Anti-Mincle (Mouse) mAb (Clone: 4A9)

MBL

Catalog No: MBL-D292-3

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Monoclonal antibody of 100 µl targeting CLEC4E for FCM, IPP, WB.

Product Specifications

• Application: FC, IP, WB
• Reactivity: Mouse
• Clonality: Monoclonal IgG1 ĸ
• Host: Rat
• Immunogen: RBL-2H3 cells introduced Mincle mouse full-length protein
• Gene ID - Human:

  26253

• Gene ID - Mouse:

  56619

• Formulation: 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.

Citations for Anti-Mincle (Mouse) mAb (Clone: 4A9) – 7 Found

Yamasaki, Sho; Ishikawa, Eri; Sakuma, Machie; Hara, Hiromitsu; Ogata, Koji; Saito, Takashi. Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nature Immunology. 2008;9(10):1179-88. 
- Comments: Used in: Function

Miyake, Yasunobu; Toyonaga, Kenji; Mori, Daiki; Kakuta, Shigeru; Hoshino, Yoshihiko; Oyamada, Akiko; Yamada, Hisakata; Ono, Ken-Ichiro; Suyama, Mikita; Iwakura, Yoichiro; Yoshikai, Yasunobu; Yamasaki, Sho. C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor. Immunity. 2013;38(5):1050-62. 
- Comments: Used in: FCM

Toyonaga, Kenji; Miyake, Yasunobu; Yamasaki, Sho. Characterization of the receptors for mycobacterial cord factor in Guinea pig. Plos One. 9(2):e88747. 
- Comments: Used in: FCM

Mohanraj, Mahendravarman; Sekar, Ponarulselvam; Liou, Horng-Huei; Chang, Shwu-Fen; Lin, Wan-Wan. The Mycobacterial Adjuvant Analogue TDB Attenuates Neuroinflammation via Mincle-Independent PLC-γ1/PKC/ERK Signaling and Microglial Polarization. Molecular Neurobiology. 2019;56(2):1167-1187. 
- Comments: Used in: WB

Mohanraj, Mahendravarman; Sekar, Ponarulselvam; Liou, Horng-Huei; Chang, Shwu-Fen; Lin, Wan-Wan. The Mycobacterial Adjuvant Analogue TDB Attenuates Neuroinflammation via Mincle-Independent PLC-γ1/PKC/ERK Signaling and Microglial Polarization. Molecular Neurobiology. 2019;56(2):1167-1187. 
- Comments: Used in: FCM

Fites, J Scott; Gui, Michael; Kernien, John F; Negoro, Paige; Dagher, Zeina; Sykes, David B; Nett, Jeniel E; Mansour, Michael K; Klein, Bruce S. An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections. Plos Pathogens. 2018;14(5):e1007073. 
- Comments: Used in: FCM

Tan, Rui-Zhi; Liu, Jian; Zhang, Ying-Ying; Wang, Hong-Lian; Li, Jian-Chun; Liu, Yu-Hang; Zhong, Xia; Zhang, Yu-Wei; Yan, Ying; Lan, Hui-Yao; Wang, Li. Curcumin relieved cisplatin-induced kidney inflammation through inhibiting Mincle-maintained M1 macrophage phenotype. Phytomedicine : International Journal Of Phytotherapy And Phytopharmacology. 2019;52:284-294. 
- Comments: Used in: WB