Anti Exportin-5 (XPO5) mAb (Clone 1D11)

Cosmo Bio

Catalog No: CAC-CEC-024

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Product Description

Background
Exportin-5 (XPO5) is a protein that, in humans, is encoded by the XPO5 gene.[5][6][7] In eukaryotic cells, the primary purpose of XPO5 is to export pre-microRNA (also known as pre-miRNA) out of the nucleus and into the cytoplasm, for further processing by the Dicer enzyme.[8][9][10][11] Once in the cytoplasm, the microRNA (also known as miRNA) can act as a gene silencer by regulating translation of mRNA. Although XPO5 is primarily involved in the transport of pre-miRNA, it has also been reported to transport tRNA.[12] [from: Wikipedia contributors. (2019, February 11). XPO5. In Wikipedia, The Free Encyclopedia. Retrieved 22:11, June 4, 2019, from https://en.wikipedia.org/w/index.php?title=XPO5&oldid=882799194]

Application
Western blotting, 1/1000 to 1/5000
Immunocytochemistry, 1/100 to 1/500

References
Katahira and Yoneda (2011) Traffic. 12:1468-1474.

Product Specifications

• Application: ICC, WB, IF
• Reactivity: Human
• Clonality: Monoclonal (Clone No.: 1D11)
• Host: Rat