Application: WB, ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: HNF1 homeobox B
Gene Name: HNF1B
Alternative Gene Name: HNF1beta, LFB3, MODY5, TCF2, VHNF1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000020679: 97%, ENSRNOG00000002598: 97%
Entrez Gene ID: 6928
Uniprot ID: P35680
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: HNF1 homeobox B
Gene Name: HNF1B
Alternative Gene Name: HNF1beta, LFB3, MODY5, TCF2, VHNF1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000020679: 97%, ENSRNOG00000002598: 97%
Entrez Gene ID: 6928
Uniprot ID: P35680
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti HNF1B pAb (ATL-HPA002083 w/enhanced validation) | |
| Antigen | PrEST Antigen HNF1B (ATL-APrEST84742) |
| Documents & Links for Anti HNF1B pAb (ATL-HPA002083 w/enhanced validation) | |
| Datasheet | Anti HNF1B pAb (ATL-HPA002083 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti HNF1B pAb (ATL-HPA002083 w/enhanced validation) at Atlas |
| Documents & Links for Anti HNF1B pAb (ATL-HPA002083 w/enhanced validation) | |
| Datasheet | Anti HNF1B pAb (ATL-HPA002083 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti HNF1B pAb (ATL-HPA002083 w/enhanced validation) |
| Citations for Anti HNF1B pAb (ATL-HPA002083 w/enhanced validation) – 19 Found |
| Molecular Analysis of Mixed Endometrial Carcinomas Shows Clonality in Most Cases. Am J Surg Pathol. 2016 Feb;40(2):166-180. doi: 10.1097/PAS.0000000000000536. PubMed |
| Dissection of transcriptional and cis-regulatory control of differentiation in human pancreatic cancer. EMBO J. 2016 Mar 15;35(6):595-617. doi: 10.15252/embj.201592404. Epub 2016 Jan 14. PubMed |
| Prognostic relevance of molecular subtypes and master regulators in pancreatic ductal adenocarcinoma. BMC Cancer. 2016 Aug 12;16:632. doi: 10.1186/s12885-016-2540-6. PubMed |
| Caudal migration and proliferation of renal progenitors regulates early nephron segment size in zebrafish. Sci Rep. 2016 Oct 19;6:35647. doi: 10.1038/srep35647. PubMed |
| Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor. Cancer Med. 2018 Sep;7(9):4744-4754. doi: 10.1002/cam4.1724. Epub 2018 Aug 14. PubMed |
| Establishment and characterization of a novel ovarian high-grade serous carcinoma cell line-IPO43. Cancer Cell Int. 2022 Apr 30;22(1):175. doi: 10.1186/s12935-022-02600-3. PubMed |
| Genomic profiling of papillary renal cell tumours identifies small regions of DNA alterations: a possible role of HNF1B in tumour development. Histopathology. 2011 May;58(6):934-43. doi: 10.1111/j.1365-2559.2011.03795.x. Epub 2011 Mar 25. PubMed |
| Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis. PLoS One. 2013 Sep 18;8(9):e74625. doi: 10.1371/journal.pone.0074625. eCollection 2013. PubMed |
| Hepatocyte nuclear factor-1β is not a specific marker of clear cell carcinoma in serous effusions. Cancer Cytopathol. 2014 Feb;122(2):153-8. doi: 10.1002/cncy.21353. Epub 2013 Sep 24. PubMed |
| Long-term primary culture of a clear cell ovarian carcinoma reveals an epithelial-mesenchymal cooperative interaction. Cancer Cell Int. 2015 Sep 24;15:88. doi: 10.1186/s12935-015-0243-8. eCollection 2015. PubMed |
| Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells. PLoS One. 2016 May 19;11(5):e0154912. doi: 10.1371/journal.pone.0154912. eCollection 2016. PubMed |
| Investigation of HNF-1B as a diagnostic biomarker for pancreatic ductal adenocarcinoma. Biomark Res. 2018 Jul 27;6:25. doi: 10.1186/s40364-018-0139-6. eCollection 2018. PubMed |
| Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors. Stem Cell Res Ther. 2018 Oct 25;9(1):277. doi: 10.1186/s13287-018-1038-3. PubMed |
| Napsin-A and AMACR are Superior to HNF-1β in Distinguishing Between Mesonephric Carcinomas and Clear Cell Carcinomas of the Gynecologic Tract. Appl Immunohistochem Mol Morphol. 2020 Sep;28(8):593-601. doi: 10.1097/PAI.0000000000000801. PubMed |
| FOXA2 controls the cis-regulatory networks of pancreatic cancer cells in a differentiation grade-specific manner. EMBO J. 2019 Oct 15;38(20):e102161. doi: 10.15252/embj.2019102161. Epub 2019 Sep 17. PubMed |
| Analysis of expression, epigenetic, and genetic changes of HNF1B in 130 kidney tumours. Sci Rep. 2020 Oct 13;10(1):17151. doi: 10.1038/s41598-020-74059-z. PubMed |
| Endometrial Tumor Classification by Histomorphology and Biomarkers in the Nurses' Health Study. J Cancer Epidemiol. 2021 Mar 12;2021:8884364. doi: 10.1155/2021/8884364. eCollection 2021. PubMed |
| Protocol for Large-Scale Production of Kidney Organoids from Human Pluripotent Stem Cells. STAR Protoc. 2020 Oct 29;1(3):100150. doi: 10.1016/j.xpro.2020.100150. eCollection 2020 Dec 18. PubMed |
| Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility. Nat Commun. 2021 May 24;12(1):3044. doi: 10.1038/s41467-021-23237-2. PubMed |