Anti-Fas (CD95) mAb (Clone: CH-11)

Catalog No:
MBL-SY-001

Availability: 12PM PT on Dec. 3, 2024

Monoclonal Antibody of 100 µl targeting Fas for FCM, WB.

Product Specifications
Application FC, WB
Reactivity Human
Clonality Monoclonal IgM
Host Mouse
Immunogen FS-7 Human diploid fibroblasts
Gene ID - Human

355

Gene ID - Mouse

14102

Formulation 0.5 mg/mL in PBS/50% glycerol, pH 7.2

Citations for Anti-Fas (CD95) mAb (Clone: CH-11) – 22 Found
Zanin-Zhorov, Alexandra; Hershkoviz, Rami; Hecht, Iris; Cahalon, Liora; Lider, Ofer. Fibronectin-associated Fas ligand rapidly induces opposing and time-dependent effects on the activation and apoptosis of T cells. Journal Of Immunology (Baltimore, Md. : 1950). 2003;171(11):5882-9.  PubMed
Comments: Used in: Function
López-Huertas, María Rosa; Mateos, Elena; Sánchez Del Cojo, María; Gómez-Esquer, Francisco; Díaz-Gil, Gema; Rodríguez-Mora, Sara; López, Juan Antonio; Calvo, Enrique; López-Campos, Guillermo; Alcamí, José; Coiras, Mayte. The presence of HIV-1 Tat protein second exon delays fas protein-mediated apoptosis in CD4+ T lymphocytes: a potential mechanism for persistent viral production. The Journal Of Biological Chemistry. 2013;288(11):7626-7644.  PubMed
Comments: Used in: Function
Murthy, Aditya; Li, Yun; Peng, Ivan; Reichelt, Mike; Katakam, Anand Kumar; Noubade, Rajkumar; Roose-Girma, Merone; DeVoss, Jason; Diehl, Lauri; Graham, Robert R; van Lookeren Campagne, Menno. A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3. Nature. 2014;506(7489):456-62.  PubMed
Comments: Used in: Function
Ma, Li; Gong, Haiyan; Zhu, Haiyan; Ji, Qing; Su, Pei; Liu, Peng; Cao, Shannan; Yao, Jianfeng; Jiang, Linlin; Han, Mingzhe; Ma, Xiaotong; Xiong, Dongsheng; Luo, Hongbo R; Wang, Fei; Zhou, Jiaxi; Xu, Yuanfu. A novel small-molecule tumor necrosis factor α inhibitor attenuates inflammation in a hepatitis mouse model. The Journal Of Biological Chemistry. 2014;289(18):12457-66.  PubMed
Comments: Used in: Function
Liu, Wei; Lin, Yan-Ting; Yan, Xiao-Li; Ding, Ya-Lan; Wu, Yun-Li; Chen, Wan-Nan; Lin, Xu. Hepatitis B virus core protein inhibits Fas-mediated apoptosis of hepatoma cells via regulation of mFas/FasL and sFas expression. Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology. 2015;29(3):1113-23.  PubMed
Comments: Used in: Function
Yanagi, Teruki; Shi, Ranxin; Aza-Blanc, Pedro; Reed, John C; Matsuzawa, Shu-ichi. PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines. Plos One. 10(3):e0119404.  PubMed
Comments: Used in: Function
Cui, X; Zhang, L; Magli, A R; Catera, R; Yan, X-J; Griffin, D O; Rothstein, T L; Barrientos, J; Kolitz, J E; Allen, S L; Rai, K R; Chiorazzi, N; Chu, C C. Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability. Leukemia. 2016;30(1):74-85.  PubMed
Comments: Used in: Function
Tan, Lingbing; Zhang, Chaocan; Dematos, Julien; Kuang, Linlin; Jung, Jae U; Liang, Xiaozhen. CD95 Signaling Inhibits B Cell Receptor-Mediated Gammaherpesvirus Replication in Apoptosis-Resistant B Lymphoma Cells. Journal Of Virology. 2016;90(21):9782-9796.  PubMed
Comments: Used in: Function
Hashiramoto, Akira; Konishi, Yoshitake; Murayama, Koichi; Kawasaki, Hiroki; Yoshida, Kohsuke; Tsumiyama, Ken; Tanaka, Kimie; Mizuhara, Masaru; Shiotsuki, Toshio; Kitamura, Hitomi; Komai, Koichiro; Kimura, Tomoatsu; Yagita, Hideo; Shiozawa, Kazuko; Shiozawa, Shunichi. A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell. The Journal Of Biological Chemistry. 2018;293(6):1933-1943.  PubMed
Comments: Used in: Function
Takaki, Syohei; Eto, Ko. Cytoplasmic localization of programmed cell death 4 contributes to its anti-apoptotic function. Molecular And Cellular Biochemistry. 2018;448(1-2):155-164.  PubMed
Comments: Used in: NT
Kozako, Tomohiro; Mellini, Paolo; Ohsugi, Takeo; Aikawa, Akiyoshi; Uchida, Yu-Ichiro; Honda, Shin-Ichiro; Suzuki, Takayoshi. Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines. Bmc Cancer. 2018;18(1):791.  PubMed
Comments: Used in: Function
Jing, Zhen-Tang; Liu, Wei; Wu, Shu-Xiang; He, Yun; Lin, Yan-Ting; Chen, Wan-Nan; Lin, Xin-Jian; Lin, Xu. Hepatitis B Virus Surface Antigen Enhances the Sensitivity of Hepatocytes to Fas-Mediated Apoptosis via Suppression of AKT Phosphorylation. Journal Of Immunology (Baltimore, Md. : 1950). 2018;201(8):2303-2314.  PubMed
Comments: Used in: Function
Sekiguchi, Yuto; Yamada, Mayuka; Noguchi, Takuya; Noomote, Chise; Tsuchida, Mei; Kudoh, Yuki; Hirata, Yusuke; Matsuzawa, Atsushi. The anti-cancer drug gefitinib accelerates Fas-mediated apoptosis by enhancing caspase-8 activation in cancer cells. The Journal Of Toxicological Sciences. 44(6):435-440.  PubMed
Comments: Used in: Function
Liu, Wei; Jing, Zhen-Tang; Xue, Chao-Rong; Wu, Shu-Xiang; Chen, Wan-Nan; Lin, Xin-Jian; Lin, Xu. PI3K/AKT inhibitors aggravate death receptor-mediated hepatocyte apoptosis and liver injury. Toxicology And Applied Pharmacology. 2019;381:114729.  PubMed
Comments: Used in: Function
Dagenais-Lussier, Xavier; Loucif, Hamza; Cadorel, Hugo; Blumberger, Juliette; Isnard, Stéphane; Bego, Mariana Gé; Cohen, Éric A; Routy, Jean-Pierre; van Grevenynghe, Julien. USP18 is a significant driver of memory CD4 T-cell reduced viability caused by type I IFN signaling during primary HIV-1 infection. Plos Pathogens. 2019;15(10):e1008060.  PubMed
Comments: Used in: Function
Asakawa, Masahiro; Itoh, Michiko; Suganami, Takayoshi; Sakai, Takeru; Kanai, Sayaka; Shirakawa, Ibuki; Yuan, Xunmei; Hatayama, Tomomi; Shimada, Shu; Akiyama, Yoshimitsu; Fujiu, Katsuhito; Inagaki, Yutaka; Manabe, Ichiro; Yamaoka, Shoji; Yamada, Tetsuya; Tanaka, Shinji; Ogawa, Yoshihiro. Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis. Scientific Reports. 2019;9(1):19601.  PubMed
Comments: Used in: Function
Masuda, Azuchi; Isobe, Yasushi; Sugimoto, Koichi; Yoshimori, Mayumi; Arai, Ayako; Komatsu, Norio. Efficient recruitment of c-FLIP(L) to the death-inducing signaling complex leads to Fas resistance in natural killer-cell lymphoma. Cancer Science. 2020;111(3):807-816.  PubMed
Comments: Used in: WB
Masuda, Azuchi; Isobe, Yasushi; Sugimoto, Koichi; Yoshimori, Mayumi; Arai, Ayako; Komatsu, Norio. Efficient recruitment of c-FLIP(L) to the death-inducing signaling complex leads to Fas resistance in natural killer-cell lymphoma. Cancer Science. 2020;111(3):807-816.  PubMed
Comments: Used in: Function
Aoki, Kana; Satoi, Shinsuke; Harada, Shota; Uchida, Seiichi; Iwasa, Yoh; Ikenouchi, Junichi. Coordinated changes in cell membrane and cytoplasm during maturation of apoptotic bleb. Molecular Biology Of The Cell. 2020;31(8):833-844.  PubMed
Comments: Used in: Function
Thiagarajan, D; Fiskesund, R; Frostegård, A; Steen, J; Rahman, M; Vikström, M; Lundström, S; Frostegård, J. Immunoglobulin G1 Antibodies Against Phosphorylcholine Are Associated With Protection in Systemic Lupus Erythematosus and Atherosclerosis: Potential Underlying Mechanisms. Acr Open Rheumatology. 2020;2(6):344-356.  PubMed
Comments: Used in: Function
Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan. Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers In Immunology. 11:973.  PubMed
Comments: Used in: Function
Liu, Dan; Wang, Zhiding; Wang, Huijuan; Ren, Feifei; Li, Yanqin; Zou, Sifan; Xu, Jianqiao; Xie, Lixin. The protective role of miR-223 in sepsis-induced mortality. Scientific Reports. 2020;10(1):17691.  PubMed
Comments: Used in: Function