Application: WB, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Protein Description: integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Gene Name: ITGA5
Alternative Gene Name: CD49e, FNRA
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000000555: 85%, ENSRNOG00000057451: 82%
Entrez Gene ID: 3678
Uniprot ID: P08648
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Protein Description: integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Gene Name: ITGA5
Alternative Gene Name: CD49e, FNRA
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000000555: 85%, ENSRNOG00000057451: 82%
Entrez Gene ID: 3678
Uniprot ID: P08648
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti ITGA5 pAb (ATL-HPA002642 w/enhanced validation) | |
| Antigen | PrEST Antigen ITGA5 (ATL-APrEST86565) |
| Documents & Links for Anti ITGA5 pAb (ATL-HPA002642 w/enhanced validation) | |
| Datasheet | Anti ITGA5 pAb (ATL-HPA002642 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ITGA5 pAb (ATL-HPA002642 w/enhanced validation) at Atlas |
| Documents & Links for Anti ITGA5 pAb (ATL-HPA002642 w/enhanced validation) | |
| Datasheet | Anti ITGA5 pAb (ATL-HPA002642 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ITGA5 pAb (ATL-HPA002642 w/enhanced validation) |
| Citations for Anti ITGA5 pAb (ATL-HPA002642 w/enhanced validation) – 4 Found |
| Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer. Cell. 2017 Dec 14;171(7):1611-1624.e24. doi: 10.1016/j.cell.2017.10.044. Epub 2017 Nov 30. PubMed |
| Survivin promotion of melanoma metastasis requires upregulation of α5 integrin. Carcinogenesis. 2013 Sep;34(9):2137-44. doi: 10.1093/carcin/bgt155. Epub 2013 May 2. PubMed |
| ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer. Sci Adv. 2019 Sep 4;5(9):eaax2770. doi: 10.1126/sciadv.aax2770. eCollection 2019 Sep. PubMed |
| Integrin α5 subunit is required for the tumor supportive role of fibroblasts in colorectal adenocarcinoma and serves as a potential stroma prognostic marker. Mol Oncol. 2019 Dec;13(12):2697-2714. doi: 10.1002/1878-0261.12583. Epub 2019 Nov 6. PubMed |