Application: IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.
| Documents & Links for Anti LRRK2 mAb (Clone 4E9) | |
| Datasheet | Anti LRRK2 mAb (Clone 4E9) Datasheet |
| Vendor Page | Anti LRRK2 mAb (Clone 4E9) at CUSABIO |
| Documents & Links for Anti LRRK2 mAb (Clone 4E9) | |
| Datasheet | Anti LRRK2 mAb (Clone 4E9) Datasheet |
| Vendor Page | Anti LRRK2 mAb (Clone 4E9) |
