Application: IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Gene Name: LAMTOR1
Alternative Gene Name: C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000030842: 99%, ENSRNOG00000020016: 97%
Entrez Gene ID: 55004
Uniprot ID: Q6IAA8
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Gene Name: LAMTOR1
Alternative Gene Name: C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000030842: 99%, ENSRNOG00000020016: 97%
Entrez Gene ID: 55004
Uniprot ID: Q6IAA8
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti LAMTOR1 pAb (ATL-HPA002997) | |
| Antigen | PrEST Antigen LAMTOR1 (ATL-APrEST78877) |
| Documents & Links for Anti LAMTOR1 pAb (ATL-HPA002997) | |
| Datasheet | Anti LAMTOR1 pAb (ATL-HPA002997) Datasheet (External Link) |
| Vendor Page | Anti LAMTOR1 pAb (ATL-HPA002997) at Atlas |
| Documents & Links for Anti LAMTOR1 pAb (ATL-HPA002997) | |
| Datasheet | Anti LAMTOR1 pAb (ATL-HPA002997) Datasheet (External Link) |
| Vendor Page | Anti LAMTOR1 pAb (ATL-HPA002997) |
| Citations for Anti LAMTOR1 pAb (ATL-HPA002997) – 7 Found |
| LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning. J Cell Biol. 2017 Dec 4;216(12):4199-4215. doi: 10.1083/jcb.201703061. Epub 2017 Oct 9. PubMed |
| Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts. Proteomics. 2010 Nov;10(22):4117-27. doi: 10.1002/pmic.201000258. Epub 2010 Nov 2. PubMed |
| The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection. J Cell Sci. 2012 Jun 1;125(Pt 11):2698-708. doi: 10.1242/jcs.100073. Epub 2012 Mar 16. PubMed |
| MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. Autophagy. 2012 Jun;8(6):903-14. doi: 10.4161/auto.19653. Epub 2012 May 11. PubMed |
| mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J. 2015 Sep 2;34(17):2272-90. doi: 10.15252/embj.201590992. Epub 2015 Jul 2. PubMed |
| UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity. Elife. 2018 Jul 18;7:e37993. doi: 10.7554/eLife.37993. PubMed |
| Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo. Nat Commun. 2022 Oct 20;13(1):6212. doi: 10.1038/s41467-022-33951-0. PubMed |