Application: WB, ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Protein Description: nuclear factor I/B
Gene Name: NFIB
Alternative Gene Name: NFI-RED, NFIB2, NFIB3
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000008575: 99%, ENSRNOG00000009795: 99%
Entrez Gene ID: 4781
Uniprot ID: O00712
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Protein Description: nuclear factor I/B
Gene Name: NFIB
Alternative Gene Name: NFI-RED, NFIB2, NFIB3
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000008575: 99%, ENSRNOG00000009795: 99%
Entrez Gene ID: 4781
Uniprot ID: O00712
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Cognate Antibody/Antigen for Anti NFIB pAb (ATL-HPA003956) | |
Antigen | PrEST Antigen NFIB (ATL-APrEST86703) |
Documents & Links for Anti NFIB pAb (ATL-HPA003956) | |
Datasheet | Anti NFIB pAb (ATL-HPA003956) Datasheet (External Link) |
Vendor Page | Anti NFIB pAb (ATL-HPA003956) at Atlas |
Documents & Links for Anti NFIB pAb (ATL-HPA003956) | |
Datasheet | Anti NFIB pAb (ATL-HPA003956) Datasheet (External Link) |
Vendor Page | Anti NFIB pAb (ATL-HPA003956) |
Citations for Anti NFIB pAb (ATL-HPA003956) – 17 Found |
A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma. Cancer Discov. 2015 Sep;5(9):920-31. doi: 10.1158/2159-8290.CD-15-0125. Epub 2015 Jun 17. PubMed |
Nfib Regulates Transcriptional Networks That Control the Development of Prostatic Hyperplasia. Endocrinology. 2016 Mar;157(3):1094-109. doi: 10.1210/en.2015-1312. Epub 2015 Dec 17. PubMed |
NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF. EBioMedicine. 2017 Feb;16:63-75. doi: 10.1016/j.ebiom.2017.01.013. Epub 2017 Jan 16. PubMed |
YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis. Nat Commun. 2019 Sep 2;10(1):3914. doi: 10.1038/s41467-019-11884-5. PubMed |
Increased nuclear factor I/B expression in prostate cancer correlates with AR expression. Prostate. 2020 Sep;80(13):1058-1070. doi: 10.1002/pros.24019. Epub 2020 Jul 21. PubMed |
ASCL1 represses a SOX9(+) neural crest stem-like state in small cell lung cancer. Genes Dev. 2021 Jun;35(11-12):847-869. doi: 10.1101/gad.348295.121. Epub 2021 May 20. PubMed |
NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development. J Neurosci. 2014 Feb 19;34(8):2921-30. doi: 10.1523/JNEUROSCI.2319-13.2014. PubMed |
NFI transcription factors interact with FOXA1 to regulate prostate-specific gene expression. Mol Endocrinol. 2014 Jun;28(6):949-64. doi: 10.1210/me.2013-1213. Epub 2014 May 6. PubMed |
MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells. Biol Open. 2014 Jul 25;3(8):741-58. doi: 10.1242/bio.20147765. PubMed |
PAX6 does not regulate Nfia and Nfib expression during neocortical development. Sci Rep. 2015 May 29;5:10668. doi: 10.1038/srep10668. PubMed |
Chromatin Decondensation by FOXP2 Promotes Human Neuron Maturation and Expression of Neurodevelopmental Disease Genes. Cell Rep. 2019 May 7;27(6):1699-1711.e9. doi: 10.1016/j.celrep.2019.04.044. PubMed |
Regionally Distinct Astrocytes Display Unique Transcription Factor Profiles in the Adult Brain. Front Neurosci. 2020 Feb 21;14:61. doi: 10.3389/fnins.2020.00061. eCollection 2020. PubMed |
Combined allelic dosage of Nfia and Nfib regulates cortical development. Brain Neurosci Adv. 2017 Nov 22;1:2398212817739433. doi: 10.1177/2398212817739433. eCollection 2017 Jan-Dec. PubMed |
DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. Elife. 2021 Apr 19;10:e61769. doi: 10.7554/eLife.61769. PubMed |
Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities. Neuron. 2020 Jun 17;106(6):992-1008.e9. doi: 10.1016/j.neuron.2020.03.025. Epub 2020 Apr 21. PubMed |
Redundant and non-redundant cytokine-activated enhancers control Csn1s2b expression in the lactating mouse mammary gland. Nat Commun. 2021 Apr 14;12(1):2239. doi: 10.1038/s41467-021-22500-w. PubMed |
PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development. Breast Cancer Res. 2022 Apr 19;24(1):30. doi: 10.1186/s13058-022-01523-1. PubMed |