Anti-Desmoglein 3 (Mouse) mAb (No Azide) (Clone: AK18)

Catalog No:
MBL-D218-3

Availability: 12PM PT on Dec. 3, 2024

Monoclonal antibody of 100 μg targeting Desmoglein-3 for ICC, IHC, IPP



Product Specifications
Application ICC, IP, IHC
Clonality Monoclonal IgG1
Host Mouse
Immunogen Hybridoma of spleen cells and mouse myeloma cells P3 mouse model of PV
Gene ID - Human

1830

Gene ID - Mouse

13512

Formulation 100 μg IgG in 100 μl volume of PBS, pH 7.2. No preservative is contained.

Citations for Anti-Desmoglein 3 (Mouse) mAb (No Azide) (Clone: AK18) – 4 Found
Tsunoda, Kazuyuki; Ota, Takayuki; Aoki, Miyo; Yamada, Taketo; Nagai, Tetsuo; Nakagawa, Taneaki; Koyasu, Shigeo; Nishikawa, Takeji; Amagai, Masayuki. Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3. Journal Of Immunology (Baltimore, Md. : 1950). 2003;170(4):2170-8.  PubMed
Comments: Used in: IP
Culton, Donna A; McCray, Suzanne K; Park, Moonhee; Roberts, James C; Li, Ning; Zedek, Daniel C; Anhalt, Grant J; Cowley, Dale O; Liu, Zhi; Diaz, Luis A. Mucosal pemphigus vulgaris anti-Dsg3 IgG is pathogenic to the oral mucosa of humanized Dsg3 mice. The Journal Of Investigative Dermatology. 2015;135(6):1590-1597.  PubMed
Comments: Used in: WB
Culton, Donna A; McCray, Suzanne K; Park, Moonhee; Roberts, James C; Li, Ning; Zedek, Daniel C; Anhalt, Grant J; Cowley, Dale O; Liu, Zhi; Diaz, Luis A. Mucosal pemphigus vulgaris anti-Dsg3 IgG is pathogenic to the oral mucosa of humanized Dsg3 mice. The Journal Of Investigative Dermatology. 2015;135(6):1590-1597.  PubMed
Comments: Used in: IHC
Fujii, Etsuko; Funahashi, Shinichi; Taniguchi, Kenji; Kawai, Shigeto; Nakano, Kiyotaka; Kato, Atsuhiko; Suzuki, Masami. Tissue-specific effects of an anti-desmoglein-3 ADCC antibody due to expression of the target antigen and physiological characteristics of the mouse vagina. Journal Of Toxicologic Pathology. 2020;33(2):67-76.  PubMed
Comments: Used in: IHC