Anti-LC3 pAb

Catalog No:
MBL-PM036
$416.00
This LC3 antibody is validated for multiple applications (WB, IHC, ICC and IP) and isoform detection. PM036 has more than 1,000 citations where it used to generate data showing autophagy in research papers.  (Saitoh T et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 456, 264-8 (2008)). This is a polyclonal antibody that is raised in rabbit and is reactive with human, hamster, mouse, rat.  

Product Specifications
ApplicationFCM, ICC, IP, WB, IHC
ReactivityHuman, Mouse, Rat, Hamster, Zebrafish
ClonalityPolyclonal
HostRabbit
ImmunogenRecombinant human LC3 (MAP1LC3B :1-120 a.a.)
FormulationPBS/50% glycerol, pH 7.2

Citations for Anti-LC3 pAb – 152 Found
Saitoh, Tatsuya; Fujita, Naonobu; Jang, Myoung Ho; Uematsu, Satoshi; Yang, Bo-Gie; Satoh, Takashi; Omori, Hiroko; Noda, Takeshi; Yamamoto, Naoki; Komatsu, Masaaki; Tanaka, Keiji; Kawai, Taro; Tsujimura, Tohru; Takeuchi, Osamu; Yoshimori, Tamotsu; Akira, Shizuo. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature. 2008;456(7219):264-8.  PubMed
Comments: Used in: WB
Katona, Istvan; Zhang, Xuebao; Bai, Yunhong; Shy, Michael E; Guo, Jiasong; Yan, Qing; Hatfield, James; Kupsky, William J; Li, Jun. Distinct pathogenic processes between Fig4-deficient motor and sensory neurons. The European Journal Of Neuroscience. 2011;33(8):1401-10.  PubMed
Comments: Used in: WB
Wu, Ya-Na; Yang, Li-Xing; Shi, Xuan-Yu; Li, I-Chen; Biazik, Joanna M; Ratinac, Kyle R; Chen, Dong-Hwang; Thordarson, Pall; Shieh, Dar-Bin; Braet, Filip. The selective growth inhibition of oral cancer by iron core-gold shell nanoparticles through mitochondria-mediated autophagy. Biomaterials. 2011;32(20):4565-73.  PubMed
Comments: Used in: ICC
Lee, Eun-Ju; Tournier, Cathy. The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy. Autophagy. 2011;7(7):689-95.  PubMed
Comments: Used in: WB
Pan, Ji-An; Ullman, Erica; Dou, Zhixun; Zong, Wei-Xing. Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranes. Molecular And Cellular Biology. 2011;31(15):3158-70.  PubMed
Comments: Used in: WB
Huang, Ying; Hou, Jia-Kai; Chen, Ting-Ting; Zhao, Xu-Yun; Yan, Zhao-Wen; Zhang, Jing; Yang, Jie; Kogan, Scott C; Chen, Guo-Qiang. PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway. Autophagy. 2011;7(10):1132-44.  PubMed
Comments: Used in: WB
Hasui, Kazuhisa; Wang, Jia; Jia, Xinshan; Tanaka, Masashi; Nagai, Taku; Matsuyama, Takami; Eizuru, Yoshito. Enhanced Autophagy and Reduced Expression of Cathepsin D Are Related to Autophagic Cell Death in Epstein-Barr Virus-Associated Nasal Natural Killer/T-Cell Lymphomas: An Immunohistochemical Analysis of Beclin-1, LC3, Mitochondria (AE-1), and Cathepsin D in Nasopharyngeal Lymphomas. Acta Histochemica Et Cytochemica. 2011;44(3):119-31.  PubMed
Comments: Used in: IHC
Miranda, Soledad; González-Rodríguez, Águeda; García-Ramírez, Marta; Revuelta-Cervantes, Jesús; Hernández, Cristina; Simó, Rafael; Valverde, Ángela M. Beneficial effects of fenofibrate in retinal pigment epithelium by the modulation of stress and survival signaling under diabetic conditions. Journal Of Cellular Physiology. 2012;227(6):2352-62.  PubMed
Comments: Used in: WB
Otomo, Takanobu; Higaki, Katsumi; Nanba, Eiji; Ozono, Keiichi; Sakai, Norio. Lysosomal storage causes cellular dysfunction in mucolipidosis II skin fibroblasts. The Journal Of Biological Chemistry. 2011;286(40):35283-90.  PubMed
Comments: Used in: WB
Yan, Jun; Li, Qing-Fang; Wang, Li-Sheng; Wang, Hua; Xiao, Feng-Jun; Yang, Yue-Feng; Wu, Chu-Tse. Methyl-β-cyclodextrin induces programmed cell death in chronic myeloid leukemia cells and, combined with imatinib, produces a synergistic downregulation of ERK/SPK1 signaling. Anti-Cancer Drugs. 2012;23(1):22-31.  PubMed
Comments: Used in: WB
Yan, Jun; Li, Qing-Fang; Wang, Li-Sheng; Wang, Hua; Xiao, Feng-Jun; Yang, Yue-Feng; Wu, Chu-Tse. Methyl-β-cyclodextrin induces programmed cell death in chronic myeloid leukemia cells and, combined with imatinib, produces a synergistic downregulation of ERK/SPK1 signaling. Anti-Cancer Drugs. 2012;23(1):22-31.  PubMed
Comments: Used in: ICC
Takaesu, Giichi; Kobayashi, Takashi; Yoshimura, Akihiko. TGFβ-activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy. Journal Of Biochemistry. 2012;151(2):157-66.  PubMed
Comments: Used in: WB
Taguwa, Shuhei; Kambara, Hiroto; Fujita, Naonobu; Noda, Takeshi; Yoshimori, Tamotsu; Koike, Kazuhiko; Moriishi, Kohji; Matsuura, Yoshiharu. Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus. Journal Of Virology. 2011;85(24):13185-94.  PubMed
Comments: Used in: WB
Taguwa, Shuhei; Kambara, Hiroto; Fujita, Naonobu; Noda, Takeshi; Yoshimori, Tamotsu; Koike, Kazuhiko; Moriishi, Kohji; Matsuura, Yoshiharu. Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus. Journal Of Virology. 2011;85(24):13185-94.  PubMed
Comments: Used in: ICC
Xu, Teng; Su, Hang; Ganapathy, Suthakar; Yuan, Zhi-Min. Modulation of autophagic activity by extracellular pH. Autophagy. 2011;7(11):1316-22.  PubMed
Comments: Used in: WB
Rasmussen, Simon B; Horan, Kristy A; Holm, Christian K; Stranks, Amanda J; Mettenleiter, Thomas C; Simon, A Katharina; Jensen, Søren B; Rixon, Frazer J; He, Bin; Paludan, Søren R. Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes. Journal Of Immunology (Baltimore, Md. : 1950). 2011;187(10):5268-76.  PubMed
Comments: Used in: WB
Rasmussen, Simon B; Horan, Kristy A; Holm, Christian K; Stranks, Amanda J; Mettenleiter, Thomas C; Simon, A Katharina; Jensen, Søren B; Rixon, Frazer J; He, Bin; Paludan, Søren R. Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes. Journal Of Immunology (Baltimore, Md. : 1950). 2011;187(10):5268-76.  PubMed
Comments: Used in: ICC
Wu, Shan-Ying; Lan, Sheng-Hui; Cheng, Da-En; Chen, Wei-Kai; Shen, Cheng-Huang; Lee, Ying-Ray; Zuchini, Roberto; Liu, Hsiao-Sheng. Ras-related tumorigenesis is suppressed by BNIP3-mediated autophagy through inhibition of cell proliferation. Neoplasia (New York, N.y.). 2011;13(12):1171-82.  PubMed
Comments: Used in: WB
Starr, Tregei; Child, Robert; Wehrly, Tara D; Hansen, Bryan; Hwang, Seungmin; López-Otin, Carlos; Virgin, Herbert W; Celli, Jean. Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle. Cell Host & Microbe. 2012;11(1):33-45.  PubMed
Comments: Used in: WB
Starr, Tregei; Child, Robert; Wehrly, Tara D; Hansen, Bryan; Hwang, Seungmin; López-Otin, Carlos; Virgin, Herbert W; Celli, Jean. Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle. Cell Host & Microbe. 2012;11(1):33-45.  PubMed
Comments: Used in: ICC
Kaini, Ramesh R; Sillerud, Laurel O; Zhaorigetu, Siqin; Hu, Chien-An A. Autophagy regulates lipolysis and cell survival through lipid droplet degradation in androgen-sensitive prostate cancer cells. The Prostate. 2012;72(13):1412-22.  PubMed
Comments: Used in: WB
Yu, Xin; Ajayi, Abiodun; Boga, Narasimha Rao; Ström, Anna-Lena. Differential degradation of full-length and cleaved ataxin-7 fragments in a novel stable inducible SCA7 model. Journal Of Molecular Neuroscience : Mn. 2012;47(2):219-33.  PubMed
Comments: Used in: WB
Niizuma, Shinichiro; Inuzuka, Yasutaka; Okuda, Junji; Kato, Takao; Kawashima, Tsuneaki; Tamaki, Yodo; Iwanaga, Yoshitaka; Yoshida, Yuki; Kosugi, Rie; Watanabe-Maeda, Kayo; Machida, Yoji; Tsuji, Shingo; Aburatani, Hiroyuki; Izumi, Tohru; Kita, Toru; Kimura, Takeshi; Shioi, Tetsuo. Effect of persistent activation of phosphoinositide 3-kinase on heart. Life Sciences. 2012;90(15-16):619-28.  PubMed
Comments: Used in: WB
Seillier, M; Peuget, S; Gayet, O; Gauthier, C; N'Guessan, P; Monte, M; Carrier, A; Iovanna, J L; Dusetti, N J. TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death. Cell Death And Differentiation. 2012;19(9):1525-35.  PubMed
Comments: Used in: ICC
Kaminskyy, Vitaliy O; Piskunova, Tatiana; Zborovskaya, Irina B; Tchevkina, Elena M; Zhivotovsky, Boris. Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation. Autophagy. 2012;8(7):1032-44.  PubMed
Comments: Used in: WB
Kaminskyy, Vitaliy O; Piskunova, Tatiana; Zborovskaya, Irina B; Tchevkina, Elena M; Zhivotovsky, Boris. Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation. Autophagy. 2012;8(7):1032-44.  PubMed
Comments: Used in: ICC
Botbol, Yair; Patel, Bindi; Macian, Fernando. Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation. Autophagy. 11(10):1864-77.  PubMed
Comments: Used in: WB
Botbol, Yair; Patel, Bindi; Macian, Fernando. Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation. Autophagy. 11(10):1864-77.  PubMed
Comments: Used in: IP
Botbol, Yair; Patel, Bindi; Macian, Fernando. Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation. Autophagy. 11(10):1864-77.  PubMed
Comments: Used in: ICC
Botbol, Yair; Macian, Fernando. Assays for Monitoring Macroautophagy Activity in T cells. Methods In Molecular Biology (Clifton, N.j.). 1343:143-53.  PubMed
Comments: Used in: WB
Botbol, Yair; Macian, Fernando. Assays for Monitoring Macroautophagy Activity in T cells. Methods In Molecular Biology (Clifton, N.j.). 1343:143-53.  PubMed
Comments: Used in: ICC
Cherepkova, M Y; Sineva, G S; Pospelov, V A. Leukemia inhibitory factor (LIF) withdrawal activates mTOR signaling pathway in mouse embryonic stem cells through the MEK/ERK/TSC2 pathway. Cell Death & Disease. 2016;7(1):e2050.  PubMed
Comments: Used in: ICC
Guo, Jing L; Buist, Arjan; Soares, Alberto; Callaerts, Kathleen; Calafate, Sara; Stevenaert, Frederik; Daniels, Joshua P; Zoll, Bryan E; Crowe, Alex; Brunden, Kurt R; Moechars, Diederik; Lee, Virginia M Y. The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES. The Journal Of Biological Chemistry. 2016;291(25):13175-93.  PubMed
Comments: Used in: WB
Guo, Jing L; Buist, Arjan; Soares, Alberto; Callaerts, Kathleen; Calafate, Sara; Stevenaert, Frederik; Daniels, Joshua P; Zoll, Bryan E; Crowe, Alex; Brunden, Kurt R; Moechars, Diederik; Lee, Virginia M Y. The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES. The Journal Of Biological Chemistry. 2016;291(25):13175-93.  PubMed
Comments: Used in: ICC
Sano, Osamu; Kazetani, Kenichi; Funata, Masaaki; Fukuda, Yasunori; Matsui, Junji; Iwata, Hidehisa. Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition. Febs Letters. 2016;590(11):1576-85.  PubMed
Comments: Used in: WB
Fujita, Naonobu; Huang, Wilson; Lin, Tzu-Han; Groulx, Jean-Francois; Jean, Steve; Nguyen, Jen; Kuchitsu, Yoshihiko; Koyama-Honda, Ikuko; Mizushima, Noboru; Fukuda, Mitsunori; Kiger, Amy A. Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. Elife. 2017;6  PubMed
Fujita, Naonobu; Huang, Wilson; Lin, Tzu-Han; Groulx, Jean-Francois; Jean, Steve; Nguyen, Jen; Kuchitsu, Yoshihiko; Koyama-Honda, Ikuko; Mizushima, Noboru; Fukuda, Mitsunori; Kiger, Amy A. Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. Elife. 2017;6  PubMed
Comments: Used in: WB
Fujita, Naonobu; Huang, Wilson; Lin, Tzu-Han; Groulx, Jean-Francois; Jean, Steve; Nguyen, Jen; Kuchitsu, Yoshihiko; Koyama-Honda, Ikuko; Mizushima, Noboru; Fukuda, Mitsunori; Kiger, Amy A. Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. Elife. 2017;6  PubMed
Comments: Used in: ICC
Girault, Virginie; Gilard, Vianney; Marguet, Florent; Lesueur, Céline; Hauchecorne, Michelle; Ramdani, Yasmina; Laquerrière, Annie; Marret, Stéphane; Jégou, Sylvie; Gonzalez, Bruno Jose; Brasse-Lagnel, Carole; Bekri, Soumeya. Prenatal alcohol exposure impairs autophagy in neonatal brain cortical microvessels. Cell Death & Disease. 2017;8(2):e2610.  PubMed
Comments: Used in: ICC
Girault, Virginie; Gilard, Vianney; Marguet, Florent; Lesueur, Céline; Hauchecorne, Michelle; Ramdani, Yasmina; Laquerrière, Annie; Marret, Stéphane; Jégou, Sylvie; Gonzalez, Bruno Jose; Brasse-Lagnel, Carole; Bekri, Soumeya. Prenatal alcohol exposure impairs autophagy in neonatal brain cortical microvessels. Cell Death & Disease. 2017;8(2):e2610.  PubMed
Comments: Used in: IHC
Cao, Mian; Wu, Yumei; Ashrafi, Ghazaleh; McCartney, Amber J; Wheeler, Heather; Bushong, Eric A; Boassa, Daniela; Ellisman, Mark H; Ryan, Timothy A; De Camilli, Pietro. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017;93(4):882-896.e5.  PubMed
Comments: Used in: WB
Taguchi, Yuki; Horiuchi, Yuta; Kano, Fumi; Murata, Masayuki. Novel prosurvival function of Yip1A in human cervical cancer cells: constitutive activation of the IRE1 and PERK pathways of the unfolded protein response. Cell Death & Disease. 2017;8(3):e2718.  PubMed
Comments: Used in: WB
Chen, Liqun; Wang, Ke; Long, Aijun; Jia, Liangjie; Zhang, Yuanyuan; Deng, Haiteng; Li, Yu; Han, Jinbo; Wang, Yiguo. Fasting-induced hormonal regulation of lysosomal function. Cell Research. 2017;27(6):748-763.  PubMed
Comments: Used in: WB
Sakamoto, Shuichiro; Miyara, Masatsugu; Sanoh, Seigo; Ohta, Shigeru; Kotake, Yaichiro. Mild MPP(+) exposure-induced glucose starvation enhances autophagosome synthesis and impairs its degradation. Scientific Reports. 2017;7:46668.  PubMed
Comments: Used in: WB
Arasaki, Kohei; Mikami, Yumi; Shames, Stephanie R; Inoue, Hiroki; Wakana, Yuichi; Tagaya, Mitsuo. Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17. Nature Communications. 2017;8:15406.  PubMed
Comments: Used in: WB
Takahashi, Kenichi; Mashima, Hirosato; Miura, Kouichi; Maeda, Daichi; Goto, Akiteru; Goto, Takashi; Sun-Wada, Ge-Hong; Wada, Yoh; Ohnishi, Hirohide. Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models. Scientific Reports. 2017;7(1):2817.  PubMed
Comments: Used in: WB
Kim, Tae Sung; Shin, Yern-Hyerk; Lee, Hye-Mi; Kim, Jin Kyung; Choe, Jin Ho; Jang, Ji-Chan; Um, Soohyun; Jin, Hyo Sun; Komatsu, Masaaki; Cha, Guang-Ho; Chae, Han-Jung; Oh, Dong-Chan; Jo, Eun-Kyeong. Ohmyungsamycins promote antimicrobial responses through autophagy activation via AMP-activated protein kinase pathway. Scientific Reports. 2017;7(1):3431.  PubMed
Comments: Used in: ICC
Hori, Ikumi; Otomo, Takanobu; Nakashima, Mitsuko; Miya, Fuyuki; Negishi, Yutaka; Shiraishi, Hideaki; Nonoda, Yutaka; Magara, Shinichi; Tohyama, Jun; Okamoto, Nobuhiko; Kumagai, Takeshi; Shimoda, Konomi; Yukitake, Yoshiya; Kajikawa, Daigo; Morio, Tomohiro; Hattori, Ayako; Nakagawa, Motoo; Ando, Naoki; Nishino, Ichizo; Kato, Mitsuhiro; Tsunoda, Tatsuhiko; Saitsu, Hirotomo; Kanemura, Yonehiro; Yamasaki, Mami; Kosaki, Kenjiro; Matsumoto, Naomichi; Yoshimori, Tamotsu; Saitoh, Shinji. Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement. Scientific Reports. 2017;7(1):3552.  PubMed
Comments: Used in: WB
Hori, Ikumi; Otomo, Takanobu; Nakashima, Mitsuko; Miya, Fuyuki; Negishi, Yutaka; Shiraishi, Hideaki; Nonoda, Yutaka; Magara, Shinichi; Tohyama, Jun; Okamoto, Nobuhiko; Kumagai, Takeshi; Shimoda, Konomi; Yukitake, Yoshiya; Kajikawa, Daigo; Morio, Tomohiro; Hattori, Ayako; Nakagawa, Motoo; Ando, Naoki; Nishino, Ichizo; Kato, Mitsuhiro; Tsunoda, Tatsuhiko; Saitsu, Hirotomo; Kanemura, Yonehiro; Yamasaki, Mami; Kosaki, Kenjiro; Matsumoto, Naomichi; Yoshimori, Tamotsu; Saitoh, Shinji. Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement. Scientific Reports. 2017;7(1):3552.  PubMed
Comments: Used in: ICC
Lu, Shiou-Ling; Kawabata, Tsuyoshi; Cheng, Yi-Lin; Omori, Hiroko; Hamasaki, Maho; Kusaba, Tatsuya; Iwamoto, Ryo; Arimoto, Hirokazu; Noda, Takeshi; Lin, Yee-Shin; Yoshimori, Tamotsu. Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes. Plos Pathogens. 2017;13(7):e1006444.  PubMed
Comments: Used in: WB
Lu, Shiou-Ling; Kawabata, Tsuyoshi; Cheng, Yi-Lin; Omori, Hiroko; Hamasaki, Maho; Kusaba, Tatsuya; Iwamoto, Ryo; Arimoto, Hirokazu; Noda, Takeshi; Lin, Yee-Shin; Yoshimori, Tamotsu. Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes. Plos Pathogens. 2017;13(7):e1006444.  PubMed
Comments: Used in: ICC
Ono, Akito; Sano, Osamu; Kazetani, Ken-Ichi; Muraki, Takamichi; Imamura, Keisuke; Sumi, Hiroyuki; Matsui, Junji; Iwata, Hidehisa. Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition. Plos One. 12(7):e0181243.  PubMed
Comments: Used in: WB
Ono, Akito; Sano, Osamu; Kazetani, Ken-Ichi; Muraki, Takamichi; Imamura, Keisuke; Sumi, Hiroyuki; Matsui, Junji; Iwata, Hidehisa. Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition. Plos One. 12(7):e0181243.  PubMed
Comments: Used in: ICC
Chen, Ying-Da; Fang, Yi-Ting; Cheng, Yi-Lin; Lin, Chiou-Feng; Hsu, Li-Jin; Wang, Shu-Ying; Anderson, Robert; Chang, Chih-Peng; Lin, Yee-Shin. Exophagy of annexin A2 via RAB11, RAB8A and RAB27A in IFN-γ-stimulated lung epithelial cells. Scientific Reports. 2017;7(1):5676.  PubMed
Comments: Used in: ICC
Cheng, Yi-Lin; Wu, Yan-Wei; Kuo, Chih-Feng; Lu, Shiou-Ling; Liu, Fu-Tong; Anderson, Robert; Lin, Chiou-Feng; Liu, Yi-Ling; Wang, Wan-Yu; Chen, Ying-Da; Zheng, Po-Xing; Wu, Jiunn-Jong; Lin, Yee-Shin. Galectin-3 Inhibits Galectin-8/Parkin-Mediated Ubiquitination of Group A Streptococcus. Mbio. 2017;8(4)  PubMed
Comments: Used in: ICC
Kjos, Ingrid; Borg Distefano, Marita; Sætre, Frank; Repnik, Urska; Holland, Petter; Jones, Arwyn T; Engedal, Nikolai; Simonsen, Anne; Bakke, Oddmund; Progida, Cinzia. Rab7b modulates autophagic flux by interacting with Atg4B. Embo Reports. 2017;18(10):1727-1739.  PubMed
Comments: Used in: ICC
Anzai, Erina; Hirata, Kensuke; Shibazaki, Misato; Yamada, Chiaki; Morii, Mariko; Honda, Takuya; Yamaguchi, Naoto; Yamaguchi, Noritaka. FOXA1 Induces E-Cadherin Expression at the Protein Level via Suppression of Slug in Epithelial Breast Cancer Cells. Biological & Pharmaceutical Bulletin. 40(9):1483-1489.  PubMed
Comments: Used in: WB
Zhao, Qiong; Hu, Zhan-Ying; Zhang, Jing-Pu; Jiang, Jian-Dong; Ma, Yuan-Yuan; Li, Jian-Rui; Peng, Zong-Gen; Chen, Jin-Hua. Dual Roles of Two Isoforms of Autophagy-related Gene ATG10 in HCV-Subgenomic replicon Mediated Autophagy Flux and Innate Immunity. Scientific Reports. 2017;7(1):11250.  PubMed
Comments: Used in: WB
Meng, Xiang-Hui; Chen, Bo; Zhang, Jing-Pu. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. International Journal Of Biological Sciences. 13(8):985-995.  PubMed
Comments: Used in: WB
Meng, Xiang-Hui; Chen, Bo; Zhang, Jing-Pu. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. International Journal Of Biological Sciences. 13(8):985-995.  PubMed
Comments: Used in: ICC
Wang, Ying; Subramanian, Manikandan; Yurdagul, Arif Jr; Barbosa-Lorenzi, Valéria C; Cai, Bishuang; de Juan-Sanz, Jaime; Ryan, Timothy A; Nomura, Masatoshi; Maxfield, Frederick R; Tabas, Ira. Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages. Cell. 2017;171(2):331-345.e22.  PubMed
Comments: Used in: ICC
Sato, Yusuke; Ohtsubo, Hideaki; Nihei, Naohiro; Kaneko, Takane; Sato, Yoriko; Adachi, Shin-Ichi; Kondo, Shinji; Nakamura, Mako; Mizunoya, Wataru; Iida, Hiroshi; Tatsumi, Ryuichi; Rada, Cristina; Yoshizawa, Fumiaki. Apobec2 deficiency causes mitochondrial defects and mitophagy in skeletal muscle. Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology. 2018;32(3):1428-1439.  PubMed
Comments: Used in: WB
Lee, Pamela P; Lobato-Márquez, Damián; Pramanik, Nayani; Sirianni, Andrea; Daza-Cajigal, Vanessa; Rivers, Elizabeth; Cavazza, Alessia; Bouma, Gerben; Moulding, Dale; Hultenby, Kjell; Westerberg, Lisa S; Hollinshead, Michael; Lau, Yu-Lung; Burns, Siobhan O; Mostowy, Serge; Bajaj-Elliott, Mona; Thrasher, Adrian J. Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells. Nature Communications. 2017;8(1):1576.  PubMed
Comments: Used in: WB
Lee, Pamela P; Lobato-Márquez, Damián; Pramanik, Nayani; Sirianni, Andrea; Daza-Cajigal, Vanessa; Rivers, Elizabeth; Cavazza, Alessia; Bouma, Gerben; Moulding, Dale; Hultenby, Kjell; Westerberg, Lisa S; Hollinshead, Michael; Lau, Yu-Lung; Burns, Siobhan O; Mostowy, Serge; Bajaj-Elliott, Mona; Thrasher, Adrian J. Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells. Nature Communications. 2017;8(1):1576.  PubMed
Comments: Used in: ICC
Yanagisawa, Hiroko; Ishii, Tomohiro; Endo, Kentaro; Kawakami, Emiko; Nagao, Kazuaki; Miyashita, Toshiyuki; Akiyama, Keiko; Watabe, Kazuhiko; Komatsu, Masaaki; Yamamoto, Daisuke; Eto, Yoshikatsu. L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease. Scientific Reports. 2017;7(1):15944.  PubMed
Comments: Used in: WB
Yanagisawa, Hiroko; Ishii, Tomohiro; Endo, Kentaro; Kawakami, Emiko; Nagao, Kazuaki; Miyashita, Toshiyuki; Akiyama, Keiko; Watabe, Kazuhiko; Komatsu, Masaaki; Yamamoto, Daisuke; Eto, Yoshikatsu. L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease. Scientific Reports. 2017;7(1):15944.  PubMed
Comments: Used in: ICC
Hsieh, Chang-Heng; Wang, Jing-Ping; Chiu, Chien-Chih; Liu, Chun-Yen; Yao, Ching-Fa; Fang, Kang. A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells. Apoptosis : An International Journal On Programmed Cell Death. 2018;23(1):1-15.  PubMed
Comments: Used in: WB
Prieto-Domínguez, Néstor; Méndez-Blanco, Carolina; Carbajo-Pescador, Sara; Fondevila, Flavia; García-Palomo, Andrés; González-Gallego, Javier; Mauriz, José L. Melatonin enhances sorafenib actions in human hepatocarcinoma cells by inhibiting mTORC1/p70S6K/HIF-1α and hypoxia-mediated mitophagy. Oncotarget. 2017;8(53):91402-91414.  PubMed
Comments: Used in: WB
Mizunoe, Yuhei; Kobayashi, Masaki; Sudo, Yuka; Watanabe, Shukoh; Yasukawa, Hiromine; Natori, Daiki; Hoshino, Ayana; Negishi, Arisa; Okita, Naoyuki; Komatsu, Masaaki; Higami, Yoshikazu. Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways. Redox Biology. 2018;15:115-124.  PubMed
Comments: Used in: WB
Festa, Beatrice Paola; Chen, Zhiyong; Berquez, Marine; Debaix, Huguette; Tokonami, Natsuko; Prange, Jenny Ann; Hoek, Glenn van de; Alessio, Cremonesi; Raimondi, Andrea; Nevo, Nathalie; Giles, Rachel H; Devuyst, Olivier; Luciani, Alessandro. Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney. Nature Communications. 2018;9(1):161.  PubMed
Comments: Used in: WB
Hsu, Cynthia L; Lee, Elian X; Gordon, Kara L; Paz, Edwin A; Shen, Wen-Chuan; Ohnishi, Kohta; Meisenhelder, Jill; Hunter, Tony; La Spada, Albert R. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nature Communications. 2018;9(1):942.  PubMed
Comments: Used in: ICC
Chu, Jiaqi; Fu, Yuanyuan; Xu, Jiecheng; Zheng, Xueping; Gu, Qianqian; Luo, Xia; Dai, Qi; Zhang, Shuxian; Liu, Peiqing; Hong, Liang; Li, Min. ATG4B inhibitor FMK-9a induces autophagy independent on its enzyme inhibition. Archives Of Biochemistry And Biophysics. 2018;644:29-36.  PubMed
Comments: Used in: WB
Kaneko, Hiroki; Kobayashi, Masaki; Mizunoe, Yuhei; Yoshida, Maho; Yasukawa, Hiromine; Hoshino, Shunsuke; Itagawa, Rei; Furuichi, Takuma; Okita, Naoyuki; Sudo, Yuka; Imae, Masato; Higami, Yoshikazu. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 2018;50(5):527-535.  PubMed
Comments: Used in: WB
Qi, Mengfan; Tian, Ye; Li, Wang; Li, Dan; Zhao, Tian; Yang, Yuxin; Li, Qiwen; Chen, Sujun; Yang, Yan; Zhang, Zhixiong; Tang, Liang; Liu, Zhonghua; Su, Bo; Li, Fei; Feng, Yonghong; Fei, Ke; Zhang, Peng; Zhang, Fan; Zhang, Lei. ERK inhibition represses gefitinib resistance in non-small cell lung cancer cells. Oncotarget. 2018;9(15):12020-12034.  PubMed
Comments: Used in: IHC
Sun, Yan; Huang, Yong-Hao; Huang, Feng-Ying; Mei, Wen-Li; Liu, Quan; Wang, Cai-Chun; Lin, Ying-Ying; Huang, Canhua; Li, Yue-Nan; Dai, Hao-Fu; Tan, Guang-Hong. 3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells. Theranostics. 8(7):2044-2060.  PubMed
Comments: Used in: WB
Sun, Yan; Huang, Yong-Hao; Huang, Feng-Ying; Mei, Wen-Li; Liu, Quan; Wang, Cai-Chun; Lin, Ying-Ying; Huang, Canhua; Li, Yue-Nan; Dai, Hao-Fu; Tan, Guang-Hong. 3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells. Theranostics. 8(7):2044-2060.  PubMed
Comments: Used in: ICC
El-Darawish, Yosif; Li, Wen; Yamanishi, Kyosuke; Pencheva, Magdalena; Oka, Naoto; Yamanishi, Hiromichi; Matsuyama, Tomohiro; Tanaka, Yoshimasa; Minato, Nagahiro; Okamura, Haruki. Frontline Science: IL-18 primes murine NK cells for proliferation by promoting protein synthesis, survival, and autophagy. Journal Of Leukocyte Biology. 2018;104(2):253-264.  PubMed
Comments: Used in: WB
El-Darawish, Yosif; Li, Wen; Yamanishi, Kyosuke; Pencheva, Magdalena; Oka, Naoto; Yamanishi, Hiromichi; Matsuyama, Tomohiro; Tanaka, Yoshimasa; Minato, Nagahiro; Okamura, Haruki. Frontline Science: IL-18 primes murine NK cells for proliferation by promoting protein synthesis, survival, and autophagy. Journal Of Leukocyte Biology. 2018;104(2):253-264.  PubMed
Comments: Used in: ICC
Ko, Po-Yen; Yang, Cheng-Chang; Kuo, Yao-Lung; Su, Fong-Chin; Hsu, Tai-I; Tu, Yuan-Kun; Jou, I-Ming. Schwann-Cell Autophagy, Functional Recovery, and Scar Reduction After Peripheral Nerve Repair. Journal Of Molecular Neuroscience : Mn. 2018;64(4):601-610.  PubMed
Comments: Used in: IHC
Raulien, Nora; Friedrich, Kathleen; Strobel, Sarah; Rubner, Stefan; Baumann, Sven; von Bergen, Martin; Körner, Antje; Krueger, Martin; Rossol, Manuela; Wagner, Ulf. Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes. Frontiers In Immunology. 8:609.  PubMed
Comments: Used in: ICC
Chen, Bo; Zheng, Yang-Min; Zhang, Jing-Pu. Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish. Frontiers In Endocrinology. 9:366.  PubMed
Comments: Used in: WB
Härtlova, Anetta; Herbst, Susanne; Peltier, Julien; Rodgers, Angela; Bilkei-Gorzo, Orsolya; Fearns, Antony; Dill, Brian D; Lee, Heyne; Flynn, Rowan; Cowley, Sally A; Davies, Paul; Lewis, Patrick A; Ganley, Ian G; Martinez, Jennifer; Alessi, Dario R; Reith, Alastair D; Trost, Matthias; Gutierrez, Maximiliano G. LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. The Embo Journal. 2018;37(12)  PubMed
Comments: Used in: ICC
Phadwal, Kanchan; Kurian, Dominic; Salamat, Muhammad Khalid F; MacRae, Vicky E; Diack, Abigail B; Manson, Jean C. Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates. Scientific Reports. 2018;8(1):10004.  PubMed
Comments: Used in: WB
Phadwal, Kanchan; Kurian, Dominic; Salamat, Muhammad Khalid F; MacRae, Vicky E; Diack, Abigail B; Manson, Jean C. Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates. Scientific Reports. 2018;8(1):10004.  PubMed
Comments: Used in: ICC
Alvarez-Garcia, Oscar; Matsuzaki, Tokio; Olmer, Merissa; Miyata, Kohei; Mokuda, Sho; Sakai, Daisuke; Masuda, Koichi; Asahara, Hiroshi; Lotz, Martin K. FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration. Aging Cell. 2018;17(5):e12800.  PubMed
Comments: Used in: IHC
Sun, Yameng; Zhang, Ting; Zhang, Yan; Li, Jinfeng; Jin, Lei; Sun, Yinyi; Shi, Nan; Liu, Kangyong; Sun, Xiaojiang. Ischemic Postconditioning Alleviates Cerebral Ischemia-Reperfusion Injury Through Activating Autophagy During Early Reperfusion in Rats. Neurochemical Research. 2018;43(9):1826-1840.  PubMed
Comments: Used in: WB
Skah, Seham; Richartz, Nina; Duthil, Eva; Gilljam, Karin M; Bindesbøll, Christian; Naderi, Elin Hallan; Eriksen, Agnete B; Ruud, Ellen; Dirdal, Marta M; Simonsen, Anne; Blomhoff, Heidi Kiil. cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53. Oncotarget. 2018;9(54):30434-30449.  PubMed
Comments: Used in: ICC
Bak, Dong-Ho; Na, Jungtae; Choi, Mi Ji; Lee, Byung Chul; Oh, Chang Taek; Kim, Jeom-Yong; Han, Hae Jung; Kim, Moo Joong; Kim, Tae Ho; Kim, Beom Joon. Anti‑apoptotic effects of human placental hydrolysate against hepatocyte toxicity in vivo and in vitro. International Journal Of Molecular Medicine. 2018;42(5):2569-2583.  PubMed
Comments: Used in: WB
Mohamud, Yasir; Qu, Junyan; Xue, Yuan Chao; Liu, Huitao; Deng, Haoyu; Luo, Honglin. CALCOCO2/NDP52 and SQSTM1/p62 differentially regulate coxsackievirus B3 propagation. Cell Death And Differentiation. 2019;26(6):1062-1076.  PubMed
Comments: Used in: WB
Hagio-Izaki, Kanako; Yasunaga, Madoka; Yamaguchi, Masahiro; Kajiya, Hiroshi; Morita, Hiromitsu; Yoneda, Masahiro; Hirofuji, Takao; Ohno, Jun. Lipopolysaccharide induces bacterial autophagy in epithelial keratinocytes of the gingival sulcus. Bmc Cell Biology. 2018;19(1):18.  PubMed
Comments: Used in: WB
Hagio-Izaki, Kanako; Yasunaga, Madoka; Yamaguchi, Masahiro; Kajiya, Hiroshi; Morita, Hiromitsu; Yoneda, Masahiro; Hirofuji, Takao; Ohno, Jun. Lipopolysaccharide induces bacterial autophagy in epithelial keratinocytes of the gingival sulcus. Bmc Cell Biology. 2018;19(1):18.  PubMed
Comments: Used in: ICC
Ashraf, Naila S; Duarte-Silva, Sara; Shaw, Emily D; Maciel, Patrícia; Paulson, Henry L; Teixeira-Castro, Andreia; Costa, Maria do Carmo. Citalopram Reduces Aggregation of ATXN3 in a YAC Transgenic Mouse Model of Machado-Joseph Disease. Molecular Neurobiology. 2019;56(5):3690-3701.  PubMed
Comments: Used in: WB
Jiao, Yan-Na; Wu, Li-Na; Xue, Dong; Liu, Xi-Juan; Tian, Zhi-Hua; Jiang, Shan-Tong; Han, Shu-Yan; Li, Ping-Ping. Marsdenia tenacissima extract induces apoptosis and suppresses autophagy through ERK activation in lung cancer cells. Cancer Cell International. 18:149.  PubMed
Comments: Used in: ICC
Kim, Jin Kyung; Kim, Yi Sak; Lee, Hye-Mi; Jin, Hyo Sun; Neupane, Chiranjivi; Kim, Sup; Lee, Sang-Hee; Min, Jung-Joon; Sasai, Miwa; Jeong, Jae-Ho; Choe, Seong-Kyu; Kim, Jin-Man; Yamamoto, Masahiro; Choy, Hyon E; Park, Jin Bong; Jo, Eun-Kyeong. GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections. Nature Communications. 2018;9(1):4184.  PubMed
Comments: Used in: ICC
Mori, Hiroyuki; Fukuhara, Takasuke; Ono, Chikako; Tamura, Tomokazu; Sato, Asuka; Fauzyah, Yuzy; Wada, Masami; Okamoto, Toru; Noda, Takeshi; Yoshimori, Tamotsu; Matsuura, Yoshiharu. Induction of selective autophagy in cells replicating hepatitis C virus genome. The Journal Of General Virology. 2018;99(12):1643-1657.  PubMed
Comments: Used in: ICC
Janssen, Anne F J; Katrukha, Eugene A; van Straaten, Wendy; Verlhac, Pauline; Reggiori, Fulvio; Kapitein, Lukas C. Probing aggrephagy using chemically-induced protein aggregates. Nature Communications. 2018;9(1):4245.  PubMed
Comments: Used in: ICC
Horibe, Akio; Eid, Nabil; Ito, Yuko; Otsuki, Yoshinori; Kondo, Yoichi. Ethanol-Induced Autophagy in Sertoli Cells Is Specifically Marked at Androgen-Dependent Stages of the Spermatogenic Cycle: Potential Mechanisms and Implications. International Journal Of Molecular Sciences. 2019;20(1)  PubMed
Comments: Used in: IHC
Lu, Shen-Zhao; Guo, Yong-Shun; Liang, Pei-Zhou; Zhang, Shu-Zhen; Yin, Shu; Yin, Yan-Qing; Wang, Xiao-Min; Ding, Fei; Gu, Xiao-Song; Zhou, Jia-Wei. Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation. Translational Neurodegeneration. 8:3.  PubMed
Comments: Used in: WB
Lu, Shen-Zhao; Guo, Yong-Shun; Liang, Pei-Zhou; Zhang, Shu-Zhen; Yin, Shu; Yin, Yan-Qing; Wang, Xiao-Min; Ding, Fei; Gu, Xiao-Song; Zhou, Jia-Wei. Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation. Translational Neurodegeneration. 8:3.  PubMed
Comments: Used in: IHC
Schulthess, Julie; Pandey, Sumeet; Capitani, Melania; Rue-Albrecht, Kevin C; Arnold, Isabelle; Franchini, Fanny; Chomka, Agnieszka; Ilott, Nicholas E; Johnston, Daniel G W; Pires, Elisabete; McCullagh, James; Sansom, Stephen N; Arancibia-Cárcamo, Carolina V; Uhlig, Holm H; Powrie, Fiona. The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages. Immunity. 2019;50(2):432-445.e7.  PubMed
Comments: Used in: ICC
Ma, Biao; Cheng, Hongcheng; Mu, Chenglong; Geng, Guangfeng; Zhao, Tian; Luo, Qian; Ma, Kaili; Chang, Rui; Liu, Qiangqiang; Gao, Ruize; Nie, Junli; Xie, Jiaying; Han, Jinxue; Chen, Linbo; Ma, Gui; Zhu, Yushan; Chen, Quan. The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Nature Communications. 2019;10(1):1034.  PubMed
Comments: Used in: WB
Ma, Biao; Cheng, Hongcheng; Mu, Chenglong; Geng, Guangfeng; Zhao, Tian; Luo, Qian; Ma, Kaili; Chang, Rui; Liu, Qiangqiang; Gao, Ruize; Nie, Junli; Xie, Jiaying; Han, Jinxue; Chen, Linbo; Ma, Gui; Zhu, Yushan; Chen, Quan. The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Nature Communications. 2019;10(1):1034.  PubMed
Comments: Used in: ICC
Hsu, Yung-Ho; Chuang, Hsiao-Chi; Lee, Yu-Hsuan; Lin, Yuh-Feng; Chen, Yi-Jie; Hsiao, Ta-Chih; Wu, Mei-Yi; Chiu, Hui-Wen. Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo. Free Radical Biology & Medicine. 2019;135:235-244.  PubMed
Comments: Used in: WB
Hsu, Yung-Ho; Chuang, Hsiao-Chi; Lee, Yu-Hsuan; Lin, Yuh-Feng; Chen, Yi-Jie; Hsiao, Ta-Chih; Wu, Mei-Yi; Chiu, Hui-Wen. Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo. Free Radical Biology & Medicine. 2019;135:235-244.  PubMed
Comments: Used in: IHC
Nakajima, Shinsuke; Nishimoto, Yuki; Tateya, Sanshiro; Iwahashi, Yasuyuki; Okamatsu-Ogura, Yuko; Saito, Masayuki; Ogawa, Wataru; Tamori, Yoshikazu. Fat-specific protein 27α inhibits autophagy-dependent lipid droplet breakdown in white adipocytes. Journal Of Diabetes Investigation. 2019;10(6):1419-1429.  PubMed
Comments: Used in: IF
Eid, Nabil; Ito, Yuko; Horibe, Akio; Otsuki, Yoshinori; Kondo, Yoichi. Ethanol-Induced Mitochondrial Damage in Sertoli Cells is Associated with Parkin Overexpression and Activation of Mitophagy. Cells. 2019;8(3)  PubMed
Comments: Used in: WB
Eid, Nabil; Ito, Yuko; Horibe, Akio; Otsuki, Yoshinori; Kondo, Yoichi. Ethanol-Induced Mitochondrial Damage in Sertoli Cells is Associated with Parkin Overexpression and Activation of Mitophagy. Cells. 2019;8(3)  PubMed
Comments: Used in: IHC
Eid, Nabil; Ito, Yuko; Horibe, Akio; Otsuki, Yoshinori; Kondo, Yoichi. Ethanol-Induced Mitochondrial Damage in Sertoli Cells is Associated with Parkin Overexpression and Activation of Mitophagy. Cells. 2019;8(3)  PubMed
Ding, Xianming; Jiang, Xiao; Tian, Rui; Zhao, Pengwei; Li, Lin; Wang, Xinyi; Chen, She; Zhu, Yushan; Mei, Mei; Bao, Shilai; Liu, Wei; Tang, Zaiming; Sun, Qiming. RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells. Autophagy. 2019;15(10):1774-1786.  PubMed
Comments: Used in: WB
Ding, Xianming; Jiang, Xiao; Tian, Rui; Zhao, Pengwei; Li, Lin; Wang, Xinyi; Chen, She; Zhu, Yushan; Mei, Mei; Bao, Shilai; Liu, Wei; Tang, Zaiming; Sun, Qiming. RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells. Autophagy. 2019;15(10):1774-1786.  PubMed
Comments: Used in: ICC
Slowicka, Karolina; Serramito-Gómez, Inmaculada; Boada-Romero, Emilio; Martens, Arne; Sze, Mozes; Petta, Ioanna; Vikkula, Hanna K; De Rycke, Riet; Parthoens, Eef; Lippens, Saskia; Savvides, Savvas N; Wullaert, Andy; Vereecke, Lars; Pimentel-Muiños, Felipe X; van Loo, Geert. Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis. Nature Communications. 2019;10(1):1834.  PubMed
Comments: Used in: WB
Abdullah, Amar; Zhang, Moses; Frugier, Tony; Bedoui, Sammy; Taylor, Juliet M; Crack, Peter J. STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury. Journal Of Neuroinflammation. 2018;15(1):323.  PubMed
Comments: Used in: WB
Wei, Ran; Enaka, Mayu; Muragaki, Yasuteru. Activation of KEAP1/NRF2/P62 signaling alleviates high phosphate-induced calcification of vascular smooth muscle cells by suppressing reactive oxygen species production. Scientific Reports. 2019;9(1):10366.  PubMed
Comments: Used in: WB
Nakashima, Akitoshi; Cheng, Shi-Bin; Kusabiraki, Tae; Motomura, Kenichiro; Aoki, Aiko; Ushijima, Akemi; Ono, Yosuke; Tsuda, Sayaka; Shima, Tomoko; Yoshino, Osamu; Sago, Haruhiko; Matsumoto, Kenji; Sharma, Surendra; Saito, Shigeru. Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts. Scientific Reports. 2019;9(1):11466.  PubMed
Comments: Used in: ICC
Nakashima, Akitoshi; Cheng, Shi-Bin; Kusabiraki, Tae; Motomura, Kenichiro; Aoki, Aiko; Ushijima, Akemi; Ono, Yosuke; Tsuda, Sayaka; Shima, Tomoko; Yoshino, Osamu; Sago, Haruhiko; Matsumoto, Kenji; Sharma, Surendra; Saito, Shigeru. Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts. Scientific Reports. 2019;9(1):11466.  PubMed
Comments: Used in: WB
Gao, Likun; Wang, Zhi; Lu, Danhua; Huang, Jinling; Liu, Jin; Hong, Li. Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells. Cell Death & Disease. 2019;10(8):609.  PubMed
Comments: Used in: WB
Dai, Anbang; Yu, Li; Wang, Hong-Wei. WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes. Nature Communications. 2019;10(1):3699.  PubMed
Comments: Used in: WB
Zhou, Jiali; Kang, Xincong; Luo, Yushuang; Yuan, Yuju; Wu, Yanyang; Wang, Meijun; Liu, Dongbo. Glibenclamide-Induced Autophagy Inhibits Its Insulin Secretion-Improving Function in β Cells. International Journal Of Endocrinology. 2019:1265175.  PubMed
Comments: Used in: WB
Kozako, Tomohiro; Aikawa, Akiyoshi; Ohsugi, Takeo; Uchida, Yu-Ichiro; Kato, Naho; Sato, Keisuke; Ishitsuka, Kenji; Yoshimitsu, Makoto; Honda, Shin-Ichiro. High expression of NAMPT in adult T-cell leukemia/lymphoma and anti-tumor activity of a NAMPT inhibitor. European Journal Of Pharmacology. 2019;865:172738.  PubMed
Comments: Used in: WB
Kondo, Saki; Fukazawa, Ayumi; Karasawa, Takuya; Terada, Shin. Effects of long-term exercise training for different durations on pancreatic amylase activity and intestinal glucose transporter content in rats. Physiological Reports. 2019;7(20):e14255.  PubMed
Comments: Used in: WB
Sun, Xiaolei; Wu, Anguo; Kwan Law, Betty Yuen; Liu, Chaolin; Zeng, Wu; Ling Qiu, Alena Cong; Han, Yu; He, Yanzheng; Wai Wong, Vincent Kam. The active components derived from Penthorum chinensePursh protect against oxidative-stress-induced vascular injury via autophagy induction. Free Radical Biology & Medicine. 2020;146:160-180.  PubMed
Comments: Used in: WB
Nettesheim, April; Shim, Myoung Sup; Hirt, Josh; Liton, Paloma B. Transcriptome analysis reveals autophagy as regulator of TGFβ/Smad-induced fibrogenesis in trabecular meshwork cells. Scientific Reports. 2019;9(1):16092.  PubMed
Comments: Used in: WB
Scotto Rosato, A; Montefusco, S; Soldati, C; Di Paola, S; Capuozzo, A; Monfregola, J; Polishchuk, E; Amabile, A; Grimm, C; Lombardo, A; De Matteis, M A; Ballabio, A; Medina, D L. TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway. Nature Communications. 2019;10(1):5630.  PubMed
Comments: Used in: IF
Jang, Hanbit; Park, Seulki; Kim, Jaehoon; Kim, Jong Hwan; Kim, Seon-Young; Cho, Sayeon; Park, Sung Goo; Park, Byoung Chul; Kim, Sunhong; Kim, Jeong-Hoon. The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNAInduced Silencing of NF-κB-Inducing Kinase. Molecules And Cells. 2020;43(1):23-33.  PubMed
Comments: Used in: WB
Nakamura, Takemasa; Shimizu, Takashi; Uda, Akihiko; Watanabe, Kenta; Watarai, Masahisa. Soluble lytic transglycosylase SLT of Francisella novicida is involved in intracellular growth and immune suppression. Plos One. 14(12):e0226778.  PubMed
Comments: Used in: ICC
Omi, Jumpei; Watanabe-Takahashi, Miho; Igai, Katsura; Shimizu, Eiko; Tseng, Ching-Yi; Miyasaka, Tomohiro; Waku, Tsuyoshi; Hama, Shinichiro; Nakanishi, Rieka; Goto, Yuki; Nishino, Yuri; Miyazawa, Atsuo; Natori, Yasuhiro; Yamashita, Makoto; Nishikawa, Kiyotaka. The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection. Nature Communications. 2020;11(1):162.  PubMed
Comments: Used in: ICC
Ye, Xiaoxia; Zhu, Mingming; Che, Xiaohang; Wang, Huiyang; Liang, Xing-Jie; Wu, Chunfu; Xue, Xue; Yang, Jingyu. Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation. Journal Of Neuroinflammation. 2020;17(1):18.  PubMed
Comments: Used in: WB
Boukhalfa, Asma; Nascimbeni, Anna Chiara; Ramel, Damien; Dupont, Nicolas; Hirsch, Emilio; Gayral, Stephanie; Laffargue, Muriel; Codogno, Patrice; Morel, Etienne. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nature Communications. 2020;11(1):294.  PubMed
Comments: Used in: IHC
He, Xiu; Chen, Shi; Li, Chao; Ban, Jiaqi; Wei, Yungeng; He, Yangyang; Liu, Fangwei; Chen, Ying; Chen, Jie. Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages. Cells. 2020;9(1)  PubMed
Comments: Used in: WB
Ogawa-Akiyama, Ayu; Sugiyama, Hitoshi; Kitagawa, Masashi; Tanaka, Keiko; Kano, Yuzuki; Mise, Koki; Otaka, Nozomu; Tanabe, Katsuyuki; Morinaga, Hiroshi; Kinomura, Masaru; Uchida, Haruhito A; Wada, Jun. Podocyte autophagy is associated with foot process effacement and proteinuria in patients with minimal change nephrotic syndrome. Plos One. 15(1):e0228337.  PubMed
Comments: Used in: IHC
Dong, S; Aguirre-Hernandez, C; Scrivo, A; Eliscovich, C; Arias, E; Bravo-Cordero, J J; Cuervo, A M. Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo. Natur