Application: WB, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
| Documents & Links for Anti MEN1 mAb (Clone 8G11) | |
| Datasheet | Anti MEN1 mAb (Clone 8G11) Datasheet |
| Vendor Page | Anti MEN1 mAb (Clone 8G11) at CUSABIO |
| Documents & Links for Anti MEN1 mAb (Clone 8G11) | |
| Datasheet | Anti MEN1 mAb (Clone 8G11) Datasheet |
| Vendor Page | Anti MEN1 mAb (Clone 8G11) |
