Application: WB, ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: optineurin
Gene Name: OPTN
Alternative Gene Name: FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000026672: 64%, ENSRNOG00000017941: 68%
Entrez Gene ID: 10133
Uniprot ID: Q96CV9
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: optineurin
Gene Name: OPTN
Alternative Gene Name: FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000026672: 64%, ENSRNOG00000017941: 68%
Entrez Gene ID: 10133
Uniprot ID: Q96CV9
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti OPTN pAb (ATL-HPA003360 w/enhanced validation) | |
| Antigen | PrEST Antigen OPTN (ATL-APrEST85212) |
| Documents & Links for Anti OPTN pAb (ATL-HPA003360 w/enhanced validation) | |
| Datasheet | Anti OPTN pAb (ATL-HPA003360 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti OPTN pAb (ATL-HPA003360 w/enhanced validation) at Atlas |
| Documents & Links for Anti OPTN pAb (ATL-HPA003360 w/enhanced validation) | |
| Datasheet | Anti OPTN pAb (ATL-HPA003360 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti OPTN pAb (ATL-HPA003360 w/enhanced validation) |
| Citations for Anti OPTN pAb (ATL-HPA003360 w/enhanced validation) – 3 Found |
| Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria. Dev Cell. 2018 Feb 26;44(4):484-499.e6. doi: 10.1016/j.devcel.2018.01.007. Epub 2018 Feb 1. PubMed |
| Disruption of macrophage pro-inflammatory cytokine release in Crohn's disease is associated with reduced optineurin expression in a subset of patients. Immunology. 2015 Jan;144(1):45-55. doi: 10.1111/imm.12338. PubMed |
| OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion. J Cell Sci. 2020 Jun 15;133(12):jcs239822. doi: 10.1242/jcs.239822. PubMed |