Monoclonal antibody of 100 µl targeting IL-18 for WB, NT.
| Product Specifications | |
| Application | WB, Neutralization |
| Reactivity | Mouse |
| Clonality | Monoclonal IgG2a |
| Host | Rat |
| Immunogen | Recombinant mouse IL-18 |
| Gene ID - Human | |
| Gene ID - Mouse | |
| Formulation | 100 µg IgG in 100 µl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Citations for Anti-IL-18 (Clone 39-3F) (Mouse) mAb (Clone: 39-3F) – 9 Found |
| Hoshino, T; Kawase, Y; Okamoto, M; Yokota, K; Yoshino, K; Yamamura, K; Miyazaki, J; Young, H A; Oizumi, K. Cutting edge: IL-18-transgenic mice: in vivo evidence of a broad role for IL-18 in modulating immune function. Journal Of Immunology (Baltimore, Md. : 1950). 2001;166(12):7014-8. PubMed - Comments: Used in: WB |
| Lertmemongkolchai, G; Cai, G; Hunter, C A; Bancroft, G J. Bystander activation of CD8+ T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens. Journal Of Immunology (Baltimore, Md. : 1950). 2001;166(2):1097-105. PubMed - Comments: Used in: NT |
| Seino, Hitomi; Ueda, Haruyasu; Kokai, Masahiro; Tsuji, Noriko M; Kashiwamura, Shinichiro; Morita, Yoshio; Okamura, Haruki. IL-18 mediates the formation of stress-induced, histamine-dependent gastric lesions. American Journal Of Physiology. Gastrointestinal And Liver Physiology. 2007;292(1):G262-7. PubMed - Comments: Used in: WB |
| Hoshino, Tomoaki; Kato, Seiya; Oka, Naoki; Imaoka, Haruki; Kinoshita, Takashi; Takei, Satoko; Kitasato, Yasuhiko; Kawayama, Tomotaka; Imaizumi, Tsutomu; Yamada, Kentaro; Young, Howard A; Aizawa, Hisamichi. Pulmonary inflammation and emphysema: role of the cytokines IL-18 and IL-13. American Journal Of Respiratory And Critical Care Medicine. 2007;176(1):49-62. PubMed - Comments: Used in: WB |
| Venkatachalam, Kaliyamurthi; Prabhu, Sumanth D; Reddy, Venkatapuram Seenu; Boylston, William H; Valente, Anthony J; Chandrasekar, Bysani. Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury. The Journal Of Biological Chemistry. 2009;284(12):7853-65. PubMed - Comments: Used in: WB |
| Fujiwara, Hideaki; Docampo, Melissa D; Riwes, Mary; Peltier, Daniel; Toubai, Tomomi; Henig, Israel; Wu, S Julia; Kim, Stephanie; Taylor, Austin; Brabbs, Stuart; Liu, Chen; Zajac, Cynthia; Oravecz-Wilson, Katherine; Sun, Yaping; Núñez, Gabriel; Levine, John E; van den Brink, Marcel R M; Ferrara, James L M; Reddy, Pavan. Microbial metabolite sensor GPR43 controls severity of experimental GVHD. Nature Communications. 2018;9(1):3674. PubMed - Comments: Used in: WB |
| Yamanishi, Kyosuke; Maeda, Seishi; Kuwahara-Otani, Sachi; Hashimoto, Takuya; Ikubo, Kaoru; Mukai, Keiichiro; Nakasho, Keiji; Gamachi, Naomi; El-Darawish, Yosif; Li, Wen; Okuzaki, Daisuke; Watanabe, Yuko; Yamanishi, Hiromichi; Okamura, Haruki; Matsunaga, Hisato. Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia. Journal Of Translational Medicine. 2018;16(1):314. PubMed - Comments: Used in: WB |
| Chakravarti, Deepavali; Hu, Baoli; Mao, Xizeng; Rashid, Asif; Li, Jiexi; Li, Jun; Liao, Wen-Ting; Whitley, Elizabeth M; Dey, Prasenjit; Hou, Pingping; LaBella, Kyle A; Chang, Andrew; Wang, Guocan; Spring, Denise J; Deng, Pingna; Zhao, Di; Liang, Xin; Lan, Zhengdao; Lin, Yiyun; Sarkar, Sharmistha; Terranova, Christopher; Deribe, Yonathan Lissanu; Blutt, Sarah E; Okhuysen, Pablo; Zhang, Jianhua; Vilar, Eduardo; Nielsen, Ole Haagen; Dupont, Andrew; Younes, Mamoun; Patel, Kalyani R; Shroyer, Noah F; Rai, Kunal; Estes, Mary K; Wang, Y Alan; Bertuch, Alison A; DePinho, Ronald A. Telomere dysfunction activates YAP1 to drive tissue inflammation. Nature Communications. 2020;11(1):4766. PubMed - Comments: Used in: WB |
| Ambati, Jayakrishna; Magagnoli, Joseph; Leung, Hannah; Wang, Shao-Bin; Andrews, Chris A; Fu, Dongxu; Pandey, Akshat; Sahu, Srabani; Narendran, Siddharth; Hirahara, Shuichiro; Fukuda, Shinichi; Sun, Jian; Pandya, Lekha; Ambati, Meenakshi; Pereira, Felipe; Varshney, Akhil; Cummings, Tammy; Hardin, James W; Edun, Babatunde; Bennett, Charles L; Ambati, Kameshwari; Fowler, Benjamin J; Kerur, Nagaraj; Röver, Christian; Leitinger, Norbert; Werner, Brian C; Stein, Joshua D; Sutton, S Scott; Gelfand, Bradley D. Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development. Nature Communications. 2020;11(1):4737. PubMed - Comments: Used in: WB |