Application: ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: granulin
Gene Name: GRN
Alternative Gene Name: CLN11, PCDGF, PGRN
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000034708: 84%, ENSRNOG00000021031: 83%
Entrez Gene ID: 2896
Uniprot ID: P28799
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: granulin
Gene Name: GRN
Alternative Gene Name: CLN11, PCDGF, PGRN
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000034708: 84%, ENSRNOG00000021031: 83%
Entrez Gene ID: 2896
Uniprot ID: P28799
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti GRN pAb (ATL-HPA008763 w/enhanced validation) | |
| Antigen | PrEST Antigen GRN (ATL-APrEST86882) |
| Documents & Links for Anti GRN pAb (ATL-HPA008763 w/enhanced validation) | |
| Datasheet | Anti GRN pAb (ATL-HPA008763 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti GRN pAb (ATL-HPA008763 w/enhanced validation) at Atlas |
| Documents & Links for Anti GRN pAb (ATL-HPA008763 w/enhanced validation) | |
| Datasheet | Anti GRN pAb (ATL-HPA008763 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti GRN pAb (ATL-HPA008763 w/enhanced validation) |
| Citations for Anti GRN pAb (ATL-HPA008763 w/enhanced validation) – 6 Found |
| Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations. eNeuro. 2017 Aug 18;4(4):ENEURO.0100-17.2017. doi: 10.1523/ENEURO.0100-17.2017. eCollection 2017 Jul-Aug. PubMed |
| Granulin Expression in Hamsters during Opisthorchis viverrini Infection-Induced Cholangiocarcinogenesis. Asian Pac J Cancer Prev. 2018 Sep 26;19(9):2437-2445. doi: 10.22034/APJCP.2018.19.9.2437. PubMed |
| Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. J Clin Invest. 2011 Feb;121(2):784-99. doi: 10.1172/JCI43757. Epub 2011 Jan 25. PubMed |
| Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2849-E2858. doi: 10.1073/pnas.1722344115. Epub 2018 Mar 6. PubMed |
| A High-throughput Bead-based Affinity Assay Enables Analysis of Genital Protein Signatures in Women At Risk of HIV Infection. Mol Cell Proteomics. 2019 Mar;18(3):461-476. doi: 10.1074/mcp.RA118.000757. Epub 2018 Nov 30. PubMed |
| Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020 Mar 16;15(1):21. doi: 10.1186/s13024-020-00369-5. PubMed |