Macrophage-inducible C-type lectin (Mincle, also called as Clec4e and Clecsf9), a type II transmembrane C-type lectin receptor, is expressed mainly in macrophages. Mincle is selectively associated with the Fc receptor common g-chain which contains immunoreceptor tyrosine-based activation motif (ITAM) and activates macrophages to produce inflammatory cytokines and chemokines.
Monoclonal antibody conjugated to biotin of 100 µl targeting Mincle for FCM.
| Product Specifications |
| Application |
FC |
| Reactivity |
Mouse |
| Clonality |
Monoclonal IgG1 ĸ |
| Host |
Rat |
| Immunogen |
RBL-2H3 cells expressing full length mouse mincle |
| Formulation |
PBS (pH 7.2) containing 1% BSA and 0.1% ProClin 150 |
