Anti Nuclear Pore Complex Protein NUP153 (NUP153) mAb (Clone 7F9E12)

Cosmo Bio

Catalog No: CAC-CEC-031

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Product Description

Background
Nucleoporin 153 (Nup153) is a protein which in humans is encoded by the NUP153 gene. It is an essential component of the basket of nuclear pore complexes (NPCs) in vertebrates and required for the anchoring of NPCs. It also acts as the docking site of an importing karyopherin.[5] On the cytoplasmic side of the NPC, Nup358 fulfills an analogous role.

Nucleoporin 153 has a mass of 153 kDa (hence its name). It is filamentous and it contains three distinct domains: an N-terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats.[6] [from: Wikipedia contributors. (2019, June 3). Nucleoporin 153. In Wikipedia, The Free Encyclopedia. Retrieved 22:46, June 4, 2019, from https://en.wikipedia.org/w/index.php?title=Nucleoporin_153&oldid=900179284] 

Application
Western blotting, 1/1,000 to 1/5,000
Immunocytochemistry, 1/100 to 1/500

References
Ball and Ullman (2005) Chromosoma. 114:319-330.

Product Specifications

• Application: ICC, WB, IF
• Reactivity: Human
• Clonality: Monoclonal (Clone No.: 7F9E12)
• Host: Rat