Application: WB
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: gasdermin D
Gene Name: GSDMD
Alternative Gene Name: DF5L, FLJ12150, GSDMDC1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000022575: 61%, ENSRNOG00000007728: 63%
Entrez Gene ID: 79792
Uniprot ID: P57764
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: gasdermin D
Gene Name: GSDMD
Alternative Gene Name: DF5L, FLJ12150, GSDMDC1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000022575: 61%, ENSRNOG00000007728: 63%
Entrez Gene ID: 79792
Uniprot ID: P57764
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti GSDMD pAb (ATL-HPA044487 w/enhanced validation) | |
| Antigen | PrEST Antigen GSDMD (ATL-APrEST76404) |
| Documents & Links for Anti GSDMD pAb (ATL-HPA044487 w/enhanced validation) | |
| Datasheet | Anti GSDMD pAb (ATL-HPA044487 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti GSDMD pAb (ATL-HPA044487 w/enhanced validation) at Atlas |
| Documents & Links for Anti GSDMD pAb (ATL-HPA044487 w/enhanced validation) | |
| Datasheet | Anti GSDMD pAb (ATL-HPA044487 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti GSDMD pAb (ATL-HPA044487 w/enhanced validation) |
| Citations for Anti GSDMD pAb (ATL-HPA044487 w/enhanced validation) – 5 Found |
| Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages. Cell Death Discov. 2021 Oct 30;7(1):327. doi: 10.1038/s41420-021-00716-5. PubMed |
| Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis. Sci Immunol. 2018 Aug 24;3(26):eaat2738. doi: 10.1126/sciimmunol.aat2738. PubMed |
| Human polymorphisms in GSDMD alter the inflammatory response. J Biol Chem. 2020 Mar 6;295(10):3228-3238. doi: 10.1074/jbc.RA119.010604. Epub 2020 Jan 27. PubMed |
| Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases. Cell Rep. 2021 Apr 13;35(2):108998. doi: 10.1016/j.celrep.2021.108998. PubMed |
| Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis. J Biol Chem. 2023 Feb;299(2):102908. doi: 10.1016/j.jbc.2023.102908. Epub 2023 Jan 13. PubMed |