Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Product Specifications | |
Application | WB, IHC, ELISA |
Reactivity | Human |
Clonality | Monoclonal (Clone No.: 4G10) |
Documents & Links for Anti Histone H2B type 1-K mAb (Clone 4G10) | |
Datasheet | Anti Histone H2B type 1-K mAb (Clone 4G10) Datasheet |
Vendor Page | Anti Histone H2B type 1-K mAb (Clone 4G10) at CUSABIO |
Documents & Links for Anti Histone H2B type 1-K mAb (Clone 4G10) | |
Datasheet | Anti Histone H2B type 1-K mAb (Clone 4G10) Datasheet |
Vendor Page | Anti Histone H2B type 1-K mAb (Clone 4G10) |