Application: WB, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Rat
Protein Description: integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Gene Name: ITGA3
Alternative Gene Name: CD49c, GAP-B3, MSK18, VCA-2, VLA3a
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000001507: 84%, ENSRNOG00000004276: 82%
Entrez Gene ID: 3675
Uniprot ID: P26006
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Rat
Protein Description: integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Gene Name: ITGA3
Alternative Gene Name: CD49c, GAP-B3, MSK18, VCA-2, VLA3a
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000001507: 84%, ENSRNOG00000004276: 82%
Entrez Gene ID: 3675
Uniprot ID: P26006
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti ITGA3 pAb (ATL-HPA008572 w/enhanced validation) | |
| Antigen | PrEST Antigen ITGA3 (ATL-APrEST86765) |
| Documents & Links for Anti ITGA3 pAb (ATL-HPA008572 w/enhanced validation) | |
| Datasheet | Anti ITGA3 pAb (ATL-HPA008572 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ITGA3 pAb (ATL-HPA008572 w/enhanced validation) at Atlas |
| Documents & Links for Anti ITGA3 pAb (ATL-HPA008572 w/enhanced validation) | |
| Datasheet | Anti ITGA3 pAb (ATL-HPA008572 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ITGA3 pAb (ATL-HPA008572 w/enhanced validation) |
| Citations for Anti ITGA3 pAb (ATL-HPA008572 w/enhanced validation) – 7 Found |
| α3β1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of the Hippo Pathway. Cancer Res. 2016 Nov 15;76(22):6577-6587. doi: 10.1158/0008-5472.CAN-16-1483. Epub 2016 Sep 28. PubMed |
| Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer. Br J Cancer. 2017 Apr 11;116(8):1077-1087. doi: 10.1038/bjc.2017.43. Epub 2017 Mar 21. PubMed |
| Regulation of ITGA3 by the anti-tumor miR-199 family inhibits cancer cell migration and invasion in head and neck cancer. Cancer Sci. 2017 Aug;108(8):1681-1692. doi: 10.1111/cas.13298. Epub 2017 Jul 4. PubMed |
| Tumor-suppressive microRNA-223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer. Cancer Sci. 2016 Jan;107(1):84-94. doi: 10.1111/cas.12842. Epub 2015 Dec 5. PubMed |
| Deep sequencing-based microRNA expression signatures in head and neck squamous cell carcinoma: dual strands of pre-miR-150 as antitumor miRNAs. Oncotarget. 2017 May 2;8(18):30288-30304. doi: 10.18632/oncotarget.16327. PubMed |
| Involvement of anti-tumor miR-124-3p and its targets in the pathogenesis of pancreatic ductal adenocarcinoma: direct regulation of ITGA3 and ITGB1 by miR-124-3p. Oncotarget. 2018 Jun 22;9(48):28849-28865. doi: 10.18632/oncotarget.25599. eCollection 2018 Jun 22. PubMed |
| High integrin α3 expression is associated with poor prognosis in patients with non-small cell lung cancer. Transl Lung Cancer Res. 2020 Aug;9(4):1361-1378. doi: 10.21037/tlcr-19-633. PubMed |