IHC image of CSB-RA794900A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Anti GZMB mAb (Clone 6A1)

Catalog No:
CSB-RA794900A0HU-50
$210.00
Application: IHC, IF, ELISA 
Clonality: Monoclonal 
Purification: Purified - Affinity 
Reactivity: Human 
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Documents & Links for Anti GZMB mAb (Clone 6A1)
DatasheetAnti GZMB mAb (Clone 6A1) Datasheet
Vendor PageAnti GZMB mAb (Clone 6A1) at CUSABIO

Documents & Links for Anti GZMB mAb (Clone 6A1)
DatasheetAnti GZMB mAb (Clone 6A1) Datasheet
Vendor PageAnti GZMB mAb (Clone 6A1)