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| Product Specifications | |
| Application | IP, WB, IHC |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal IgG2a |
| Host | Mouse |
| Immunogen | Full-length recombinant human FHL2 |
| Gene ID - Human | |
| Gene ID - Mouse | |
| Formulation | 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative iscontained. |
| Documents & Links for Anti-FHL2 (Human) mAb (Clone: 11-134) | |
| Datasheet | Anti-FHL2 (Human) mAb (Clone: 11-134) Datasheet |
| Documents & Links for Anti-FHL2 (Human) mAb (Clone: 11-134) | |
| Datasheet | Anti-FHL2 (Human) mAb (Clone: 11-134) Datasheet |
| Citations for Anti-FHL2 (Human) mAb (Clone: 11-134) – 32 Found |
| Weinert, Stefanie; Bergmann, Nora; Luo, Xiuju; Erdmann, Bettina; Gotthardt, Michael. M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere. The Journal Of Cell Biology. 2006;173(4):559-70. PubMed - Comments: Used in: WB |
| Kang, David E; Yoon, Il Sang; Repetto, Emanuela; Busse, Tracy; Yermian, Nader; Ie, Listya; Koo, Edward H. Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors. Selectivity of PS2 in platelet-derived growth factor signaling. The Journal Of Biological Chemistry. 2005;280(36):31537-47. PubMed - Comments: Used in: WB |
| Sun, Jianxin; Yan, Guijun; Ren, Aixia; You, Bei; Liao, James K. FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1. Circulation Research. 2006;99(5):468-76. PubMed - Comments: Used in: WB |
| Sun, Jianxin; Yan, Guijun; Ren, Aixia; You, Bei; Liao, James K. FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1. Circulation Research. 2006;99(5):468-76. PubMed - Comments: Used in: IP |
| Wang, Jide; Yang, Yi; Xia, Harry H X; Gu, Qing; Lin, Marie C M; Jiang, Bo; Peng, Ying; Li, Guoqing; An, Xiaomeng; Zhang, Yali; Zhuang, Zehao; Zhang, Zhenshu; Kung, Hsiang Fu; Wong, Benjamin C Y. Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. Gastroenterology. 2007;132(3):1066-76. PubMed - Comments: Used in: WB |
| Wang, Jide; Yang, Yi; Xia, Harry H X; Gu, Qing; Lin, Marie C M; Jiang, Bo; Peng, Ying; Li, Guoqing; An, Xiaomeng; Zhang, Yali; Zhuang, Zehao; Zhang, Zhenshu; Kung, Hsiang Fu; Wong, Benjamin C Y. Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. Gastroenterology. 2007;132(3):1066-76. PubMed - Comments: Used in: IHC |
| Labalette, Charlotte; Nouët, Yann; Sobczak-Thepot, Joëlle; Armengol, Carolina; Levillayer, Florence; Gendron, Marie-Claude; Renard, Claire-Angélique; Regnault, Béatrice; Chen, Ju; Buendia, Marie-Annick; Wei, Yu. The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation. The Journal Of Biological Chemistry. 2008;283(22):15201-8. PubMed - Comments: Used in: WB |
| Labalette, Charlotte; Nouët, Yann; Sobczak-Thepot, Joëlle; Armengol, Carolina; Levillayer, Florence; Gendron, Marie-Claude; Renard, Claire-Angélique; Regnault, Béatrice; Chen, Ju; Buendia, Marie-Annick; Wei, Yu. The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation. The Journal Of Biological Chemistry. 2008;283(22):15201-8. PubMed - Comments: Used in: ChIP |
| Labalette, Charlotte; Nouët, Yann; Levillayer, Florence; Armengol, Carolina; Renard, Claire-Angélique; Soubigou, Guillaume; Xia, Tian; Buendia, Marie-Annick; Wei, Yu. The LIM-only protein FHL2 mediates ras-induced transformation through cyclin D1 and p53 pathways. Plos One. 3(11):e3761. PubMed - Comments: Used in: WB |
| Neuman, Nicole A; Ma, Susan; Schnitzler, Gavin R; Zhu, Yan; Lagna, Giorgio; Hata, Akiko. The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone. The Journal Of Biological Chemistry. 2009;284(19):13202-12. PubMed - Comments: Used in: ChIP |
| Ewen, Elizabeth P; Snyder, Christine M; Wilson, Megan; Desjardins, Danielle; Naya, Francisco J. The Mef2A transcription factor coordinately regulates a costamere gene program in cardiac muscle. The Journal Of Biological Chemistry. 2011;286(34):29644-53. PubMed - Comments: Used in: WB |
| Ewen, Elizabeth P; Snyder, Christine M; Wilson, Megan; Desjardins, Danielle; Naya, Francisco J. The Mef2A transcription factor coordinately regulates a costamere gene program in cardiac muscle. The Journal Of Biological Chemistry. 2011;286(34):29644-53. PubMed - Comments: Used in: IHC |
| Hojayev, Berdymammet; Rothermel, Beverly A; Gillette, Thomas G; Hill, Joseph A. FHL2 binds calcineurin and represses pathological cardiac growth. Molecular And Cellular Biology. 2012;32(19):4025-34. PubMed - Comments: Used in: WB |
| Hojayev, Berdymammet; Rothermel, Beverly A; Gillette, Thomas G; Hill, Joseph A. FHL2 binds calcineurin and represses pathological cardiac growth. Molecular And Cellular Biology. 2012;32(19):4025-34. PubMed - Comments: Used in: IHC |
| Li, Szu-Yuan; Huang, Po-Hsun; Tarng, Der-Cherng; Lin, Tzu-Ping; Yang, Wu-Chang; Chang, Yen-Hwa; Yang, An-Hang; Lin, Chih-Ching; Yang, Muh-Hwa; Chen, Jaw-Wen; Schmid-Schönbein, Geert W; Chien, Shu; Chu, Pao-Hsien; Lin, Shing-Jong. Four-and-a-Half LIM Domains Protein 2 Is a Coactivator of Wnt Signaling in Diabetic Kidney Disease. Journal Of The American Society Of Nephrology : Jasn. 2015;26(12):3072-84. PubMed - Comments: Used in: WB |
| Li, Szu-Yuan; Huang, Po-Hsun; Tarng, Der-Cherng; Lin, Tzu-Ping; Yang, Wu-Chang; Chang, Yen-Hwa; Yang, An-Hang; Lin, Chih-Ching; Yang, Muh-Hwa; Chen, Jaw-Wen; Schmid-Schönbein, Geert W; Chien, Shu; Chu, Pao-Hsien; Lin, Shing-Jong. Four-and-a-Half LIM Domains Protein 2 Is a Coactivator of Wnt Signaling in Diabetic Kidney Disease. Journal Of The American Society Of Nephrology : Jasn. 2015;26(12):3072-84. PubMed - Comments: Used in: ICC |
| Li, Szu-Yuan; Huang, Po-Hsun; Tarng, Der-Cherng; Lin, Tzu-Ping; Yang, Wu-Chang; Chang, Yen-Hwa; Yang, An-Hang; Lin, Chih-Ching; Yang, Muh-Hwa; Chen, Jaw-Wen; Schmid-Schönbein, Geert W; Chien, Shu; Chu, Pao-Hsien; Lin, Shing-Jong. Four-and-a-Half LIM Domains Protein 2 Is a Coactivator of Wnt Signaling in Diabetic Kidney Disease. Journal Of The American Society Of Nephrology : Jasn. 2015;26(12):3072-84. PubMed - Comments: Used in: IHC |
| Rachmin, Inbal; Amsalem, Eden; Golomb, Eliahu; Beeri, Ronen; Gilon, Dan; Fang, Pengfei; Nechushtan, Hovav; Kay, Gillian; Guo, Min; Yiqing, Peter Li; Foo, Roger S-Y; Fisher, David E; Razin, Ehud; Tshori, Sagi. FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy. International Journal Of Cardiology. 2015;195:85-94. PubMed - Comments: Used in: WB |
| Rachmin, Inbal; Amsalem, Eden; Golomb, Eliahu; Beeri, Ronen; Gilon, Dan; Fang, Pengfei; Nechushtan, Hovav; Kay, Gillian; Guo, Min; Yiqing, Peter Li; Foo, Roger S-Y; Fisher, David E; Razin, Ehud; Tshori, Sagi. FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy. International Journal Of Cardiology. 2015;195:85-94. PubMed - Comments: Used in: IP |
| Rachmin, Inbal; Amsalem, Eden; Golomb, Eliahu; Beeri, Ronen; Gilon, Dan; Fang, Pengfei; Nechushtan, Hovav; Kay, Gillian; Guo, Min; Yiqing, Peter Li; Foo, Roger S-Y; Fisher, David E; Razin, Ehud; Tshori, Sagi. FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy. International Journal Of Cardiology. 2015;195:85-94. PubMed - Comments: Used in: ChIP |
| Yan, Qingqing; Zhang, Wenjing; Wu, Yao; Wu, Meiyan; Zhang, Mengnan; Shi, Xinpeng; Zhao, Jinjun; Nan, Qingzhen; Chen, Ye; Wang, Long; Cheng, Tianming; Li, Jiachu; Bai, Yang; Liu, Side; Wang, Jide. KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2. Oncotarget. 2015;6(28):25402-17. PubMed - Comments: Used in: WB |
| Yan, Qingqing; Zhang, Wenjing; Wu, Yao; Wu, Meiyan; Zhang, Mengnan; Shi, Xinpeng; Zhao, Jinjun; Nan, Qingzhen; Chen, Ye; Wang, Long; Cheng, Tianming; Li, Jiachu; Bai, Yang; Liu, Side; Wang, Jide. KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2. Oncotarget. 2015;6(28):25402-17. PubMed - Comments: Used in: ICC |
| Yan, Qingqing; Zhang, Wenjing; Wu, Yao; Wu, Meiyan; Zhang, Mengnan; Shi, Xinpeng; Zhao, Jinjun; Nan, Qingzhen; Chen, Ye; Wang, Long; Cheng, Tianming; Li, Jiachu; Bai, Yang; Liu, Side; Wang, Jide. KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2. Oncotarget. 2015;6(28):25402-17. PubMed - Comments: Used in: IHC |
| Jin, H; Lee, K; Kim, Y-H; Oh, H K; Maeng, Y-I; Kim, T-H; Suh, D-S; Bae, J. Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells. Oncogene. 2016;35(39):5106-18. PubMed - Comments: Used in: WB |
| Jin, H; Lee, K; Kim, Y-H; Oh, H K; Maeng, Y-I; Kim, T-H; Suh, D-S; Bae, J. Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells. Oncogene. 2016;35(39):5106-18. PubMed - Comments: Used in: ICC |
| Jin, H; Lee, K; Kim, Y-H; Oh, H K; Maeng, Y-I; Kim, T-H; Suh, D-S; Bae, J. Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells. Oncogene. 2016;35(39):5106-18. PubMed - Comments: Used in: IHC |
| Wu, M; Wang, J; Tang, W; Zhan, X; Li, Y; Peng, Y; Huang, X; Bai, Y; Zhao, J; Li, A; Chen, C; Chen, Y; Peng, H; Ren, Y; Li, G; Liu, S; Wang, J. FOXK1 interaction with FHL2 promotes proliferation, invasion and metastasis in colorectal cancer. Oncogenesis. 2016;5(11):e271. PubMed - Comments: Used in: WB |
| Wu, M; Wang, J; Tang, W; Zhan, X; Li, Y; Peng, Y; Huang, X; Bai, Y; Zhao, J; Li, A; Chen, C; Chen, Y; Peng, H; Ren, Y; Li, G; Liu, S; Wang, J. FOXK1 interaction with FHL2 promotes proliferation, invasion and metastasis in colorectal cancer. Oncogenesis. 2016;5(11):e271. PubMed - Comments: Used in: ICC |
| Wu, M; Wang, J; Tang, W; Zhan, X; Li, Y; Peng, Y; Huang, X; Bai, Y; Zhao, J; Li, A; Chen, C; Chen, Y; Peng, H; Ren, Y; Li, G; Liu, S; Wang, J. FOXK1 interaction with FHL2 promotes proliferation, invasion and metastasis in colorectal cancer. Oncogenesis. 2016;5(11):e271. PubMed - Comments: Used in: IHC |
| Verset, Laurine; Tommelein, Joke; Decaestecker, Christine; De Vlieghere, Elly; Bracke, Marc; Salmon, Isabelle; De Wever, Olivier; Demetter, Pieter. ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer. Tumour Biology : The Journal Of The International Society For Oncodevelopmental Biology And Medicine. 2017;39(3):1010428317695024. PubMed - Comments: Used in: WB |
| Zhou, S-G; Ma, H-J; Guo, Z-Y; Zhang, W; Yang, X. FHL2 participates in renal interstitial fibrosis by altering the phenotype of renal tubular epithelial cells via regulating the β-catenin pathway. European Review For Medical And Pharmacological Sciences. 2018;22(9):2734-2741. PubMed - Comments: Used in: WB |
| Zhou, S-G; Ma, H-J; Guo, Z-Y; Zhang, W; Yang, X. FHL2 participates in renal interstitial fibrosis by altering the phenotype of renal tubular epithelial cells via regulating the β-catenin pathway. European Review For Medical And Pharmacological Sciences. 2018;22(9):2734-2741. PubMed - Comments: Used in: IHC |
