientific Reports. 2020;10(1):1614. PubMed - Comments: Used in: WB |
| Luciani, Alessandro; Schumann, Anke; Berquez, Marine; Chen, Zhiyong; Nieri, Daniela; Failli, Mario; Debaix, Huguette; Festa, Beatrice Paola; Tokonami, Natsuko; Raimondi, Andrea; Cremonesi, Alessio; Carrella, Diego; Forny, Patrick; Kölker, Stefan; Diomedi Camassei, Francesca; Diaz, Francisca; Moraes, Carlos T; Di Bernardo, Diego; Baumgartner, Matthias R; Devuyst, Olivier. Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nature Communications. 2020;11(1):970. PubMed - Comments: Used in: WB |
| Luciani, Alessandro; Schumann, Anke; Berquez, Marine; Chen, Zhiyong; Nieri, Daniela; Failli, Mario; Debaix, Huguette; Festa, Beatrice Paola; Tokonami, Natsuko; Raimondi, Andrea; Cremonesi, Alessio; Carrella, Diego; Forny, Patrick; Kölker, Stefan; Diomedi Camassei, Francesca; Diaz, Francisca; Moraes, Carlos T; Di Bernardo, Diego; Baumgartner, Matthias R; Devuyst, Olivier. Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nature Communications. 2020;11(1):970. PubMed - Comments: Used in: IF |
| Kobayashi, Mutsumi; Yoshino, Osamu; Nakashima, Akitoshi; Ito, Masami; Nishio, Kazuyuki; Ono, Yosuke; Kusabiraki, Tae; Kunitomi, Chisato; Takahashi, Nozomi; Harada, Miyuki; Hattori, Katsushige; Orisaka, Makoto; Osuga, Yutaka; Saito, Shigeru. Inhibition of autophagy in theca cells induces CYP17A1 and PAI-1 expression via ROS/p38 and JNK signalling during the development of polycystic ovary syndrome. Molecular And Cellular Endocrinology. 2020;508:110792. PubMed - Comments: Used in: WB |
| Kobayashi, Mutsumi; Yoshino, Osamu; Nakashima, Akitoshi; Ito, Masami; Nishio, Kazuyuki; Ono, Yosuke; Kusabiraki, Tae; Kunitomi, Chisato; Takahashi, Nozomi; Harada, Miyuki; Hattori, Katsushige; Orisaka, Makoto; Osuga, Yutaka; Saito, Shigeru. Inhibition of autophagy in theca cells induces CYP17A1 and PAI-1 expression via ROS/p38 and JNK signalling during the development of polycystic ovary syndrome. Molecular And Cellular Endocrinology. 2020;508:110792. PubMed - Comments: Used in: IHC |
| Ma, Yuan-Yuan; Li, Jian-Rui; Peng, Zong-Gen; Zhang, Jing-Pu. IL28A protein homotetramer structure is required for autolysosomal degradation of HCV-NS5A in vitro. Cell Death & Disease. 2020;11(3):200. PubMed - Comments: Used in: WB |
| Ma, Yuan-Yuan; Li, Jian-Rui; Peng, Zong-Gen; Zhang, Jing-Pu. IL28A protein homotetramer structure is required for autolysosomal degradation of HCV-NS5A in vitro. Cell Death & Disease. 2020;11(3):200. PubMed - Comments: Used in: IF |
| Shizukuishi, Sayaka; Ogawa, Michinaga; Matsunaga, Satoko; Tomokiyo, Mikado; Ikebe, Tadayoshi; Fushinobu, Shinya; Ryo, Akihide; Ohnishi, Makoto. Streptococcus pneumoniae hijacks host autophagy by deploying CbpC as a decoy for Atg14 depletion. Embo Reports. 2020;21(5):e49232. PubMed - Comments: Used in: WB |
| Wang, Shu-Ya; Ni, Xi; Hu, Ke-Qing; Meng, Fan-Liang; Li, Min; Ma, Xiao-Li; Meng, Ting-Ting; Wu, Hui-Hui; Ge, Di; Zhao, Jing; Li, Ying; Su, Guo-Hai. Cilostazol alleviate nicotine induced cardiomyocytes hypertrophy through modulation of autophagy by CTSB/ROS/p38MAPK/JNK feedback loop. International Journal Of Biological Sciences. 16(11):2001-2013. PubMed - Comments: Used in: WB |
| Wang, Mingxiang; Li, Jin; Dong, Shunni; Cai, Xiaobo; Simaiti, Aili; Yang, Xin; Zhu, Xinqiang; Luo, Jianhong; Jiang, Lin-Hua; Du, Binyang; Yu, Peilin; Yang, Wei. Silica nanoparticles induce lung inflammation in mice via ROS/PARP/TRPM2 signaling-mediated lysosome impairment and autophagy dysfunction. Particle And Fibre Toxicology. 2020;17(1):23. PubMed - Comments: Used in: WB |
| Zhang, Xuequn; Lin, Yiming; Lin, Sisi; Li, Chunxiao; Gao, Jianguo; Feng, Zemin; Wang, Jinghua; Zhang, Jie; Zhang, Hong; Zhang, Yuwei; Chen, Xueyang; Chen, Shenghui; Xu, Chengfu; Li, Youming; Yu, Chaohui; Zeng, Hang. Silencing of functional p53 attenuates NAFLD by promoting HMGB1-related autophagy induction. Hepatology International. 2020;14(5):828-841. PubMed - Comments: Used in: WB |
| Zhang, Xuequn; Lin, Yiming; Lin, Sisi; Li, Chunxiao; Gao, Jianguo; Feng, Zemin; Wang, Jinghua; Zhang, Jie; Zhang, Hong; Zhang, Yuwei; Chen, Xueyang; Chen, Shenghui; Xu, Chengfu; Li, Youming; Yu, Chaohui; Zeng, Hang. Silencing of functional p53 attenuates NAFLD by promoting HMGB1-related autophagy induction. Hepatology International. 2020;14(5):828-841. PubMed - Comments: Used in: WB |
| Noguchi, Mari; Kitakaze, Tomoya; Kobayashi, Yasuyuki; Mukai, Katsuyuki; Harada, Naoki; Yamaji, Ryoichi. β-Cryptoxanthin Improves p62 Accumulation and Muscle Atrophy in the Soleus Muscle of Senescence-Accelerated Mouse-Prone 1 Mice. Nutrients. 2020;12(8) PubMed - Comments: Used in: IF |
| Yang, Ying; Ying, Gaoxiang; Wu, Fengtian; Chen, Zhi. sTim-3 alleviates liver injury via regulation of the immunity microenvironment and autophagy. Cell Death Discovery. 6:62. PubMed - Comments: Used in: WB |
| Tokinoya, Katsuyuki; Shirai, Takanaga; Ota, Yuya; Takemasa, Tohru; Takekoshi, Kazuhiro. Denervation-induced muscle atrophy suppression in renalase-deficient mice via increased protein synthesis. Physiological Reports. 2020;8(15):e14475. PubMed - Comments: Used in: WB |
| Yamamuro, Tadashi; Kawabata, Tsuyoshi; Fukuhara, Atsunori; Saita, Shotaro; Nakamura, Shuhei; Takeshita, Hikari; Fujiwara, Mari; Enokidani, Yusuke; Yoshida, Gota; Tabata, Keisuke; Hamasaki, Maho; Kuma, Akiko; Yamamoto, Koichi; Shimomura, Iichiro; Yoshimori, Tamotsu. Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. Nature Communications. 2020;11(1):4150. PubMed - Comments: Used in: WB |
| Nishikawa, Sakiko; Inoue, Yasumichi; Hori, Yuka; Miyajima, Chiharu; Morishita, Daisuke; Ohoka, Nobumichi; Hida, Shigeaki; Makino, Toshiaki; Hayashi, Hidetoshi. Anti-Inflammatory Activity of Kurarinone Involves Induction of HO-1 via the KEAP1/Nrf2 Pathway. Antioxidants (Basel, Switzerland). 2020;9(9) PubMed - Comments: Used in: WB |
| Fujiwara, Nobuyuki; Shibutani, Shusaku; Sakai, Yusuke; Watanabe, Toshio; Kitabayashi, Issay; Oshima, Hiroko; Oshima, Masanobu; Hoshida, Hisashi; Akada, Rinji; Usui, Tatsuya; Ohama, Takashi; Sato, Koichi. Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 6. Cancer Science. 2020;111(12):4371-4380. PubMed - Comments: Used in: WB |
| Tripathi, Ashutosh; Thangaraj, Annadurai; Chivero, Ernest T; Periyasamy, Palsamy; Burkovetskaya, Maria E; Niu, Fang; Guo, Ming-Lei; Buch, Shilpa. N-Acetylcysteine Reverses Antiretroviral-Mediated Microglial Activation by Attenuating Autophagy-Lysosomal Dysfunction. Frontiers In Neurology. 11:840. PubMed - Comments: Used in: WB |
| Sun, Siyuan; He, Hengqian; Ma, Yuan |