Application: IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: FAT atypical cadherin 1
Gene Name: FAT1
Alternative Gene Name: CDHF7, CDHR8, FAT
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000070047: 85%, ENSRNOG00000030954: 85%
Entrez Gene ID: 2195
Uniprot ID: Q14517
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: FAT atypical cadherin 1
Gene Name: FAT1
Alternative Gene Name: CDHF7, CDHR8, FAT
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000070047: 85%, ENSRNOG00000030954: 85%
Entrez Gene ID: 2195
Uniprot ID: Q14517
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti FAT1 pAb (ATL-HPA001869 w/enhanced validation) | |
| Antigen | PrEST Antigen FAT1 (ATL-APrEST85144) |
| Documents & Links for Anti FAT1 pAb (ATL-HPA001869 w/enhanced validation) | |
| Datasheet | Anti FAT1 pAb (ATL-HPA001869 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti FAT1 pAb (ATL-HPA001869 w/enhanced validation) at Atlas |
| Documents & Links for Anti FAT1 pAb (ATL-HPA001869 w/enhanced validation) | |
| Datasheet | Anti FAT1 pAb (ATL-HPA001869 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti FAT1 pAb (ATL-HPA001869 w/enhanced validation) |
| Citations for Anti FAT1 pAb (ATL-HPA001869 w/enhanced validation) – 3 Found |
| Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy. PLoS Genet. 2013 Jun;9(6):e1003550. doi: 10.1371/journal.pgen.1003550. Epub 2013 Jun 13. PubMed |
| A soluble form of the giant cadherin Fat1 is released from pancreatic cancer cells by ADAM10 mediated ectodomain shedding. PLoS One. 2014 Mar 13;9(3):e90461. doi: 10.1371/journal.pone.0090461. eCollection 2014. PubMed |
| Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway. Cancer Cell. 2018 Dec 10;34(6):893-905.e8. doi: 10.1016/j.ccell.2018.11.006. PubMed |