Anti Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) pAb (Rabbit, Affinity Purified)

Cosmo Bio LTD

Catalog No: CAC-THU-A-NOD2

Catalog numbers beginning with "CAC" are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.

A cytosolic surveillance system mediated by the nucleotide-binding oligomerization domain (NOD) proteins plays an important role in recognizing intracellular microbe-associated molecular patterns (MAMPs). NOD2 recognizes low-molecularpeptidoglycan fragments, such as muramyl dipeptide (MDP). Intracellur immunostaining of porcine

NOD2-expressing cells with this antibody shows that porcine NOD2 is located in the cytosol and also appeared enriched

close to the cell membrane. Thisantibody serve as powerful tools for biochemical and immunohistochemical analyzes of

porcine NOD2 and for understanding the mechanisms of NOD2-mediated immune system in pigs.

Specificity]

Porcine NOD2

Cross reactivity]

Reacts with porcine. Not yet tested in other species.

Application notes Recommended dilutions : ・ Immunohistochemistry: 1/25-1/500

・ Flow cytometry: 1/50-1/500

・ Western blotting: 1/25-1/500

Other applications have not been tested.

Optimal dilutions/concentrations should be determined by the end user.