Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134).
| Product Specifications | |
| Application | IF, ELISA |
| Reactivity | Human |
| Clonality | Monoclonal (Clone No.: 6F6) |
| Documents & Links for Anti ERBB3 mAb (Clone 6F6) | |
| Datasheet | Anti ERBB3 mAb (Clone 6F6) Datasheet |
| Vendor Page | Anti ERBB3 mAb (Clone 6F6) at CUSABIO |
| Documents & Links for Anti ERBB3 mAb (Clone 6F6) | |
| Datasheet | Anti ERBB3 mAb (Clone 6F6) Datasheet |
| Vendor Page | Anti ERBB3 mAb (Clone 6F6) |