Application: WB, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Protein Description: glycine dehydrogenase (decarboxylating)
Gene Name: GLDC
Alternative Gene Name: GCSP, NKH
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000024827: 96%, ENSRNOG00000011599: 96%
Entrez Gene ID: 2731
Uniprot ID: P23378
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Protein Description: glycine dehydrogenase (decarboxylating)
Gene Name: GLDC
Alternative Gene Name: GCSP, NKH
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000024827: 96%, ENSRNOG00000011599: 96%
Entrez Gene ID: 2731
Uniprot ID: P23378
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti GLDC pAb (ATL-HPA002318 w/enhanced validation) | |
| Antigen | PrEST Antigen GLDC (ATL-APrEST86183) |
| Documents & Links for Anti GLDC pAb (ATL-HPA002318 w/enhanced validation) | |
| Datasheet | Anti GLDC pAb (ATL-HPA002318 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti GLDC pAb (ATL-HPA002318 w/enhanced validation) at Atlas |
| Documents & Links for Anti GLDC pAb (ATL-HPA002318 w/enhanced validation) | |
| Datasheet | Anti GLDC pAb (ATL-HPA002318 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti GLDC pAb (ATL-HPA002318 w/enhanced validation) |
| Citations for Anti GLDC pAb (ATL-HPA002318 w/enhanced validation) – 6 Found |
| LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature. 2016 Nov 17;539(7629):390-395. doi: 10.1038/nature20132. Epub 2016 Oct 31. PubMed |
| Expression of Neural Crest Markers GLDC and ERRFI1 is Correlated with Melanoma Prognosis. Cancers (Basel). 2019 Jan 11;11(1):76. doi: 10.3390/cancers11010076. PubMed |
| Glycine by MR spectroscopy is an imaging biomarker of glioma aggressiveness. Neuro Oncol. 2020 Jul 7;22(7):1018-1029. doi: 10.1093/neuonc/noaa034. PubMed |
| Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress. Physiol Rep. 2021 Aug;9(15):e14991. doi: 10.14814/phy2.14991. PubMed |
| SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. Nature. 2015 Apr 16;520(7547):363-7. doi: 10.1038/nature14363. Epub 2015 Apr 8. PubMed |
| Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice. J Clin Invest. 2020 Mar 2;130(3):1446-1452. doi: 10.1172/JCI132360. PubMed |