Application: WB, IHC, IF, FC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human, Rat
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human, Rat
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).
| Documents & Links for Anti E2F1 mAb (Clone 1D12) | |
| Datasheet | Anti E2F1 mAb (Clone 1D12) Datasheet |
| Vendor Page | Anti E2F1 mAb (Clone 1D12) at CUSABIO |
| Documents & Links for Anti E2F1 mAb (Clone 1D12) | |
| Datasheet | Anti E2F1 mAb (Clone 1D12) Datasheet |
| Vendor Page | Anti E2F1 mAb (Clone 1D12) |
