Application: IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
| Documents & Links for Anti MAPT mAb (Clone 4A1) | |
| Datasheet | Anti MAPT mAb (Clone 4A1) Datasheet |
| Vendor Page | Anti MAPT mAb (Clone 4A1) at CUSABIO |
| Documents & Links for Anti MAPT mAb (Clone 4A1) | |
| Datasheet | Anti MAPT mAb (Clone 4A1) Datasheet |
| Vendor Page | Anti MAPT mAb (Clone 4A1) |
