This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Product Specifications | |
Application | IHC, IF, ELISA |
Reactivity | Human |
Clonality | Monoclonal (Clone No.: 6A1) |
Documents & Links for Anti GZMB mAb (Clone 6A1) | |
Datasheet | Anti GZMB mAb (Clone 6A1) Datasheet |
Vendor Page | Anti GZMB mAb (Clone 6A1) at CUSABIO |
Documents & Links for Anti GZMB mAb (Clone 6A1) | |
Datasheet | Anti GZMB mAb (Clone 6A1) Datasheet |
Vendor Page | Anti GZMB mAb (Clone 6A1) |